Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment

por Yan, Victoria C., Muller, Florian L.
Publicado 2020

Remdesivir for COVID-19: Why Not Dose Higher?

por Yan, Victoria C., Muller, Florian L.
Publicado 2021

Single-Cell RNA Sequencing Supports Preferential Bioactivation of Remdesivir in the Liver

por Yan, Victoria C., Muller, Florian L.
Publicado 2021

Why Remdesivir Failed: Preclinical Assumptions Overestimate the Clinical Efficacy of Remdesivir for COVID-19 and Ebola

por Yan, Victoria C., Muller, Florian L.
Publicado 2021

Publisher Correction: A condensate dynamic instability orchestrates actomyosin cortex activation

por Yan, Victoria Tianjing, Narayanan, Arjun, Wiegand, Tina, Jülicher, Frank, Grill, Stephan W.
Publicado 2023

A condensate dynamic instability orchestrates actomyosin cortex activation

por Yan, Victoria Tianjing, Narayanan, Arjun, Wiegand, Tina, Jülicher, Frank, Grill, Stephan W.
Publicado 2022

Role of α-Catenin and its mechanosensing properties in regulating Hippo/YAP-dependent tissue growth

por Sarpal, Ritu, Yan, Victoria, Kazakova, Lidia, Sheppard, Luka, Yu, Jessica C., Fernandez-Gonzalez, Rodrigo, Tepass, Ulrich
Publicado 2019

Single-molecule imaging reveals that Z ring condensation is essential for cell division in Bacillus subtilis

por Squyres, Georgia R., Holmes, Matthew J., Barger, Sarah R., Pennycook, Betheney R., Ryan, Joel, Yan, Victoria T., Garner, Ethan C.
Publicado 2021

Robust detection of oncometabolic aberrations by (1)H–(13)C heteronuclear single quantum correlation in intact biological specimens

por Barekatain, Yasaman, Yan, Victoria C., Arthur, Kenisha, Ackroyd, Jeffrey J., Khadka, Sunada, De Groot, John, Huse, Jason T., Muller, Florian L.
Publicado 2020

Environmental Lead Exposure and Influenza and Respiratory Syncytial Virus Diagnoses in Young Children: A Test-Negative Case-Control Study

por Oktapodas Feiler, Marina, Caserta, Mary T., van Wijngaarden, Edwin, Thevenet-Morrison, Kelly, Hardy, Dwight J., Zhang, Yan Victoria, Dozier, Ann M., Lawrence, B. Paige, Jusko, Todd A.
Publicado 2020

Targeting Host Glycolysis as a Strategy for Antimalarial Development

por Jezewski, Andrew J., Lin, Yu-Hsi, Reisz, Julie A., Culp-Hill, Rachel, Barekatain, Yasaman, Yan, Victoria C., D’Alessandro, Angelo, Muller, Florian L., Odom John, Audrey R.
Publicado 2021

The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues

por Pisaneschi, Federica, Lin, Yu-Hsi, Leonard, Paul G., Satani, Nikunj, Yan, Victoria C., Hammoudi, Naima, Raghavan, Sudhir, Link, Todd M., K. Georgiou, Dimitra, Czako, Barbara, Muller, Florian L.
Publicado 2019

An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesiv...

por Cook, Sarah, Wittenburg, Luke, Yan, Victoria C., Theil, Jacob H., Castillo, Diego, Reagan, Krystle L., Williams, Sonyia, Pham, Cong-Dat, Li, Chun, Muller, Florian L., Murphy, Brian G.
Publicado 2022

T Cell Responses Correlate with Self-Reported Disease Severity and Neutralizing Antibody Responses Predict Protection against SARS-CoV-2 Breakthrough Infection

por Zhao, Zhen, Kumanovics, Attila, Love, Tanzy, Melanson, Stacy E. F., Meng, Qing H., Wu, Alan H. B., Wiencek, Joesph, Apple, Fred S., Ondracek, Caitlin R., Koch, David D., Christenson, Robert H., Zhang, Yan Victoria
Publicado 2023

Pharmacokinetics of Orally Administered GS-441524 in Dogs

por Yan, Victoria C., Pham, Cong-Dat, Yan, Matthew J., Yan, Alexander J., Khadka, Sunada, Arthur, Kenisha, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Roon, Laura E., Bushman, Lane R., Anderson, Peter L., Li, Chun, Muller, Florian L.
Publicado 2021

Enolase Inhibitors as Early Lead Therapeutics against Trypanosoma brucei

por Roster, Colm P., LaVigne, Danielle, Milanes, Jillian E., Knight, Emily, Anderson, Heidi D., Pizarro, Sabrina, Harding, Elijah M., Morris, Meredith T., Yan, Victoria C., Pham, Cong-Dat, Muller, Florian, Kwain, Samuel, Rees, Kerrick C., Dominy, Brian, Whitehead, Daniel C., Uddin, Md Nasir, Millward, Steven W., Morris, James C.
Publicado 2023

Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers

por Yan, Victoria C., Pham, Cong-Dat, Ballato, Elliot S., Yang, Kristine L., Arthur, Kenisha, Khadka, Sunada, Barekatain, Yasaman, Shrestha, Prakriti, Tran, Theresa, Poral, Anton H., Washington, Mykia, Raghavan, Sudhir, Czako, Barbara, Pisaneschi, Federica, Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Millward, Steven W., Muller, Florian L.
Publicado 2022

Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism

por Khadka, Sunada, Lin, Yu-Hsi, Ackroyd, Jeffrey, Chen, Yi-An, Sheng, Yanghui, Qian, Wubin, Guo, Sheng, Chen, Yining, Behr, Eliot, Barekatain, Yasaman, Uddin, Nasir, Arthur, Kenisha, Yan, Victoria, Hsu, Wen-Hao, Chang, Qing, Poral, Anton, Tran, Theresa, Chaurasia, Surendra, Georgiou, Dimitra K., Asara, John M., Barthel, Floris P., Millward, Steve W., DePinho, Ronald A., Muller, Florian L.
Publicado 2023

Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine

por Barekatain, Yasaman, Ackroyd, Jeffrey J., Yan, Victoria C., Khadka, Sunada, Wang, Lin, Chen, Ko-Chien, Poral, Anton H., Tran, Theresa, Georgiou, Dimitra K., Arthur, Kenisha, Lin, Yu-Hsi, Satani, Nikunj, Ballato, Elliot S., Behr, Eliot I., deCarvalho, Ana C., Verhaak, Roel G. W., de Groot, John, Huse, Jason T., Asara, John M., Kalluri, Raghu, Muller, Florian L.
Publicado 2021

An Enolase Inhibitor for the Targeted Treatment of ENO1-Deleted Cancers

por Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Yan, Victoria C., Barekatain, Yasaman, Khadka, Sunada, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Pham, Cong-Dat, Arthur, Kenisha, Maxwell, David, Peng, Zhenghong, Leonard, Paul G., Czako, Barbara, Pisaneschi, Federica, Mandal, Pijus, Sun, Yuting, Zielinski, Rafal, Pando, Susana Castro, Wang, Xiaobo, Tran, Theresa, Xu, Quanyu, Wu, Qi, Jiang, Yongying, Kang, Zhijun, Asara, John M., Priebe, Waldemar, Bornmann, William, Marszalek, Joseph R., DePinho, Ronald A., Muller, Florian L.
Publicado 2020