DUBs “found in translation”: USP15 controls stability of newly synthesized REST

por Xirodimas, Dimitris P
Publicado 2013

The Essential Functions of NEDD8 Are Mediated via Distinct Surface Regions, and Not by Polyneddylation in Schizosaccharomyces pombe

por Girdwood, David, Xirodimas, Dimitris P., Gordon, Colin
Publicado 2011

The use of the NEDD8 inhibitor MLN4924 (Pevonedistat) in a cyclotherapy approach to protect wild-type p53 cells from MLN4924 induced toxicity

por Malhab, Lara J. Bou, Descamps, Simon, Delaval, Benedicte, Xirodimas, Dimitris P.
Publicado 2016

Characterization of MRFAP1 Turnover and Interactions Downstream of the NEDD8 Pathway

por Larance, Mark, Kirkwood, Kathryn J., Xirodimas, Dimitris P., Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I.
Publicado 2012

Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly

por Kassouf, Toufic, Shrivastava, Rohit, Meszka, Igor, Bailly, Aymeric, Polanowska, Jolanta, Trauchessec, Helene, Mandrioli, Jessica, Carra, Serena, Xirodimas, Dimitris P.
Publicado 2023

NEDDylation promotes nuclear protein aggregation and protects the Ubiquitin Proteasome System upon proteotoxic stress

por Maghames, Chantal M., Lobato-Gil, Sofia, Perrin, Aurelien, Trauchessec, Helene, Rodriguez, Manuel S., Urbach, Serge, Marin, Philippe, Xirodimas, Dimitris P.
Publicado 2018

Stable Isotope Labeling with Amino acids in Nematodes

por Larance, Mark, Bailly, Aymeric P., Pourkarimi, Ehsan, Hay, Ronald T., Buchanan, Grant, Coulthurst, Sarah, Xirodimas, Dimitris P., Gartner, Anton, Lamond, Angus I.
Publicado 2011

Antibody RING-Mediated Destruction of Endogenous Proteins

por Ibrahim, Adel F.M., Shen, Linnan, Tatham, Michael H., Dickerson, David, Prescott, Alan R., Abidi, Naima, Xirodimas, Dimitris P., Hay, Ronald T.
Publicado 2020

The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

por Bailly, Aymeric P., Perrin, Aurelien, Serrano-Macia, Marina, Maghames, Chantal, Leidecker, Orsolya, Trauchessec, Helene, Martinez-Chantar, M.L., Gartner, Anton, Xirodimas, Dimitris P.
Publicado 2019

Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis

por Serrano-Maciá, Marina, Simón, Jorge, González-Rellan, Maria J., Azkargorta, Mikel, Goikoetxea-Usandizaga, Naroa, Lopitz-Otsoa, Fernando, De Urturi, Diego Saenz, Rodríguez-Agudo, Rubén, Lachiondo-Ortega, Sofia, Mercado-Gomez, Maria, Gutiérrez de Juan, Virginia, Bizkarguenaga, Maider, Fernández-Ramos, David, Buque, Xabier, Baselli, Guido A., Valenti, Luca V.C., Iruzubieta, Paula, Crespo, Javier, Villa, Erica, Banales, Jesus M., Avila, Matias A., Marin, Jose J.G., Aspichueta, Patricia, Sutherland, James, Barrio, Rosa, Mayor, Ugo, Elortza, Félix, Xirodimas, Dimitris P., Nogueiras, Rubén, Delgado, Teresa C., Martínez-Chantar, María Luz
Publicado 2021