TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance

por Yang, Acong, Bofill-De Ros, Xavier, Stanton, Ryan, Shao, Tie-Juan, Villanueva, Patricia, Gu, Shuo
Publicado 2022

AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2

por Yang, Acong, Shao, Tie-Juan, Bofill-De Ros, Xavier, Lian, Chuanjiang, Villanueva, Patricia, Dai, Lisheng, Gu, Shuo
Publicado 2020

Flexible pri-miRNA structures enable tunable production of 5’ isomiRs

por Bofill-De Ros, Xavier, Hong, Zhenyi, Birkenfeld, Ben, Alamo-Ortiz, Sarangelica, Yang, Acong, Dai, Lisheng, Gu, Shuo
Publicado 2022

Cytoplasmic Drosha activity generated by alternative splicing

por Dai, Lisheng, Chen, Kevin, Youngren, Brenda, Kulina, Julia, Yang, Acong, Guo, Zhengyu, Li, Jin, Yu, Peng, Gu, Shuo
Publicado 2016

Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals

por Lee, Seungjae, Jee, David, Srivastava, Sid, Yang, Acong, Ramidi, Abhinav, Shang, Renfu, Bortolamiol-Becet, Diane, Pfeffer, Sébastien, Gu, Shuo, Wen, Jiayu, Lai, Eric C.
Publicado 2023

Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires

por Bofill-De Ros, Xavier, Kasprzak, Wojciech K., Bhandari, Yuba, Fan, Lixin, Cavanaugh, Quinn, Jiang, Minjie, Dai, Lisheng, Yang, Acong, Shao, Tie-Juan, Shapiro, Bruce A., Wang, Yun-Xing, Gu, Shuo
Publicado 2019

SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis

por Parthibane, Velayoudame, Lin, Jing, Acharya, Diwash, Abimannan, Thiruvaimozhi, Srideshikan, Sargur Madabushi, Klarmann, Kimberly, Yang, Acong, Soheilian, Ferri, Nagashima, Kunio, Fox, Stephen D., Andresson, Thorkell, Tessarollo, Lino, Keller, Jonathan R., Acharya, Usha, Acharya, Jairaj K.
Publicado 2021