Germline contamination and leakage in whole genome somatic single nucleotide variant detection

por Sendorek, Dorota H., Caloian, Cristian, Ellrott, Kyle, Bare, J. Christopher, Yamaguchi, Takafumi N., Ewing, Adam D., Houlahan, Kathleen E., Norman, Thea C., Margolin, Adam A., Stuart, Joshua M., Boutros, Paul C.
Publicado 2018

Valection: design optimization for validation and verification studies

por Cooper, Christopher I, Yao, Delia, Sendorek, Dorota H, Yamaguchi, Takafumi N, P’ng, Christine, Houlahan, Kathleen E, Caloian, Cristian, Fraser, Michael, Ellrott, Kyle, Margolin, Adam A, Bristow, Robert G, Stuart, Joshua M, Boutros, Paul C
Publicado 2018

Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations

por Böttcher, René, Kweldam, Charlotte F., Livingstone, Julie, Lalonde, Emilie, Yamaguchi, Takafumi N., Huang, Vincent, Yousif, Fouad, Fraser, Michael, Bristow, Robert G., van der Kwast, Theodorus, Boutros, Paul C., Jenster, Guido, van Leenders, Geert J. L. H.
Publicado 2018

The telomere length landscape of prostate cancer

por Livingstone, Julie, Shiah, Yu-Jia, Yamaguchi, Takafumi N., Heisler, Lawrence E., Huang, Vincent, Lesurf, Robert, Gebo, Tsumugi, Carlin, Benjamin, Eng, Stefan, Drysdale, Erik, Green, Jeffrey, van der Kwast, Theodorus, Bristow, Robert G., Fraser, Michael, Boutros, Paul C.
Publicado 2021

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

por Ewing, Adam D, Houlahan, Kathleen E, Hu, Yin, Ellrott, Kyle, Caloian, Cristian, Yamaguchi, Takafumi N, Bare, J Christopher, P’ng, Christine, Waggott, Daryl, Sabelnykova, Veronica Y, Kellen, Michael R, Norman, Thea C, Haussler, David, Friend, Stephen H, Stolovitzky, Gustavo, Margolin, Adam A, Stuart, Joshua M, Boutros, Paul C
Publicado 2015

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

por Lee, Anna Y., Ewing, Adam D., Ellrott, Kyle, Hu, Yin, Houlahan, Kathleen E., Bare, J. Christopher, Espiritu, Shadrielle Melijah G., Huang, Vincent, Dang, Kristen, Chong, Zechen, Caloian, Cristian, Yamaguchi, Takafumi N., Kellen, Michael R., Chen, Ken, Norman, Thea C., Friend, Stephen H., Guinney, Justin, Stolovitzky, Gustavo, Haussler, David, Margolin, Adam A., Stuart, Joshua M., Boutros, Paul C.
Publicado 2018

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

por van Dessel, Lisanne F., van Riet, Job, Smits, Minke, Zhu, Yanyun, Hamberg, Paul, van der Heijden, Michiel S., Bergman, Andries M., van Oort, Inge M., de Wit, Ronald, Voest, Emile E., Steeghs, Neeltje, Yamaguchi, Takafumi N., Livingstone, Julie, Boutros, Paul C., Martens, John W. M., Sleijfer, Stefan, Cuppen, Edwin, Zwart, Wilbert, van de Werken, Harmen J. G., Mehra, Niven, Lolkema, Martijn P.
Publicado 2019

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories

por Taylor, Renea A., Fraser, Michael, Livingstone, Julie, Espiritu, Shadrielle Melijah G., Thorne, Heather, Huang, Vincent, Lo, Winnie, Shiah, Yu-Jia, Yamaguchi, Takafumi N., Sliwinski, Ania, Horsburgh, Sheri, Meng, Alice, Heisler, Lawrence E., Yu, Nancy, Yousif, Fouad, Papargiris, Melissa, Lawrence, Mitchell G., Timms, Lee, Murphy, Declan G., Frydenberg, Mark, Hopkins, Julia F., Bolton, Damien, Clouston, David, McPherson, John D., van der Kwast, Theodorus, Boutros, Paul C., Risbridger, Gail P., Bristow, Robert G.
Publicado 2017

Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer

por Zhou, Stanley, Hawley, James R., Soares, Fraser, Grillo, Giacomo, Teng, Mona, Madani Tonekaboni, Seyed Ali, Hua, Junjie Tony, Kron, Ken J., Mazrooei, Parisa, Ahmed, Musaddeque, Arlidge, Christopher, Yun, Hwa Young, Livingstone, Julie, Huang, Vincent, Yamaguchi, Takafumi N., Espiritu, Shadrielle M. G., Zhu, Yanyun, Severson, Tesa M., Murison, Alex, Cameron, Sarina, Zwart, Wilbert, van der Kwast, Theodorus, Pugh, Trevor J., Fraser, Michael, Boutros, Paul C., Bristow, Robert G., He, Housheng Hansen, Lupien, Mathieu
Publicado 2020

Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial

por Nassiri, Farshad, Patil, Vikas, Yefet, Leeor S., Singh, Olivia, Liu, Jeff, Dang, Rachel M. A., Yamaguchi, Takafumi N., Daras, Mariza, Cloughesy, Timothy F., Colman, Howard, Kumthekar, Priya U., Chen, Clark C., Aiken, Robert, Groves, Morris D., Ong, Shirley S., Ramakrishna, Rohan, Vogelbaum, Michael A., Khagi, Simon, Kaley, Thomas, Melear, Jason M., Peereboom, David M., Rodriguez, Analiz, Yankelevich, Maxim, Nair, Suresh G., Puduvalli, Vinay K., Aldape, Kenneth, Gao, Andrew, López-Janeiro, Álvaro, de Andrea, Carlos E., Alonso, Marta M., Boutros, Paul, Robbins, Joan, Mason, Warren P., Sonabend, Adam M., Stupp, Roger, Fueyo, Juan, Gomez-Manzano, Candelaria, Lang, Frederick F., Zadeh, Gelareh
Publicado 2023

Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy

por Wedge, Marie-Eve, Jennings, Victoria A., Crupi, Mathieu J. F., Poutou, Joanna, Jamieson, Taylor, Pelin, Adrian, Pugliese, Giuseppe, de Souza, Christiano Tanese, Petryk, Julia, Laight, Brian J., Boileau, Meaghan, Taha, Zaid, Alluqmani, Nouf, McKay, Hayley E., Pikor, Larissa, Khan, Sarwat Tahsin, Azad, Taha, Rezaei, Reza, Austin, Bradley, He, Xiaohong, Mansfield, David, Rose, Elaine, Brown, Emily E. F., Crawford, Natalie, Alkayyal, Almohanad, Surendran, Abera, Singaravelu, Ragunath, Roy, Dominic G., Migneco, Gemma, McSweeney, Benjamin, Cottee, Mary Lynn, Jacobus, Egon J., Keller, Brian A., Yamaguchi, Takafumi N., Boutros, Paul C., Geoffrion, Michele, Rayner, Katey J., Chatterjee, Avijit, Auer, Rebecca C., Diallo, Jean-Simon, Gibbings, Derrick, tenOever, Benjamin R., Melcher, Alan, Bell, John C., Ilkow, Carolina S.
Publicado 2022

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

por Alioto, Tyler S., Buchhalter, Ivo, Derdak, Sophia, Hutter, Barbara, Eldridge, Matthew D., Hovig, Eivind, Heisler, Lawrence E., Beck, Timothy A., Simpson, Jared T., Tonon, Laurie, Sertier, Anne-Sophie, Patch, Ann-Marie, Jäger, Natalie, Ginsbach, Philip, Drews, Ruben, Paramasivam, Nagarajan, Kabbe, Rolf, Chotewutmontri, Sasithorn, Diessl, Nicolle, Previti, Christopher, Schmidt, Sabine, Brors, Benedikt, Feuerbach, Lars, Heinold, Michael, Gröbner, Susanne, Korshunov, Andrey, Tarpey, Patrick S., Butler, Adam P., Hinton, Jonathan, Jones, David, Menzies, Andrew, Raine, Keiran, Shepherd, Rebecca, Stebbings, Lucy, Teague, Jon W., Ribeca, Paolo, Giner, Francesc Castro, Beltran, Sergi, Raineri, Emanuele, Dabad, Marc, Heath, Simon C., Gut, Marta, Denroche, Robert E., Harding, Nicholas J., Yamaguchi, Takafumi N., Fujimoto, Akihiro, Nakagawa, Hidewaki, Quesada, Víctor, Valdés-Mas, Rafael, Nakken, Sigve, Vodák, Daniel, Bower, Lawrence, Lynch, Andrew G., Anderson, Charlotte L., Waddell, Nicola, Pearson, John V., Grimmond, Sean M., Peto, Myron, Spellman, Paul, He, Minghui, Kandoth, Cyriac, Lee, Semin, Zhang, John, Létourneau, Louis, Ma, Singer, Seth, Sahil, Torrents, David, Xi, Liu, Wheeler, David A., López-Otín, Carlos, Campo, Elías, Campbell, Peter J., Boutros, Paul C., Puente, Xose S., Gerhard, Daniela S., Pfister, Stefan M., McPherson, John D., Hudson, Thomas J., Schlesner, Matthias, Lichter, Peter, Eils, Roland, Jones, David T. W., Gut, Ivo G.
Publicado 2015

Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative

por Butler-Laporte, Guillaume, Povysil, Gundula, Kosmicki, Jack A., Cirulli, Elizabeth T., Drivas, Theodore, Furini, Simone, Saad, Chadi, Schmidt, Axel, Olszewski, Pawel, Korotko, Urszula, Quinodoz, Mathieu, Çelik, Elifnaz, Kundu, Kousik, Walter, Klaudia, Jung, Junghyun, Stockwell, Amy D., Sloofman, Laura G., Jordan, Daniel M., Thompson, Ryan C., Del Valle, Diane, Simons, Nicole, Cheng, Esther, Sebra, Robert, Schadt, Eric E., Kim-Schulze, Seunghee, Gnjatic, Sacha, Merad, Miriam, Buxbaum, Joseph D., Beckmann, Noam D., Charney, Alexander W., Przychodzen, Bartlomiej, Chang, Timothy, Pottinger, Tess D., Shang, Ning, Brand, Fabian, Fava, Francesca, Mari, Francesca, Chwialkowska, Karolina, Niemira, Magdalena, Pula, Szymon, Baillie, J Kenneth, Stuckey, Alex, Salas, Antonio, Bello, Xabier, Pardo-Seco, Jacobo, Gómez-Carballa, Alberto, Rivero-Calle, Irene, Martinón-Torres, Federico, Ganna, Andrea, Karczewski, Konrad J., Veerapen, Kumar, Bourgey, Mathieu, Bourque, Guillaume, Eveleigh, Robert JM, Forgetta, Vincenzo, Morrison, David, Langlais, David, Lathrop, Mark, Mooser, Vincent, Nakanishi, Tomoko, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklos, Marincevic-Zuniga, Yanara, Nordlund, Jessica, Schiabor Barrett, Kelly M., Lee, William, Bolze, Alexandre, White, Simon, Riffle, Stephen, Tanudjaja, Francisco, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Casadei, Nicolas, Motameny, Susanne, Alaamery, Manal, Massadeh, Salam, Aljawini, Nora, Almutairi, Mansour S., Arabi, Yaseen M., Alqahtani, Saleh A., Al Harthi, Fawz S., Almutairi, Amal, Alqubaishi, Fatima, Alotaibi, Sarah, Binowayn, Albandari, Alsolm, Ebtehal A., El Bardisy, Hadeel, Fawzy, Mohammad, Cai, Fang, Soranzo, Nicole, Butterworth, Adam, Geschwind, Daniel H., Arteaga, Stephanie, Stephens, Alexis, Butte, Manish J., Boutros, Paul C., Yamaguchi, Takafumi N., Tao, Shu, Eng, Stefan, Sanders, Timothy, Tung, Paul J., Broudy, Michael E., Pan, Yu, Gonzalez, Alfredo, Chavan, Nikhil, Johnson, Ruth, Pasaniuc, Bogdan, Yaspan, Brian, Smieszek, Sandra, Rivolta, Carlo, Bibert, Stephanie, Bochud, Pierre-Yves, Dabrowski, Maciej, Zawadzki, Pawel, Sypniewski, Mateusz, Kaja, Elżbieta, Chariyavilaskul, Pajaree, Nilaratanakul, Voraphoj, Hirankarn, Nattiya, Shotelersuk, Vorasuk, Pongpanich, Monnat, Phokaew, Chureerat, Chetruengchai, Wanna, Tokunaga, Katsushi, Sugiyama, Masaya, Kawai, Yosuke, Hasegawa, Takanori, Naito, Tatsuhiko, Namkoong, Ho, Edahiro, Ryuya, Kimura, Akinori, Ogawa, Seishi, Kanai, Takanori, Fukunaga, Koichi, Okada, Yukinori, Imoto, Seiya, Miyano, Satoru, Mangul, Serghei, Abedalthagafi, Malak S., Zeberg, Hugo, Grzymski, Joseph J., Washington, Nicole L., Ossowski, Stephan, Ludwig, Kerstin U., Schulte, Eva C., Riess, Olaf, Moniuszko, Marcin, Kwasniewski, Miroslaw, Mbarek, Hamdi, Ismail, Said I., Verma, Anurag, Goldstein, David B., Kiryluk, Krzysztof, Renieri, Alessandra, Ferreira, Manuel A. R., Richards, J Brent
Publicado 2022