Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes

por Yang, Chengran, Fagan, Anne M., Perrin, Richard J., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos
Publicado 2022

Quantitative Nucleotide Level Analysis of Regulation of Translation in Response to Depolarization of Cultured Neural Cells

por Dalal, Jasbir S., Yang, Chengran, Sapkota, Darshan, Lake, Allison M., O'Brien, David R., Dougherty, Joseph D.
Publicado 2017

White matter abnormalities in the Hdc knockout mouse, a model of tic and OCD pathophysiology

por Jindachomthong, Kantiya, Yang, Chengran, Huang, Yuegao, Coman, Daniel, Rapanelli, Maximiliano, Hyder, Fahmeed, Dougherty, Joseph, Frick, Luciana, Pittenger, Christopher
Publicado 2022

Implementing quantum dimensionality reduction for non-Markovian stochastic simulation

por Wu, Kang-Da, Yang, Chengran, He, Ren-Dong, Gu, Mile, Xiang, Guo-Yong, Li, Chuan-Feng, Guo, Guang-Can, Elliott, Thomas J.
Publicado 2023

Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain

por Sapkota, Darshan, Lake, Allison M., Yang, Wei, Yang, Chengran, Wesseling, Hendrik, Guise, Amanda, Uncu, Ceren, Dalal, Jasbir S., Kraft, Andrew W., Lee, Jin-Moo, Sands, Mark S., Steen, Judith A., Dougherty, Joseph D.
Publicado 2019

Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials

por Loomis, Stephanie J., Sadhu, Nilanjana, Fisher, Elizabeth, Gafson, Arie R., Huang, Yunfeng, Yang, Chengran, Hughes, Emily E., Marshall, Eric, Herman, Ann, John, Sally, Runz, Heiko, Jia, Xiaoming, Bhangale, Tushar, Bronson, Paola G.
Publicado 2023

A 3’UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP

por Chemparathy, Augustine, Guen, Yann Le, Zeng, Yi, Gorzynski, John, Jensen, Tanner, Yang, Chengran, Kasireddy, Nandita, Talozzi, Lia, Belloy, Michael E., Stewart, Ilaria, Gitler, Aaron D., Wagner, Anthony D., Mormino, Elizabeth, Henderson, Victor W., Wyss-Coray, Tony, Ashley, Euan, Cruchaga, Carlos, Greicius, Michael D.
Publicado 2023

Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellness

por Wang, Ciyang, Western, Dan, Yang, Chengran, Ali, Muhammad, Wang, Lihua, Gorijala, Priyanka, Timsina, Jigyasha, Ruiz, Agustín, Pastor, Pau, Fernandez, Maria, Panyard, Daniel, Engelman, Corinne, Deming, Yuetiva, Boada, Merce, Cano, Amanda, García-González, Pablo, Graff-Radford, Neill, Mori, Hiroshi, Lee, Jae-Hong, Perrin, Richard, Sung, Yun Ju, Cruchaga, Carlos
Publicado 2023

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

por Yang, Chengran, Farias, Fabiana H.G., Ibanez, Laura, Suhy, Adam, Sadler, Brooke, Fernandez, Maria Victoria, Wang, Fengxian, Bradley, Joseph L., Eiffert, Brett, Bahena, Jorge A., Budde, John P., Li, Zeran, Dube, Umber, Sung, Yun Ju, Mihindukulasuriya, Kathie A., Morris, John C., Fagan, Anne M., Perrin, Richard J., Benitez, Bruno A., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos
Publicado 2021

Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson’s disease

por Phillips, Bridget, Western, Daniel, Wang, Lihua, Timsina, Jigyasha, Sun, Yichen, Gorijala, Priyanka, Yang, Chengran, Do, Anh, Nykänen, Niko-Petteri, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Morris, John C., Schindler, Suzanne E., Fagan, Anne M., Puerta, Raquel, García-González, Pablo, de Rojas, Itziar, Marquié, Marta, Boada, Mercè, Ruiz, Agustin, Perlmutter, Joel S., Ibanez, Laura, Perrin, Richard J., Sung, Yun Ju, Cruchaga, Carlos
Publicado 2023

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

por Ibanez, Laura, Bahena, Jorge A., Yang, Chengran, Dube, Umber, Farias, Fabiana H. G., Budde, John P., Bergmann, Kristy, Brenner-Webster, Carol, Morris, John C., Perrin, Richard J., Cairns, Nigel J., O’Donnell, John, Álvarez, Ignacio, Diez-Fairen, Monica, Aguilar, Miquel, Miller, Rebecca, Davis, Albert A., Pastor, Pau, Kotzbauer, Paul, Campbell, Meghan C., Perlmutter, Joel S., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos, Benitez, Bruno A.
Publicado 2020

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer’s disease

por Cruchaga, Carlos, Western, Dan, Timsina, Jigyasha, Wang, Lihua, Wang, Ciyang, Yang, Chengran, Ali, Muhammad, Beric, Aleksandra, Gorijala, Priyanka, Kohlfeld, Patsy, Budde, John, Levey, Allan, Morris, John, Perrin, Richard, Ruiz, Agustín, Marquié, Marta, Boada, Mercè, de Rojas, Itziar, Rutledge, Jarod, Oh, Hamilton, Wilson, Edward, Guen, Yann Le, Alvarez, Ignacio, Aguilar, Miquel, Greicius, Michael, Pastor, Pau, Pulford, David, Ibanez, Laura, Wyss-Coray, Tony, Sung, Yun Ju, Phillips, Bridget
Publicado 2023