Utilization of AlphaFold2 to Predict MFS Protein Conformations after Selective Mutation

por Xiao, Qingjie, Xu, Mengxue, Wang, Weiwei, Wu, Tingting, Zhang, Weizhe, Qin, Wenming, Sun, Bo
Publicado 2022

Mechanistic investigation of a D to N mutation in DAHP synthase that dictates carbon flux into the shikimate pathway in yeast

por Liu, Huayi, Xiao, Qingjie, Wu, Xinxin, Ma, He, Li, Jian, Guo, Xufan, Liu, Zhenyu, Zhang, Yan, Luo, Yunzi
Publicado 2023

Characterization of a promiscuous DNA sulfur binding domain and application in site-directed RNA base editing

por Hu, Wenyue, Yang, Bingxu, Xiao, Qingjie, Wang, Yuli, Shuai, Yuting, Zhao, Gong, Zhang, Lixin, Deng, Zixin, He, Xinyi, Liu, Guang
Publicado 2023

Cryo-EM structure of the human concentrative nucleoside transporter CNT3

por Zhou, Yanxia, Liao, Lianghuan, Wang, Chen, Li, Jialu, Chi, Pengliang, Xiao, Qingjie, Liu, Qingting, Guo, Li, Sun, Linfeng, Deng, Dong
Publicado 2020

Molecular basis for substrate recognition by the bacterial nucleoside transporter NupG

por Wang, Chen, Xiao, Qingjie, Duan, Huaichuan, Li, Jinhong, Zhang, Jiying, Wang, Qisheng, Guo, Li, Hu, Jianping, Sun, Bo, Deng, Dong
Publicado 2021

Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline

por Cheng, Qipeng, Cheung, Yanchu, Liu, Chenyu, Xiao, Qingjie, Sun, Bo, Zhou, Jiahai, Chan, Edward Wai Chi, Zhang, Rong, Chen, Sheng
Publicado 2021

Structural insights into sphingosine-1-phosphate receptor activation

por Yu, Leiye, He, Licong, Gan, Bing, Ti, Rujuan, Xiao, Qingjie, Yang, Xin, Hu, Hongli, Zhu, Lizhe, Wang, Sheng, Ren, Ruobing
Publicado 2022

The crystal structure of MreC provides insights into polymer formation

por Xu, Qin, Sun, Ning, Xiao, Qingjie, Huang, Chia‐ying, Xu, Mengxue, Zhang, Weizhe, Li, Lina, Wang, Qisheng, Olieric, Vincent, Wang, Weiwu, He, Jianhua, Sun, Bo
Publicado 2022

Structural basis for gating mechanism of Pannexin 1 channel

por Mou, Luqiu, Ke, Meng, Song, Mengxiao, Shan, Yuanyue, Xiao, Qingjie, Liu, Qingting, Li, Jialu, Sun, Ke, Pu, Lei, Guo, Li, Geng, Jia, Wu, Jianping, Deng, Dong
Publicado 2020

Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity

por Lin, Sheng, Chen, Hua, Chen, Zimin, Yang, Fanli, Ye, Fei, Zheng, Yue, Yang, Jing, Lin, Xi, Sun, Honglu, Wang, Lingling, Wen, Ao, Dong, Haohao, Xiao, Qingjie, Deng, Dong, Cao, Yu, Lu, Guangwen
Publicado 2021

Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism

por Han, Yufei, Zhuang, Qian, Sun, Bo, Lv, Wenping, Wang, Sheng, Xiao, Qingjie, Pang, Bin, Zhou, Youli, Wang, Fuxing, Chi, Pengliang, Wang, Qisheng, Li, Zhen, Zhu, Lizhe, Li, Fuping, Deng, Dong, Chiang, Ying-Chih, Li, Zhenfei, Ren, Ruobing
Publicado 2021

Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism

por Peng, Xi, Wang, Nan, Zhu, Angqi, Xu, Hanwen, Li, Jialu, Zhou, Yanxia, Wang, Chen, Xiao, Qingjie, Guo, Li, Liu, Fei, Jia, Zhi-jun, Duan, Huaichuan, Hu, Jianping, Yuan, Weidan, Geng, Jia, Yan, Chuangye, Jiang, Xin, Deng, Dong
Publicado 2021

Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1

por Wang, Chen, Yu, Leiye, Zhang, Jiying, Zhou, Yanxia, Sun, Bo, Xiao, Qingjie, Zhang, Minhua, Liu, Huayi, Li, Jinhong, Li, Jialu, Luo, Yunzi, Xu, Jie, Lian, Zhong, Lin, Jingwen, Wang, Xiang, Zhang, Peng, Guo, Li, Ren, Ruobing, Deng, Dong
Publicado 2023