14-3-3 phosphorylation inhibits 14-3-3θ’s ability to regulate LRRK2 kinase activity

por Pattanayak, Rudradip, Petit, Chad M., Yacoubian, Talene A.
Publicado 2023

14-3-3theta Protects against Neurotoxicity in a Cellular Parkinson's Disease Model through Inhibition of the Apoptotic Factor Bax

por Slone, Sunny R., Lesort, Mathieu, Yacoubian, Talene A.
Publicado 2011

Dysregulation of 14‐3‐3 proteins in neurodegenerative diseases with Lewy body or Alzheimer pathology

por McFerrin, Michael B., Chi, Xiaofei, Cutter, Gary, Yacoubian, Talene A.
Publicado 2017

Defects in Very Long Chain Fatty Acid Synthesis Enhance Alpha-Synuclein Toxicity in a Yeast Model of Parkinson's Disease

por Lee, Yong Joo, Wang, Shaoxiao, Slone, Sunny R., Yacoubian, Talene A., Witt, Stephan N.
Publicado 2011

Angiogenin in Parkinson Disease Models: Role of Akt Phosphorylation and Evaluation of AAV-Mediated Angiogenin Expression in MPTP Treated Mice

por Steidinger, Trent U., Slone, Sunny R., Ding, Huiping, Standaert, David G., Yacoubian, Talene A.
Publicado 2013

14-3-3 mitigates alpha-synuclein aggregation and toxicity in the in vivo preformed fibril model

por Underwood, Rachel, Gannon, Mary, Pathak, Aneesh, Kapa, Navya, Chandra, Sidhanth, Klop, Alyssa, Yacoubian, Talene A.
Publicado 2021

Deletion in chromosome 6 spanning alpha-synuclein and multimerin1 loci in the Rab27a/b double knockout mouse

por Pattanayak, Rudradip, Underwood, Rachel, Crowley, Michael R., Crossman, David K., Morgan, Jennifer R., Yacoubian, Talene A.
Publicado 2022

Image Quantification for TSPO PET with a Novel Image-Derived Input Function Method

por Fang, Yu-Hua Dean, McConathy, Jonathan E., Yacoubian, Talene A., Zhang, Yue, Kennedy, Richard E., Standaert, David G.
Publicado 2022

CoQ10 in progressive supranuclear palsy: A randomized, placebo-controlled, double-blind trial

por Apetauerova, Diana, Scala, Stephanie A., Hamill, Robert W., Simon, David K., Pathak, Subash, Ruthazer, Robin, Standaert, David G., Yacoubian, Talene A.
Publicado 2016

14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer’s Disease Mouse Models

por Gannon, Mary, Wang, Bing, Stringfellow, Sara Anne, Quintin, Stephan, Mendoza, Itzel, Srikantha, Thanushri, Roberts, A. Claire, Saito, Takashi, Saido, Takaomi C., Roberson, Erik D., Yacoubian, Talene A.
Publicado 2022

Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease

por Carlisle, Samantha M., Qin, Hongwei, Hendrickson, R. Curtis, Muwanguzi, Jordana E., Lefkowitz, Elliot J., Kennedy, Richard E., Yan, Zhaoqi, Yacoubian, Talene A., Benveniste, Etty N., West, Andrew B., Harms, Ashley S., Standaert, David G.
Publicado 2021

Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain

por Xu, Enquan, Boddu, Ravindra, Abdelmotilib, Hisham A., Sokratian, Arpine, Kelly, Kaela, Liu, Zhiyong, Bryant, Nicole, Chandra, Sidhanth, Carlisle, Samantha M., Lefkowitz, Elliot J., Harms, Ashley S., Benveniste, Etty N., Yacoubian, Talene A., Volpicelli-Daley, Laura A., Standaert, David G., West, Andrew B.
Publicado 2022

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

por Qiao, Liyan, Hamamichi, Shusei, Caldwell, Kim A, Caldwell, Guy A, Yacoubian, Talene A, Wilson, Scott, Xie, Zuo-Lei, Speake, Lisa D, Parks, Rachael, Crabtree, Donna, Liang, Qiuli, Crimmins, Stephen, Schneider, Lonnie, Uchiyama, Yasuo, Iwatsubo, Takeshi, Zhou, Yi, Peng, Lisheng, Lu, YouMing, Standaert, David G, Walls, Ken C, Shacka, John J, Roth, Kevin A, Zhang, Jianhua
Publicado 2008