Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain

por Klein, Hans-Ulrich, Trumpff, Caroline, Yang, Hyun-Sik, Lee, Annie J., Picard, Martin, Bennett, David A., De Jager, Philip L.
Publicado 2021

UNC5C variants are associated with cerebral amyloid angiopathy

por Yang, Hyun-Sik, White, Charles C., Chibnik, Lori B., Klein, Hans-Ulrich, Schneider, Julie A., Bennett, David A., De Jager, Philip L.
Publicado 2017

Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals

por Chhatwal, Jasmeer P., Schultz, Aaron P., Dang, Yifan, Ostaszewski, Beth, Liu, Lei, Yang, Hyun-Sik, Johnson, Keith A., Sperling, Reisa A., Selkoe, Dennis J.
Publicado 2020

Using community-based geographical information system (GIS) to recruit older Asian Americans in an Alzheimer’s disease study

por Lee, Haeok, Ha, Hoehun, Yim, Sejung, Yang, Hyun-Sik, Lee, Veronica, Hong, Eunju, Chow, Tiffany W, Park, Van Ta, Wang, Li-San, Jun, Gyungah, Choi, Yun-Beom
Publicado 2023

Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau

por Van Egroo, Maxime, Riphagen, Joost M., Ashton, Nicholas J., Janelidze, Shorena, Sperling, Reisa A., Johnson, Keith A., Yang, Hyun-Sik, Bennett, David A., Blennow, Kaj, Hansson, Oskar, Zetterberg, Henrik, Jacobs, Heidi I. L.
Publicado 2023

Longitudinal degradation of the default/salience network axis in symptomatic individuals with elevated amyloid burden.

por Schultz, Aaron P, Buckley, Rachel F, Hampton, Olivia L, Scott, Matthew R, Properzi, Michael J, Peña-Gómez, Cleofé, Pruzin, Jeremy J, Yang, Hyun-Sik, Johnson, Keith A, Sperling, Reisa A, Chhatwal, Jasmeer P
Publicado 2019

Brain microRNAs are associated with variation in cognitive trajectory in advanced age

por Wingo, Aliza P., Wang, Mengli, Liu, Jiaqi, Breen, Michael S., Yang, Hyun-Sik, Tang, Beisha, Schneider, Julie A., Seyfried, Nicholas T., Lah, James J., Levey, Allan I., Bennett, David A., Jin, Peng, De Jager, Philip L., Wingo, Thomas S.
Publicado 2022

Physical activity is associated with increased resting‐state functional connectivity in networks predictive of cognitive decline in clinically unimpaired older adults

por Pruzin, Jeremy J., Klein, Hannah, Rabin, Jennifer S., Schultz, Aaron P., Kirn, Dylan R., Yang, Hyun‐Sik, Buckley, Rachel F., Scott, Mathew R., Properzi, Michael, Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A., Chhatwal, Jasmeer P.
Publicado 2022

Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults

por Gatchel, Jennifer R., Rabin, Jennifer S., Buckley, Rachel F., Locascio, Joseph J., Quiroz, Yakeel T., Yang, Hyun-Sik, Vannini, Patrizia, Amariglio, Rebecca E., Rentz, Dorene M., Properzi, Michael, Donovan, Nancy J., Blacker, Deborah, Johnson, Keith A., Sperling, Reisa A., Marshall, Gad A.
Publicado 2019

Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data

por White, Charles C., Yang, Hyun-Sik, Yu, Lei, Chibnik, Lori B., Dawe, Robert J., Yang, Jingyun, Klein, Hans-Ulrich, Felsky, Daniel, Ramos-Miguel, Alfredo, Arfanakis, Konstantinos, Honer, William G., Sperling, Reisa A., Schneider, Julie A., Bennett, David A., De Jager, Philip L.
Publicado 2017

Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease

por Yang, Hyun-Sik, Teng, Ling, Kang, Daniel, Menon, Vilas, Ge, Tian, Finucane, Hilary K., Schultz, Aaron P., Properzi, Michael, Klein, Hans-Ulrich, Chibnik, Lori B., Schneider, Julie A., Bennett, David A., Hohman, Timothy J., Mayeux, Richard P., Johnson, Keith A., De Jager, Philip L., Sperling, Reisa A.
Publicado 2023

Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease

por Yang, Hyun-Sik, Teng, Ling, Kang, Daniel, Menon, Vilas, Ge, Tian, Finucane, Hilary K., Schultz, Aaron P., Properzi, Michael, Klein, Hans-Ulrich, Chibnik, Lori B., Schneider, Julie A., Bennett, David A., Hohman, Timothy J., Mayeux, Richard P., Johnson, Keith A., De Jager, Philip L., Sperling, Reisa A.
Publicado 2023

Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer’s disease

por Langella, Stephanie, Barksdale, N. Gil, Vasquez, Daniel, Aguillon, David, Chen, Yinghua, Su, Yi, Acosta-Baena, Natalia, Acosta-Uribe, Juliana, Baena, Ana Y., Garcia-Ospina, Gloria, Giraldo-Chica, Margarita, Tirado, Victoria, Muñoz, Claudia, Ríos-Romenets, Silvia, Guzman-Martínez, Claudia, Oliveira, Gabriel, Yang, Hyun-Sik, Vila-Castelar, Clara, Pruzin, Jeremy J., Ghisays, Valentina, Arboleda-Velasquez, Joseph F., Kosik, Kenneth S., Reiman, Eric M., Lopera, Francisco, Quiroz, Yakeel T.
Publicado 2023

Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer’s Dementia

por Ouellette, Andrew R., Neuner, Sarah M., Dumitrescu, Logan, Anderson, Laura C., Gatti, Daniel M., Mahoney, Emily R., Bubier, Jason A., Churchill, Gary, Peters, Luanne, Huentelman, Matthew J., Herskowitz, Jeremy H., Yang, Hyun-Sik, Smith, Alexandra N., Reitz, Christiane, Kunkle, Brian W., White, Charles C., De Jager, Philip L., Schneider, Julie A., Bennett, David A., Seyfried, Nicholas T., Chesler, Elissa J., Hadad, Niran, Hohman, Timothy J., Kaczorowski, Catherine C.
Publicado 2020

Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

por Dumitrescu, Logan, Mahoney, Emily R, Mukherjee, Shubhabrata, Lee, Michael L, Bush, William S, Engelman, Corinne D, Lu, Qiongshi, Fardo, David W, Trittschuh, Emily H, Mez, Jesse, Kaczorowski, Catherine, Hernandez Saucedo, Hector, Widaman, Keith F, Buckley, Rachel, Properzi, Michael, Mormino, Elizabeth, Yang, Hyun-Sik, Harrison, Tessa, Hedden, Trey, Nho, Kwangsik, Andrews, Shea J, Tommet, Doug, Hadad, Niran, Sanders, R Elizabeth, Ruderfer, Douglas M, Gifford, Katherine A, Moore, Annah M, Cambronero, Francis, Zhong, Xiaoyuan, Raghavan, Neha S, Vardarajan, Badri, Pericak-Vance, Margaret A, Farrer, Lindsay A, Wang, Li-San, Cruchaga, Carlos, Schellenberg, Gerard, Cox, Nancy J, Haines, Jonathan L, Keene, C Dirk, Saykin, Andrew J, Larson, Eric B, Sperling, Reisa A, Mayeux, Richard, Bennett, David A, Schneider, Julie A, Crane, Paul K, Jefferson, Angela L, Hohman, Timothy J
Publicado 2020

Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease

por Ali, Muhammad, Archer, Derek B., Gorijala, Priyanka, Western, Daniel, Timsina, Jigyasha, Fernández, Maria V., Wang, Ting-Chen, Satizabal, Claudia L., Yang, Qiong, Beiser, Alexa S., Wang, Ruiqi, Chen, Gengsheng, Gordon, Brian, Benzinger, Tammie L. S., Xiong, Chengjie, Morris, John C., Bateman, Randall J., Karch, Celeste M., McDade, Eric, Goate, Alison, Seshadri, Sudha, Mayeux, Richard P., Sperling, Reisa A., Buckley, Rachel F., Johnson, Keith A., Won, Hong-Hee, Jung, Sang-Hyuk, Kim, Hang-Rai, Seo, Sang Won, Kim, Hee Jin, Mormino, Elizabeth, Laws, Simon M., Fan, Kang-Hsien, Kamboh, M. Ilyas, Vemuri, Prashanthi, Ramanan, Vijay K., Yang, Hyun-Sik, Wenzel, Allen, Rajula, Hema Sekhar Reddy, Mishra, Aniket, Dufouil, Carole, Debette, Stephanie, Lopez, Oscar L., DeKosky, Steven T., Tao, Feifei, Nagle, Michael W., Hohman, Timothy J., Sung, Yun Ju, Dumitrescu, Logan, Cruchaga, Carlos
Publicado 2023

LATE-NC staging in routine neuropathologic diagnosis: an update

por Nelson, Peter T., Lee, Edward B., Cykowski, Matthew D., Alafuzoff, Irina, Arfanakis, Konstantinos, Attems, Johannes, Brayne, Carol, Corrada, Maria M., Dugger, Brittany N., Flanagan, Margaret E., Ghetti, Bernardino, Grinberg, Lea T., Grossman, Murray, Grothe, Michel J., Halliday, Glenda M., Hasegawa, Masato, Hokkanen, Suvi R. K., Hunter, Sally, Jellinger, Kurt, Kawas, Claudia H., Keene, C. Dirk, Kouri, Naomi, Kovacs, Gabor G., Leverenz, James B., Latimer, Caitlin S., Mackenzie, Ian R., Mao, Qinwen, McAleese, Kirsty E., Merrick, Richard, Montine, Thomas J., Murray, Melissa E., Myllykangas, Liisa, Nag, Sukriti, Neltner, Janna H., Newell, Kathy L., Rissman, Robert A., Saito, Yuko, Sajjadi, S. Ahmad, Schwetye, Katherine E., Teich, Andrew F., Thal, Dietmar R., Tomé, Sandra O., Troncoso, Juan C., Wang, Shih-Hsiu J., White, Charles L., Wisniewski, Thomas, Yang, Hyun-Sik, Schneider, Julie A., Dickson, Dennis W., Neumann, Manuela
Publicado 2022

Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease

por Eissman, Jaclyn M, Dumitrescu, Logan, Mahoney, Emily R, Smith, Alexandra N, Mukherjee, Shubhabrata, Lee, Michael L, Scollard, Phoebe, Choi, Seo Eun, Bush, William S, Engelman, Corinne D, Lu, Qiongshi, Fardo, David W, Trittschuh, Emily H, Mez, Jesse, Kaczorowski, Catherine C, Hernandez Saucedo, Hector, Widaman, Keith F, Buckley, Rachel F, Properzi, Michael J, Mormino, Elizabeth C, Yang, Hyun Sik, Harrison, Theresa M, Hedden, Trey, Nho, Kwangsik, Andrews, Shea J, Tommet, Douglas, Hadad, Niran, Sanders, R Elizabeth, Ruderfer, Douglas M, Gifford, Katherine A, Zhong, Xiaoyuan, Raghavan, Neha S, Vardarajan, Badri N, Pericak-Vance, Margaret A, Farrer, Lindsay A, Wang, Li San, Cruchaga, Carlos, Schellenberg, Gerard D, Cox, Nancy J, Haines, Jonathan L, Keene, C Dirk, Saykin, Andrew J, Larson, Eric B, Sperling, Reisa A, Mayeux, Richard, Cuccaro, Michael L, Bennett, David A, Schneider, Julie A, Crane, Paul K, Jefferson, Angela L, Hohman, Timothy J
Publicado 2022