KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells

por Zhu, Zhi-Chuan, Liu, Ji-Wei, Li, Kui, Zheng, Jing, Xiong, Zhi-Qi
Publicado 2018

XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis

por Zhu, Zhi-Chuan, Liu, Ji-Wei, Yang, Can, Zhao, Miao, Xiong, Zhi-Qi
Publicado 2019

Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells

por Zhu, Zhi-Chuan, Liu, Ji-Wei, Yang, Can, Li, Ming-Jie, Wu, Rong-Jie, Xiong, Zhi-Qi
Publicado 2019

Rethinking monogenic neurological diseases

por Chen, Wan-Jin, Cheng, Xuewen, Fu, Ying, Zhao, Miao, McGinley, Jennifer, Westenberger, Ana, Xiong, Zhi-Qi
Publicado 2020

Requirement of TORC1 for Late-Phase Long-Term Potentiation in the Hippocampus

por Zhou, Yang, Wu, Hao, Li, Shuai, Chen, Qian, Cheng, Xue-Wen, Zheng, Jing, Takemori, Hiroshi, Xiong, Zhi-Qi
Publicado 2006

Limbic Epileptogenesis in a Mouse Model of Fragile X Syndrome

por Qiu, Li-Feng, Lu, Ting-Jia, Hu, Xiao-Ling, Yi, Yong-Hong, Liao, Wei-Ping, Xiong, Zhi-Qi
Publicado 2009

mTOR is essential for corticosteroid effects on hippocampal AMPA receptor function and fear memory

por Xiong, Hui, Cassé, Frédéric, Zhou, Yang, Zhou, Ming, Xiong, Zhi-Qi, Joëls, Marian, Martin, Stéphane, Krugers, Harm J.
Publicado 2015

A-Type GABA Receptor as a Central Target of TRPM8 Agonist Menthol

por Zhang, Xiao-Bing, Jiang, Peng, Gong, Neng, Hu, Xiao-Ling, Fei, Da, Xiong, Zhi-Qi, Xu, Lin, Xu, Tian-Le
Publicado 2008

The Pathology of Primary Familial Brain Calcification: Implications for Treatment

por Xu, Xuan, Sun, Hao, Luo, Junyu, Cheng, Xuewen, Lv, Wenqi, Luo, Wei, Chen, Wan-Jin, Xiong, Zhi-Qi, Liu, Jing-Yu
Publicado 2022

ADAM10-Initiated Release of Notch Intracellular Domain Regulates Microtubule Stability and Radial Migration of Cortical Neurons

por Yang, Zhi, Li, Peng-Fei, Chen, Ren-Chao, Wang, Jie, Wang, Shaoran, Shen, Ya, Wu, Xiaohui, Fang, Bing, Cheng, Xuewen, Xiong, Zhi-Qi
Publicado 2017

Repeated methamphetamine exposure decreases plasma brain-derived neurotrophic factor levels in rhesus monkeys

por Zhang, Wenlei, Zhou, Jiahui, Su, Hang, Zhang, Xiaocheng, Song, Weichen, Wang, Zijing, Tang, Chengjie, Uludağ, Kadir, Zhao, Min, Xiong, Zhi-Qi, Zhai, Rongwei, Jiang, Haifeng
Publicado 2023

Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila

por Li, Wenhua, Yao, Aiyu, Zhi, Hui, Kaur, Kuldeep, Zhu, Yong-chuan, Jia, Mingyue, Zhao, Hui, Wang, Qifu, Jin, Shan, Zhao, Guoli, Xiong, Zhi-Qi, Zhang, Yong Q.
Publicado 2016

Accelerated passage of gene-modified monkeys by hormone-induced precocious puberty

por Liu, Zhen, Li, Kui, Cai, Yijun, Liu, Qiming, Zhang, Tikui, Lu, Yong, Nie, Yanhong, Wang, Yan, Yan, Zhiguang, Qu, Yinwei, Li, Yuzhuo, Wang, Zhanyang, Xiong, Zhi-Qi, Sun, Qiang
Publicado 2021

Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons

por Xu, Qiong, Liu, Yuan-yuan, Wang, Xiaoming, Tan, Guo-he, Li, Hui-ping, Hulbert, Samuel W., Li, Chun-yang, Hu, Chun-chun, Xiong, Zhi-qi, Xu, Xiu, Jiang, Yong-hui
Publicado 2018

TMEM151A variants cause paroxysmal kinesigenic dyskinesia

por Li, Hong-Fu, Chen, Yu-Lan, Zhuang, Ling, Chen, Dian-Fu, Ke, Hua-Zhen, Luo, Wen-Jiao, Liu, Gong-Lu, Wu, Sheng-Nan, Zhou, Wen-Hao, Xiong, Zhi-Qi, Wu, Zhi-Ying
Publicado 2021

Author Correction: TMEM151A variants cause paroxysmal kinesigenic dyskinesia

por Li, Hong-Fu, Chen, Yu-Lan, Zhuang, Ling, Chen, Dian-Fu, Ke, Hua-Zhen, Luo, Wen-Jiao, Liu, Gong-Lu, Wu, Sheng-Nan, Zhou, Wen-Hao, Xiong, Zhi-Qi, Wu, Zhi-Ying
Publicado 2021

PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum

por Tan, Guo-He, Liu, Yuan-Yuan, Wang, Lu, Li, Kui, Zhang, Ze-Qiang, Li, Hong-Fu, Yang, Zhong-Fei, Li, Yang, Li, Dan, Wu, Ming-Yue, Yu, Chun-Lei, Long, Juan-Juan, Chen, Ren-Chao, Li, Li-Xi, Yin, Lu-Ping, Liu, Ji-Wei, Cheng, Xue-Wen, Shen, Qi, Shu, You-Sheng, Sakimura, Kenji, Liao, Lu-Jian, Wu, Zhi-Ying, Xiong, Zhi-Qi
Publicado 2018

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

por Zuo, Erwei, Cai, Yi-Jun, Li, Kui, Wei, Yu, Wang, Bang-An, Sun, Yidi, Liu, Zhen, Liu, Jiwei, Hu, Xinde, Wei, Wei, Huo, Xiaona, Shi, Linyu, Tang, Cheng, Liang, Dan, Wang, Yan, Nie, Yan-Hong, Zhang, Chen-Chen, Yao, Xuan, Wang, Xing, Zhou, Changyang, Ying, Wenqin, Wang, Qifang, Chen, Ren-Chao, Shen, Qi, Xu, Guo-Liang, Li, Jinsong, Sun, Qiang, Xiong, Zhi-Qi, Yang, Hui
Publicado 2017

Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

por Zhao, Miao, Su, Hui-Zhen, Zeng, Yi-Heng, Sun, Yuan, Guo, Xin-Xin, Li, Yun-Lu, Wang, Chong, Zhao, Zhi-Yuan, Huang, Xue-Jing, Lin, Kai-Jun, Ye, Zi-Ling, Lin, Bi-Wei, Hong, Shunyan, Zheng, Jitan, Liu, Yao-Bin, Yao, Xiang-Ping, Yang, Dehao, Lu, Ying-Qian, Chen, Hai-Zhu, Zuo, Erwei, Yang, Guang, Wang, Hong-Tao, Huang, Chen-Wei, Lin, Xiao-Hong, Cen, Zhidong, Lai, Lu-Lu, Zhang, Yan-Ke, Li, Xi, Lai, Tianmin, Lin, Jingjing, Zuo, Dan-Dan, Lin, Min-Ting, Liou, Chia-Wei, Kong, Qing-Xia, Yan, Chuan-Zhu, Xiong, Zhi-Qi, Wang, Ning, Luo, Wei, Zhao, Cui-Ping, Cheng, Xuewen, Chen, Wan-Jin
Publicado 2022