Image-based cell sorting using focused travelling surface acoustic waves

por Nawaz, Ahmad Ahsan, Soteriou, Despina, Xu, Catherine K., Goswami, Ruchi, Herbig, Maik, Guck, Jochen, Girardo, Salvatore
Publicado 2023

Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans

por Perni, Michele, Mannini, Benedetta, Xu, Catherine K., Kumita, Janet R., Dobson, Christopher M., Chiti, Fabrizio, Vendruscolo, Michele
Publicado 2021

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

por Cascella, Roberta, Chen, Serene W., Bigi, Alessandra, Camino, José D., Xu, Catherine K., Dobson, Christopher M., Chiti, Fabrizio, Cremades, Nunilo, Cecchi, Cristina
Publicado 2021

Uncovering the universality of self-replication in protein aggregation and its link to disease

por Meisl, Georg, Xu, Catherine K., Taylor, Jonathan D., Michaels, Thomas C. T., Levin, Aviad, Otzen, Daniel, Klenerman, David, Matthews, Steve, Linse, Sara, Andreasen, Maria, Knowles, Tuomas P. J.
Publicado 2022

The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity

por Xu, Catherine K., Castellana-Cruz, Marta, Chen, Serene W., Du, Zhen, Meisl, Georg, Levin, Aviad, Mannini, Benedetta, Itzhaki, Laura S., Knowles, Tuomas P. J., Dobson, Christopher M., Cremades, Nunilo, Kumita, Janet R.
Publicado 2022

In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease

por Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L., Sanchez, Justin S., Xu, Catherine K., Duff, Karen E., Johnson, Keith A., Rowe, James B., Hyman, Bradley T., Knowles, Tuomas P. J., Klenerman, David
Publicado 2021

N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates

por Bell, Rosie, Thrush, Rebecca J., Castellana-Cruz, Marta, Oeller, Marc, Staats, Roxine, Nene, Aishwarya, Flagmeier, Patrick, Xu, Catherine K., Satapathy, Sandeep, Galvagnion, Celine, Wilson, Mark R., Dobson, Christopher M., Kumita, Janet R., Vendruscolo, Michele
Publicado 2022

Single-Molecule Sizing through Nanocavity Confinement

por Jacquat, Raphaël P. B., Krainer, Georg, Peter, Quentin A. E., Babar, Ali Nawaz, Vanderpoorten, Oliver, Xu, Catherine K., Welsh, Timothy J., Kaminski, Clemens F., Keyser, Ulrich F., Baumberg, Jeremy J., Knowles, Tuomas P. J.
Publicado 2023

A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

por Cataldi, Rodrigo, Chia, Sean, Pisani, Katarina, Ruggeri, Francesco S., Xu, Catherine K., Šneideris, Tomas, Perni, Michele, Sarwat, Sunehera, Joshi, Priyanka, Kumita, Janet R., Linse, Sara, Habchi, Johnny, Knowles, Tuomas P. J., Mannini, Benedetta, Dobson, Christopher M., Vendruscolo, Michele
Publicado 2021

Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

por Cataldi, Rodrigo, Chia, Sean, Pisani, Katarina, Ruggeri, Francesco S., Xu, Catherine K., Šneideris, Tomas, Perni, Michele, Sarwat, Sunehera, Joshi, Priyanka, Kumita, Janet R., Linse, Sara, Habchi, Johnny, Knowles, Tuomas P. J., Mannini, Benedetta, Dobson, Christopher M., Vendruscolo, Michele
Publicado 2021

Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses

por Pansieri, Jonathan, Iashchishyn, Igor A., Fakhouri, Hussein, Ostojić, Lucija, Malisauskas, Mantas, Musteikyte, Greta, Smirnovas, Vytautas, Schneider, Matthias M., Scheidt, Tom, Xu, Catherine K., Meisl, Georg, Knowles, Tuomas P. J., Gazit, Ehud, Antoine, Rodolphe, Morozova-Roche, Ludmilla A.
Publicado 2020

Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma

por Schneider, Matthias M, Emmenegger, Marc, Xu, Catherine K, Condado Morales, Itzel, Meisl, Georg, Turelli, Priscilla, Zografou, Chryssa, Zimmermann, Manuela R, Frey, Beat M, Fiedler, Sebastian, Denninger, Viola, Jacquat, Raphaël PB, Madrigal, Lidia, Ilsley, Alison, Kosmoliaptsis, Vasilis, Fiegler, Heike, Trono, Didier, Knowles, Tuomas PJ, Aguzzi, Adriano
Publicado 2021

ThX – a next-generation probe for the early detection of amyloid aggregates

por Needham, Lisa-Maria, Weber, Judith, Varela, Juan A., Fyfe, James W. B., Do, Dung T., Xu, Catherine K., Tutton, Luke, Cliffe, Rachel, Keenlyside, Benjamin, Klenerman, David, Dobson, Christopher M., Hunter, Christopher A., Müller, Karin H., O'Holleran, Kevin, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Publicado 2020

Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism

por Limbocker, Ryan, Mannini, Benedetta, Ruggeri, Francesco S., Cascella, Roberta, Xu, Catherine K., Perni, Michele, Chia, Sean, Chen, Serene W., Habchi, Johnny, Bigi, Alessandra, Kreiser, Ryan P., Wright, Aidan K., Albright, J. Alex, Kartanas, Tadas, Kumita, Janet R., Cremades, Nunilo, Zasloff, Michael, Cecchi, Cristina, Knowles, Tuomas P. J., Chiti, Fabrizio, Vendruscolo, Michele, Dobson, Christopher M.
Publicado 2020

Trodusquemine enhances Aβ(42) aggregation but suppresses its toxicity by displacing oligomers from cell membranes

por Limbocker, Ryan, Chia, Sean, Ruggeri, Francesco S., Perni, Michele, Cascella, Roberta, Heller, Gabriella T., Meisl, Georg, Mannini, Benedetta, Habchi, Johnny, Michaels, Thomas C. T., Challa, Pavan K., Ahn, Minkoo, Casford, Samuel T., Fernando, Nilumi, Xu, Catherine K., Kloss, Nina D., Cohen, Samuel I. A., Kumita, Janet R., Cecchi, Cristina, Zasloff, Michael, Linse, Sara, Knowles, Tuomas P. J., Chiti, Fabrizio, Vendruscolo, Michele, Dobson, Christopher M.
Publicado 2019

Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers

por Limbocker, Ryan, Staats, Roxine, Chia, Sean, Ruggeri, Francesco S., Mannini, Benedetta, Xu, Catherine K., Perni, Michele, Cascella, Roberta, Bigi, Alessandra, Sasser, Liam R., Block, Natalie R., Wright, Aidan K., Kreiser, Ryan P., Custy, Edward T., Meisl, Georg, Errico, Silvia, Habchi, Johnny, Flagmeier, Patrick, Kartanas, Tadas, Hollows, Jared E., Nguyen, Lam T., LeForte, Kathleen, Barbut, Denise, Kumita, Janet R., Cecchi, Cristina, Zasloff, Michael, Knowles, Tuomas P. J., Dobson, Christopher M., Chiti, Fabrizio, Vendruscolo, Michele
Publicado 2021

Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease

por Perni, Michele, van der Goot, Annemieke, Limbocker, Ryan, van Ham, Tjakko J., Aprile, Francesco A., Xu, Catherine K., Flagmeier, Patrick, Thijssen, Karen, Sormanni, Pietro, Fusco, Giuliana, Chen, Serene W., Challa, Pavan K., Kirkegaard, Julius B., Laine, Romain F., Ma, Kai Yu, Müller, Martin B. D., Sinnige, Tessa, Kumita, Janet R., Cohen, Samuel I. A., Seinstra, Renée, Kaminski Schierle, Gabriele S., Kaminski, Clemens F., Barbut, Denise, De Simone, Alfonso, Knowles, Tuomas P. J., Zasloff, Michael, Nollen, Ellen A. A., Vendruscolo, Michele, Dobson, Christopher M.
Publicado 2021

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region

por Emmenegger, Marc, De Cecco, Elena, Lamparter, David, Jacquat, Raphaël P.B., Riou, Julien, Menges, Dominik, Ballouz, Tala, Ebner, Daniel, Schneider, Matthias M., Morales, Itzel Condado, Doğançay, Berre, Guo, Jingjing, Wiedmer, Anne, Domange, Julie, Imeri, Marigona, Moos, Rita, Zografou, Chryssa, Batkitar, Leyla, Madrigal, Lidia, Schneider, Dezirae, Trevisan, Chiara, Gonzalez-Guerra, Andres, Carrella, Alessandra, Dubach, Irina L., Xu, Catherine K., Meisl, Georg, Kosmoliaptsis, Vasilis, Malinauskas, Tomas, Burgess-Brown, Nicola, Owens, Ray, Hatch, Stephanie, Mongkolsapaya, Juthathip, Screaton, Gavin R., Schubert, Katharina, Huck, John D., Liu, Feimei, Pojer, Florence, Lau, Kelvin, Hacker, David, Probst-Müller, Elsbeth, Cervia, Carlo, Nilsson, Jakob, Boyman, Onur, Saleh, Lanja, Spanaus, Katharina, von Eckardstein, Arnold, Schaer, Dominik J., Ban, Nenad, Tsai, Ching-Ju, Marino, Jacopo, Schertler, Gebhard F.X., Ebert, Nadine, Thiel, Volker, Gottschalk, Jochen, Frey, Beat M., Reimann, Regina R., Hornemann, Simone, Ring, Aaron M., Knowles, Tuomas P.J., Puhan, Milo A., Althaus, Christian L., Xenarios, Ioannis, Stuart, David I., Aguzzi, Adriano
Publicado 2023