Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer

por Yaglom, Julia A., McFarland, Christopher, Mirny, Leonid, Sherman, Michael Y.
Publicado 2014

Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis

por Meng, Le, Hunt, Clayton, Yaglom, Julia A., Gabai, Vladimir L., Sherman, Michael Y.
Publicado 2011

Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module

por Patel, Shivani, Kumar, Santosh, Baldan, Simone, Hesin, Arkadi, Yaglom, Julia, Sherman, Michael Y.
Publicado 2022

Heat Shock Protein 70 Protects from Caspase-Independent Programmed Cell Death via Suppression of Stress Kinase JNK

por Gabai, Vladimir L., Meriin, Anatoli B., Yaglom, Julia A., Mosser, Dick D., Sherman, Michael Y.
Publicado 2001

Intracellular Aggregation of Polypeptides with Expanded Polyglutamine Domain Is Stimulated by Stress-Activated Kinase Mekk1

por Meriin, Anatoli B., Mabuchi, Katsuhide, Gabai, Vladimir L., Yaglom, Julia A., Kazantsev, Alex, Sherman, Michael Y.
Publicado 2001

A Cell Double-Barcoding System for Quantitative Evaluation of Primary Tumors and Metastasis in Animals That Uncovers Clonal-Specific Anti-Cancer Drug Effects

por Hesin, Arkadi, Kumar, Santosh, Gahramanov, Valid, Becker, Maria, Vilenchik, Maria, Alexandrov, Ilya, Yaglom, Julia, Sherman, Michael Y.
Publicado 2022

Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations

por Yaglom, Julia A., Wang, Yongmei, Li, Amy, Li, Zhenghu, Monti, Stephano, Alexandrov, Ilya, Lu, Xiongbin, Sherman, Michael Y.
Publicado 2018

Author Correction: Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations

por Yaglom, Julia A., Wang, Yongmei, Li, Amy, Li, Zhenghu, Monti, Stephano, Alexandrov, Ilya, Lu, Xiongbin, Sherman, Michael Y.
Publicado 2018

Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks

por Kumar, Santosh, Gahramanov, Valid, Patel, Shivani, Yaglom, Julia, Kaczmarczyk, Lukasz, Alexandrov, Ivan A., Gerlitz, Gabi, Salmon-Divon, Mali, Sherman, Michael Y.
Publicado 2023

Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity

por Igwebuike, Chinaemere, Yaglom, Julia, Huiting, Leah, Feng, Hui, Campbell, Joshua D., Wang, Zhiyong, Havasi, Andrea, Pimentel, David, Sherman, Michael Y., Borkan, Steven C.
Publicado 2020

Search for Synergistic Drug Combinations to Treat Chronic Lymphocytic Leukemia

por Hezkiy, Eleonora Ela, Kumar, Santosh, Gahramanov, Valid, Yaglom, Julia, Hesin, Arkadi, Jadhav, Suchita Suryakant, Guzev, Ekaterina, Patel, Shivani, Avinery, Elena, Firer, Michael A., Sherman, Michael Y.
Publicado 2022