Distinct Domains of Musk Mediate Its Abilities to Induce and to Associate with Postsynaptic Specializations

por Zhou, Heather, Glass, David J., Yancopoulos, George D., Sanes, Joshua R.
Publicado 1999

Glucagon contributes to liver zonation

por Cheng, Xiping, Kim, Sun Y., Okamoto, Haruka, Xin, Yurong, Yancopoulos, George D., Murphy, Andrew J., Gromada, Jesper
Publicado 2018

A first‐in‐human pharmacodynamic and pharmacokinetic study of a fully human anti‐glucagon receptor monoclonal antibody in normal healthy volunteers

por Kostic, Ana, King, Thomas Alexander, Yang, Feng, Chan, Kuo‐Chen, Yancopoulos, George D., Gromada, Jesper, Harp, Joyce B.
Publicado 2017

Rapid decrease in tumor perfusion following VEGF blockade predicts long-term tumor growth inhibition in preclinical tumor models

por Eichten, Alexandra, Adler, Alexander P., Cooper, Blerta, Griffith, Jennifer, Wei, Yi, Yancopoulos, George D., Lin, Hsin Chieh, Thurston, Gavin
Publicado 2012

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

por Papadopoulos, Nicholas, Martin, Joel, Ruan, Qin, Rafique, Ashique, Rosconi, Michael P., Shi, Ergang, Pyles, Erica A., Yancopoulos, George D., Stahl, Neil, Wiegand, Stanley J.
Publicado 2012

The Efficacy, Tolerability, and Joint Safety of Fasinumab in Osteoarthritis Pain: A Phase IIb/III Double‐Blind, Placebo‐Controlled, Randomized Clinical Trial

por Dakin, Paula, DiMartino, Stephen J., Gao, Haitao, Maloney, Jennifer, Kivitz, Alan J., Schnitzer, Thomas J., Stahl, Neil, Yancopoulos, George D., Geba, Gregory P.
Publicado 2019

Interleukin-22 promotes fibroblast- mediated wound repair in the skin

por McGee, Heather M., Schmidt, Barbara, Booth, Carmen J., Yancopoulos, George D., Valenzuela, David M., Murphy, Andrew J., Stevens, Sean, Flavell, Richard A., Horsley, Valerie
Publicado 2012

Sarilumab for the treatment of ankylosing spondylitis: results of a Phase II, randomised, double-blind, placebo-controlled study (ALIGN)

por Sieper, Joachim, Braun, Jürgen, Kay, Jonathan, Badalamenti, Salvatore, Radin, Allen R, Jiao, Lixia, Fiore, Stefano, Momtahen, Tanya, Yancopoulos, George D, Stahl, Neil, Inman, Robert D
Publicado 2015

Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the r...

por Huizinga, Tom W J, Fleischmann, Roy M, Jasson, Martine, Radin, Allen R, van Adelsberg, Janet, Fiore, Stefano, Huang, Xiaohong, Yancopoulos, George D, Stahl, Neil, Genovese, Mark C
Publicado 2014

Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor

por Daly, Christopher, Qian, Xiaozhong, Castanaro, Carla, Pasnikowski, Elizabeth, Jiang, Xiabo, Thomson, Benjamin R., Quaggin, Susan E., Papadopoulos, Nicholas, Wei, Yang, Rudge, John S., Thurston, Gavin, Yancopoulos, George D., Davis, Samuel
Publicado 2018

Efficacy and safety of fasinumab in patients with chronic low back pain: a phase II/III randomised clinical trial

por Dakin, Paula, Kivitz, Alan J, Gimbel, Joseph S, Skrepnik, Nebojsa, DiMartino, Stephen J, Emeremni, Chetachi A, Gao, Haitao, Stahl, Neil, Weinreich, David M, Yancopoulos, George D, Geba, Gregory P
Publicado 2021

Compassionate Use of REGEN-COV(®) in Patients With Coronavirus Disease 2019 (COVID-19) and Immunodeficiency-Associated Antibody Disorders

por Stein, David, Oviedo-Orta, Ernesto, Kampman, Wendy A, McGinniss, Jennifer, Betts, George, McDermott, Margaret, Holly, Beth, Lancaster, Johnathan M, Braunstein, Ned, Yancopoulos, George D, Weinreich, David M
Publicado 2021

Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM

por Saotome, Kei, Dudgeon, Drew, Colotti, Kiersten, Moore, Michael J., Jones, Jennifer, Zhou, Yi, Rafique, Ashique, Yancopoulos, George D., Murphy, Andrew J., Lin, John C., Olson, William C., Franklin, Matthew C.
Publicado 2023

Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature

por Takahashi, Keiko, Kim, Rachel, Lauhan, Colette, Park, Yuna, Nguyen, Nghiep G., Vestweber, Dietmar, Dominguez, Melissa G., Valenzuela, David M., Murphy, Andrew J., Yancopoulos, George D., Gale, Nicholas W., Takahashi, Takamune
Publicado 2017

Association of High Serum Interleukin‐6 Levels With Severe Progression of Rheumatoid Arthritis and Increased Treatment Response Differentiating Sarilumab From Adalimumab or Methotr...

por Boyapati, Anita, Schwartzman, Sergio, Msihid, Jérôme, Choy, Ernest, Genovese, Mark C., Burmester, Gerd R., Lam, Gordon, Kimura, Toshio, Sadeh, Jonathan, Weinreich, David M., Yancopoulos, George D., Graham, Neil M. H.
Publicado 2020

Structural insights into the assembly of gp130 family cytokine signaling complexes

por Zhou, Yi, Stevis, Panayiotis E., Cao, Jing, Saotome, Kei, Wu, Jiaxi, Glatman Zaretsky, Arielle, Haxhinasto, Sokol, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Mark W., Olson, William C., Franklin, Matthew C.
Publicado 2023

Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice

por Latres, Esther, Pangilinan, Jeffrey, Miloscio, Lawrence, Bauerlein, Roy, Na, Erqian, Potocky, Terra B., Huang, Ying, Eckersdorff, Mark, Rafique, Ashique, Mastaitis, Jason, Lin, Calvin, Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper, Stitt, Trevor
Publicado 2015

Mice completely lacking immunoproteasomes display major alterations in antigen presentation

por Kincaid, Eleanor Z, Che, Jenny W, York, Ian, Escobar, Hernando, Reyes-Vargas, Eduardo, Delgado, Julio C., Welsh, Raymond M, Karow, Margaret L., Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Rock, Kenneth L
Publicado 2011

Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung

por Nair, Meera G., Du, Yurong, Perrigoue, Jacqueline G., Zaph, Colby, Taylor, Justin J., Goldschmidt, Michael, Swain, Gary P., Yancopoulos, George D., Valenzuela, David M., Murphy, Andrew, Karow, Margaret, Stevens, Sean, Pearce, Edward J., Artis, David
Publicado 2009

Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung

por Nair, Meera G., Du, Yurong, Perrigoue, Jacqueline G., Zaph, Colby, Taylor, Justin J., Goldschmidt, Michael, Swain, Gary P., Yancopoulos, George D., Valenzuela, David M., Murphy, Andrew, Karow, Margaret, Stevens, Sean, Pearce, Edward J., Artis, David
Publicado 2009