Senescent Tumor CD8(+) T Cells: Mechanisms of Induction and Challenges to Immunotherapy

por Liu, Wei, Stachura, Paweł, Xu, Haifeng C., Bhatia, Sanil, Borkhardt, Arndt, Lang, Philipp A., Pandyra, Aleksandra A.
Publicado 2020

Differential Modulation of miR-122 Transcription by TGFβ1/BMP6: Implications for Nonresolving Inflammation and Hepatocarcinogenesis

por Paluschinski, Martha, Kordes, Claus, Vucur, Mihael, Buettner, Veronika, Roderburg, Christoph, Xu, Haifeng C., Shinte, Prashant V., Lang, Philipp A., Luedde, Tom, Castoldi, Mirco
Publicado 2023

Usp18 Driven Enforced Viral Replication in Dendritic Cells Contributes to Break of Immunological Tolerance in Autoimmune Diabetes

por Honke, Nadine, Shaabani, Namir, Zhang, Dong-Er, Iliakis, George, Xu, Haifeng C., Häussinger, Dieter, Recher, Mike, Löhning, Max, Lang, Philipp A., Lang, Karl S.
Publicado 2013

Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis

por Li, Qian, Yan, Yan, Liu, Jia, Huang, Xuan, Zhang, Xiaoyong, Kirschning, Carsten, Xu, Haifeng C., Lang, Philipp A., Dittmer, Ulf, Zhang, Ejuan, Lu, Mengji
Publicado 2019

Communicator-Driven Data Preprocessing Improves Deep Transfer Learning of Histopathological Prediction of Pancreatic Ductal Adenocarcinoma

por Kronberg, Raphael M., Haeberle, Lena, Pfaus, Melanie, Xu, Haifeng C., Krings, Karina S., Schlensog, Martin, Rau, Tilman, Pandyra, Aleksandra A., Lang, Karl S., Esposito, Irene, Lang, Philipp A.
Publicado 2022

Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications

por Liu, Wei, Stachura, Paweł, Xu, Haifeng C., Umesh Ganesh, Nikkitha, Cox, Fiona, Wang, Ruifeng, Lang, Karl S., Gopalakrishnan, Jay, Häussinger, Dieter, Homey, Bernhard, Lang, Philipp A., Pandyra, Aleksandra A.
Publicado 2020

Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling

por Zoellner, Nele, Coesfeld, Noémi, De Vos, Frederik Henry, Denter, Jennifer, Xu, Haifeng C., Zimmer, Elena, Knebel, Birgit, Al-Hasani, Hadi, Mossner, Sofie, Lang, Philipp A., Floss, Doreen M., Scheller, Jürgen
Publicado 2022

NK cell–intrinsic FcεRIγ limits CD8(+) T-cell expansion and thereby turns an acute into a chronic viral infection

por Duhan, Vikas, Hamdan, Thamer A., Xu, Haifeng C., Shinde, Prashant, Bhat, Hilal, Li, Fanghui, Al-Matary, Yahya, Häussinger, Dieter, Bezgovsek, Judith, Friedrich, Sarah-Kim, Hardt, Cornelia, Lang, Philipp A., Lang, Karl S.
Publicado 2019

T-cell STAT3 is required for the maintenance of humoral immunity to LCMV

por McIlwain, David R, Grusdat, Melanie, Pozdeev, Vitaly I, Xu, Haifeng C, Shinde, Prashant, Reardon, Colin, Hao, Zhenyue, Beyer, Marc, Bergthaler, Andreas, Häussinger, Dieter, Nolan, Garry P, Lang, Karl S, Lang, Philipp A
Publicado 2015

Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection

por Lang, Elisabeth, Pozdeev, Vitaly I., Shinde, Prashant V., Xu, Haifeng C., Sundaram, Balamurugan, Zhuang, Yuan, Poschmann, Gereon, Huang, Jun, Stühler, Kai, Pandyra, Aleksandra A., Keitel, Verena, Häussinger, Dieter, Lang, Karl S., Lang, Philipp A.
Publicado 2018

Slow viral propagation during initial phase of infection leads to viral persistence in mice

por Xu, Haifeng C., Wang, Ruifeng, Shinde, Prashant V., Walotka, Lara, Huang, Anfei, Poschmann, Gereon, Huang, Jun, Liu, Wei, Stühler, Kai, Schaal, Heiner, Bergthaler, Andreas, Pandyra, Aleksandra A., Hardt, Cornelia, Lang, Karl S., Lang, Philipp A.
Publicado 2021

Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors

por Stachura, Paweł, Liu, Wei, Xu, Haifeng C., Wlodarczyk, Agnès, Stencel, Olivia, Pandey, Piyush, Vogt, Melina, Bhatia, Sanil, Picard, Daniel, Remke, Marc, Lang, Karl S., Häussinger, Dieter, Homey, Bernhard, Lang, Philipp A., Borkhardt, Arndt, Pandyra, Aleksandra A.
Publicado 2023

Single MHC‐I Expression Promotes Virus‐Induced Liver Immunopathology

por Xu, Haifeng C., Huang, Jun, Pandyra, Aleksandra A., Pandey, Piyush, Wang, Ruifeng, Zhang, Zeli, Zhuang, Yuan, Gertzen, Christoph G.W., Münk, Carsten, Herebian, Diran, Borkhardt, Arndt, Recher, Mike, Gohlke, Holger, Esposito, Irene, Oberbarnscheidt, Martin, Häussinger, Dieter, Lang, Karl S., Lang, Philipp A.
Publicado 2022

B Cell‐Mediated Maintenance of Cluster of Differentiation 169–Positive Cells Is Critical for Liver Regeneration

por Behnke, Kristina, Zhuang, Yuan, Xu, Haifeng C., Sundaram, Balamurugan, Reich, Maria, Shinde, Prashant V., Huang, Jun, Modares, Nastaran Fazel, Tumanov, Alexei V., Polz, Robin, Scheller, Jürgen, Ware, Carl F., Pfeffer, Klaus, Keitel, Verena, Häussinger, Dieter, Pandyra, Aleksandra A., Lang, Karl S., Lang, Philipp A.
Publicado 2018

BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment

por Liu, Wei, Stachura, Paweł, Xu, Haifeng C., Váraljai, Renáta, Shinde, Prashant, Ganesh, Nikkitha Umesh, Mack, Matthias, Van Lierop, Anke, Huang, Anfei, Sundaram, Balamurugan, Lang, Karl S., Picard, Daniel, Fischer, Ute, Remke, Marc, Homey, Bernhard, Roesch, Alexander, Häussinger, Dieter, Lang, Philipp A., Borkhardt, Arndt, Pandyra, Aleksandra A.
Publicado 2022

Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury

por Zhuang, Yuan, Xu, Haifeng C, Shinde, Prashant V, Warfsmann, Jens, Vasilevska, Jelena, Sundaram, Balamurugan, Behnke, Kristina, Huang, Jun, Hoell, Jessica I, Borkhardt, Arndt, Pfeffer, Klaus, Taha, Mohamed S, Herebian, Diran, Mayatepek, Ertan, Brenner, Dirk, Ahmadian, Mohammad Reza, Keitel, Verena, Wieczorek, Dagmar, Häussinger, Dieter, Pandyra, Aleksandra A, Lang, Karl S, Lang, Philipp A
Publicado 2020

NK Cells Regulate CD8(+) T Cell Mediated Autoimmunity

por Lang, Philipp A., Crome, Sarah Q., Xu, Haifeng C., Lang, Karl S., Chapatte, Laurence, Deenick, Elissa K., Grusdat, Melanie, Pandyra, Aleksandra A., Pozdeev, Vitaly I., Wang, Ruifeng, Holderried, Tobias A. W., Cantor, Harvey, Diefenbach, Andreas, Elford, Alisha R., McIlwain, David R., Recher, Mike, Häussinger, Dieter, Mak, Tak W., Ohashi, Pamela S.
Publicado 2020

Conjugated Bilirubin Triggers Anemia by Inducing Erythrocyte Death

por Lang, Elisabeth, Gatidis, Sergios, Freise, Noemi F, Bock, Hans, Kubitz, Ralf, Lauermann, Christian, Orth, Hans Martin, Klindt, Caroline, Schuier, Maximilian, Keitel, Verena, Reich, Maria, Liu, Guilai, Schmidt, Sebastian, Xu, Haifeng C, Qadri, Syed M, Herebian, Diran, Pandyra, Aleksandra A, Mayatepek, Ertan, Gulbins, Erich, Lang, Florian, Häussinger, Dieter, Lang, Karl S, Föller, Michael, Lang, Philipp A
Publicado 2015

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage

por Bhattacharya, Anannya, Hegazy, Ahmed N., Deigendesch, Nikolaus, Kosack, Lindsay, Cupovic, Jovana, Kandasamy, Richard K., Hildebrandt, Andrea, Merkler, Doron, Kühl, Anja A., Vilagos, Bojan, Schliehe, Christopher, Panse, Isabel, Khamina, Kseniya, Baazim, Hatoon, Arnold, Isabelle, Flatz, Lukas, Xu, Haifeng C., Lang, Philipp A., Aderem, Alan, Takaoka, Akinori, Superti-Furga, Giulio, Colinge, Jacques, Ludewig, Burkhard, Löhning, Max, Bergthaler, Andreas
Publicado 2015

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production

por Khairnar, Vishal, Duhan, Vikas, Maney, Sathish Kumar, Honke, Nadine, Shaabani, Namir, Pandyra, Aleksandra A., Seifert, Marc, Pozdeev, Vitaly, Xu, Haifeng C., Sharma, Piyush, Baldin, Fabian, Marquardsen, Florian, Merches, Katja, Lang, Elisabeth, Kirschning, Carsten, Westendorf, Astrid M., Häussinger, Dieter, Lang, Florian, Dittmer, Ulf, Küppers, Ralf, Recher, Mike, Hardt, Cornelia, Scheffrahn, Inka, Beauchemin, Nicole, Göthert, Joachim R., Singer, Bernhard B., Lang, Philipp A., Lang, Karl S.
Publicado 2015