One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade

por Xu, Xincheng, Chen, Zihong, Bartman, Caroline R., Xing, Xi, Olszewski, Kellen, Rabinowitz, Joshua D.
Publicado 2023

Methionine synthase supports tumor tetrahydrofolate pools

por Ghergurovich, Jonathan M., Xu, Xincheng, Wang, Joshua Z., Yang, Lifeng, Ryseck, Rolf-Peter, Wang, Lin, Rabinowitz, Joshua D.
Publicado 2021

Serine catabolism generates liver NADPH and supports hepatic lipogenesis

por Zhang, Zhaoyue, TeSlaa, Tara, Xu, Xincheng, Zeng, Xianfeng, Yang, Lifeng, Xing, Gang, Tesz, Gregory J, Clasquin, Michelle F, Rabinowitz, Joshua D
Publicado 2021

SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia

por García-Cañaveras, Juan C., Lancho, Olga, Ducker, Gregory S., Ghergurovich, Jonathan M., Xu, Xincheng, da Silva-Diz, Victoria, Minuzzo, Sonia, Indraccolo, Stefano, Kim, Hahn, Herranz, Daniel, Rabinowitz, Joshua D.
Publicado 2020