ACE2, B(0)AT1, and SARS-CoV-2 spike protein: Structural and functional implications

por Zhang, Yuanyuan, Yan, Renhong, Zhou, Qiang
Publicado 2022

Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant

por Li, Yaning, Shen, Yaping, Hu, Ziwei, Yan, Renhong
Publicado 2023

Structural Basis for the Enhanced Infectivity and Immune Evasion of Omicron Subvariants

por Li, Yaning, Shen, Yaping, Zhang, Yuanyuan, Yan, Renhong
Publicado 2023

Structural insight into the substrate recognition and transport mechanism of the human LAT2–4F2hc complex

por Yan, Renhong, Zhou, Jiayao, Li, Yaning, Lei, Jianlin, Zhou, Qiang
Publicado 2020

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

por Yan, Renhong, Zhang, Yuanyuan, Li, Yaning, Xia, Lu, Guo, Yingying, Zhou, Qiang
Publicado 2020

Structures of ACE2–SIT1 recognized by Omicron variants of SARS-CoV-2

por Shen, Yaping, Wang, Jianhui, Li, Yaning, Zhang, Yuanyuan, Tian, Ruilin, Yan, Renhong
Publicado 2022

Cryo-EM structure of the human heteromeric amino acid transporter b(0,+)AT-rBAT

por Yan, Renhong, Li, Yaning, Shi, Yi, Zhou, Jiayao, Lei, Jianlin, Huang, Jing, Zhou, Qiang
Publicado 2020

Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B(0)AT1 and ACE2-SIT1

por Li, Yaning, Chen, Yiming, Zhang, Yuanyuan, Shen, Yaping, Xu, Kangtai, Liu, Yaqi, Wang, Zilong, Yan, Renhong
Publicado 2023

Cryo-EM structures of SARS-CoV-2 BA.2-derived subvariants spike in complex with ACE2 receptor

por Li, Yaning, Ren, Chang, Shen, Yaping, Zhang, Yuanyuan, Chen, Jin, Zheng, Jiangnan, Tian, Ruijun, Cao, Liwei, Yan, Renhong
Publicado 2023

Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2

por Yan, Renhong, Zhang, Yuanyuan, Li, Yaning, Ye, Fangfei, Guo, Yingying, Xia, Lu, Zhong, Xinyue, Chi, Ximin, Zhou, Qiang
Publicado 2021

Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states

por Guo, Yingying, Zhang, Yuanyuan, Yan, Renhong, Huang, Bangdong, Ye, Fangfei, Wu, Liushu, Chi, Ximin, shi, Yi, Zhou, Qiang
Publicado 2022

Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter

por Yan, Renhong, Li, Yaning, Müller, Jennifer, Zhang, Yuanyuan, Singer, Simon, Xia, Lu, Zhong, Xinyue, Gertsch, Jürg, Altmann, Karl-Heinz, Zhou, Qiang
Publicado 2021

Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants

por Li, Yaning, Fan, Qing, Zhou, Bing, Shen, Yaping, Zhang, Yuanyuan, Cheng, Lin, Qi, Furong, Song, Shuo, Guo, Yingying, Yan, Renhong, Ju, Bin, Zhang, Zheng
Publicado 2022

The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis

por Yan, Renhong, Xie, Enjun, Li, Yaning, Li, Jin, Zhang, Yuanyuan, Chi, Ximin, Hu, Xueping, Xu, Lei, Hou, Tingjun, Stockwell, Brent R., Min, Junxia, Zhou, Qiang, Wang, Fudi
Publicado 2022

Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection

por Guo, Liang, Bi, Wenwen, Wang, Xinling, Xu, Wei, Yan, Renhong, Zhang, Yuanyuan, Zhao, Kai, Li, Yaning, Zhang, Mingfeng, Cai, Xia, Jiang, Shibo, Xie, Youhua, Zhou, Qiang, Lu, Lu, Dang, Bobo
Publicado 2020

A high-throughput fully automatic biosensing platform for efficient COVID-19 detection

por Rong, Guoguang, Zheng, Yuqiao, Li, Xiangqing, Guo, Mengzhun, Su, Yi, Bian, Sumin, Dang, Bobo, Chen, Yin, Zhang, Yanjun, Shen, Linhai, Jin, Hui, Yan, Renhong, Wen, Liaoyong, Zhu, Peixi, Sawan, Mohamad
Publicado 2023

ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker

por Chen, Yuning, Zhang, Ya-Nan, Yan, Renhong, Wang, Guifeng, Zhang, Yuanyuan, Zhang, Zhe-Rui, Li, Yaning, Ou, Jianxia, Chu, Wendi, Liang, Zhijuan, Wang, Yongmei, Chen, Yi-Li, Chen, Ganjun, Wang, Qi, Zhou, Qiang, Zhang, Bo, Wang, Chunhe
Publicado 2021

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2

por Chi, Xiangyang, Yan, Renhong, Zhang, Jun, Zhang, Guanying, Zhang, Yuanyuan, Hao, Meng, Zhang, Zhe, Fan, Pengfei, Dong, Yunzhu, Yang, Yilong, Chen, Zhengshan, Guo, Yingying, Zhang, Jinlong, Li, Yaning, Song, Xiaohong, Chen, Yi, Xia, Lu, Fu, Ling, Hou, Lihua, Xu, Junjie, Yu, Changming, Li, Jianmin, Zhou, Qiang, Chen, Wei
Publicado 2020

Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies

por Yan, Renhong, Wang, Ruoke, Ju, Bin, Yu, Jinfang, Zhang, Yuanyuan, Liu, Nan, Wang, Jia, Zhang, Qi, Chen, Peng, Zhou, Bing, Li, Yaning, Shen, Yaping, Zhang, Shuyuan, Tian, Long, Guo, Yingying, Xia, Lu, Zhong, Xinyue, Cheng, Lin, Ge, Xiangyang, Zhao, Juanjuan, Wang, Hong-Wei, Wang, Xinquan, Zhang, Zheng, Zhang, Linqi, Zhou, Qiang
Publicado 2021

Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses

por Wang, Yingdan, Liu, Meiqin, Shen, Yaping, Ma, Yunping, Li, Xiang, Zhang, Yuanyuan, Liu, Mei, Yang, Xing-Lou, Chen, Jun, Yan, Renhong, Luan, Die, Wang, Yanqun, Chen, Ying, Wang, Qimin, Lin, Haofeng, Li, Yaning, Wu, Kaiyue, Zhu, Tongyu, Zhao, Jincun, Lu, Hongzhou, Wen, Yumei, Jiang, Shibo, Wu, Fan, Zhou, Qiang, Shi, Zheng-Li, Huang, Jinghe
Publicado 2022