Bcl‐2/Bcl‐xl inhibitor APG‐1252‐M1 is a promising therapeutic strategy for gastric carcinoma

por Yi, Hanjie, Qiu, Miao‐Zhen, Yuan, Luping, Luo, Qiuyun, Pan, Wentao, Zhou, Suna, Zhang, Lin, Yan, Xianglei, Yang, Da‐Jun
Publicado 2020

A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma

por Yi, Hanjie, Yan, Xianglei, Luo, Qiuyun, Yuan, Luping, Li, Baoxia, Pan, Wentao, Zhang, Lin, Chen, Haibo, Wang, Jing, Zhang, Yubin, Zhai, Yifan, Qiu, Miao-Zhen, Yang, Da-Jun
Publicado 2018

Cell targeting and immunostimulatory properties of a novel Fcγ-receptor-independent agonistic anti-CD40 antibody in rhesus macaques

por Yan, Xianglei, Ols, Sebastian, Arcoverde Cerveira, Rodrigo, Lenart, Klara, Hellgren, Fredrika, Ye, Kewei, Cagigi, Alberto, Buggert, Marcus, Nimmerjahn, Falk, Falkesgaard Højen, Jesper, Parera, Daniel, Pessara, Ulrich, Fischer, Stephan, Loré, Karin
Publicado 2023

A Novel BCL-2 Inhibitor APG-2575 Exerts Synthetic Lethality With BTK or MDM2-p53 Inhibitor in Diffuse Large B-Cell Lymphoma

por Luo, Qiuyun, Pan, Wentao, Zhou, Suna, Wang, Guangfeng, Yi, Hanjie, Zhang, Lin, Yan, Xianglei, Yuan, Luping, Liu, Zhenyi, Wang, Jing, Chen, Haibo, Qiu, MiaoZhen, Yang, DaJun, Sun, Jian
Publicado 2020

A third dose of the unmodified COVID-19 mRNA vaccine CVnCoV enhances quality and quantity of immune responses

por Lenart, Klara, Hellgren, Fredrika, Ols, Sebastian, Yan, Xianglei, Cagigi, Alberto, Cerveira, Rodrigo Arcoverde, Winge, Inga, Hanczak, Jakub, Mueller, Stefan O., Jasny, Edith, Schwendt, Kim, Rauch, Susanne, Petsch, Benjamin, Loré, Karin
Publicado 2022

Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells

por Chen, Haibo, Luo, Dingyuan, Zhang, Lin, Lin, Xiaofeng, Luo, Qiuyun, Yi, Hanjie, Wang, Jing, Yan, Xianglei, Li, Baoxia, Chen, Yuelei, Liu, Xingguang, Zhang, Hong, Liu, Sheng, Qiu, Miaozhen, Yang, Dajun, Jiang, Ningyi
Publicado 2017

Preclinical development of HQP1351, a multikinase inhibitor targeting a broad spectrum of mutant KIT kinases, for the treatment of imatinib-resistant gastrointestinal stromal tumor...

por Liu, Xuechao, Wang, Guangfeng, Yan, Xianglei, Qiu, Haibo, Min, Ping, Wu, Miaoyi, Tang, Chunyang, Zhang, Fei, Tang, Qiuqiong, Zhu, Saijie, Qiu, Miaozhen, Zhuang, Wei, Fang, Douglas D., Zhou, Zhiwei, Yang, Dajun, Zhai, Yifan
Publicado 2019