Recent Advancements in Development and Therapeutic Applications of Genome-Targeting Triplex-Forming Oligonucleotides and Peptide Nucleic Acids

por Mikame, Yu, Yamayoshi, Asako
Publicado 2023

Recent Advances in the Delivery Carriers and Chemical Conjugation Strategies for Nucleic Acid Drugs

por Oyama, Shota, Yamamoto, Tsuyoshi, Yamayoshi, Asako
Publicado 2021

Chemistry of Therapeutic Oligonucleotides That Drives Interactions with Biomolecules

por Terada, Chisato, Kawamoto, Seiya, Yamayoshi, Asako, Yamamoto, Tsuyoshi
Publicado 2022

Investigation of enhanced intracellular delivery of nanomaterials modified with novel cell-penetrating zwitterionic peptide-lipid derivatives

por Sugimoto, Yuri, Suga, Tadaharu, Umino, Mizuki, Yamayoshi, Asako, Mukai, Hidefumi, Kawakami, Shigeru
Publicado 2023

Successful Incorporation of Exosome-Capturing Antibody-siRNA Complexes into Multiple Myeloma Cells and Suppression of Targeted mRNA Transcripts

por Soma, Emi, Yamayoshi, Asako, Toda, Yuki, Mishima, Yuji, Hosogi, Shigekuni, Ashihara, Eishi
Publicado 2022

Understanding In Vivo Fate of Nucleic Acid and Gene Medicines for the Rational Design of Drugs

por Fumoto, Shintaro, Yamamoto, Tsuyoshi, Okami, Kazuya, Maemura, Yuina, Terada, Chisato, Yamayoshi, Asako, Nishida, Koyo
Publicado 2021

Microfluidic Post-Insertion Method for the Efficient Preparation of PEGylated Liposomes Using High Functionality and Quality Lipids

por Sugimoto, Yuri, Suga, Tadaharu, Kato, Naoya, Umino, Mizuki, Yamayoshi, Asako, Mukai, Hidefumi, Kawakami, Shigeru
Publicado 2022

Highly Potent GalNAc-Conjugated Tiny LNA Anti-miRNA-122 Antisense Oligonucleotides

por Yamamoto, Tsuyoshi, Mukai, Yahiro, Wada, Fumito, Terada, Chisato, Kayaba, Yukina, Oh, Kaho, Yamayoshi, Asako, Obika, Satoshi, Harada–Shiba, Mariko
Publicado 2021

Development of Antibody–Oligonucleotide Complexes for Targeting Exosomal MicroRNA

por Yamayoshi, Asako, Oyama, Shota, Kishimoto, Yusuke, Konishi, Ryo, Yamamoto, Tsuyoshi, Kobori, Akio, Harada, Hiroshi, Ashihara, Eishi, Sugiyama, Hiroshi, Murakami, Akira
Publicado 2020

Dynamic and static control of the off-target interactions of antisense oligonucleotides using toehold chemistry

por Terada, Chisato, Oh, Kaho, Tsubaki, Ryutaro, Chan, Bun, Aibara, Nozomi, Ohyama, Kaname, Shibata, Masa-Aki, Wada, Takehiko, Harada-Shiba, Mariko, Yamayoshi, Asako, Yamamoto, Tsuyoshi
Publicado 2023

Drug discovery and development scheme for liver-targeting bridged nucleic acid antisense oligonucleotides

por Wada, Fumito, Yamamoto, Tsuyoshi, Kobayashi, Tadayuki, Tachibana, Keisuke, Ito, Kosuke Ramon, Hamasaki, Mayumi, Kayaba, Yukina, Terada, Chisato, Yamayoshi, Asako, Obika, Satoshi, Harada-Shiba, Mariko
Publicado 2021