Frontotemporal dementia‐linked P112H mutation of TDP‐43 induces protein structural change and impairs its RNA binding function

por Agrawal, Sashank, Jain, Monika, Yang, Wei‐Zen, Yuan, Hanna S.
Publicado 2020

Tudor staphylococcal nuclease is a structure-specific ribonuclease that degrades RNA at unstructured regions during microRNA decay

por Li, Chia-Lung, Yang, Wei-Zen, Shi, Zhonghao, Yuan, Hanna S.
Publicado 2018

Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing

por Li, Chia-Lung, Yang, Wei-Zen, Chen, Yi-Ping, Yuan, Hanna S.
Publicado 2008

Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer

por Lin, Jason L. J., Wu, Chyuan-Chuan, Yang, Wei-Zen, Yuan, Hanna S.
Publicado 2016

Structural insights into nanoRNA degradation by human Rexo2

por Chu, Lee-Ya, Agrawal, Sashank, Chen, Yi-Ping, Yang, Wei-Zen, Yuan, Hanna S.
Publicado 2019

Efficient Strategy to Design Protease Inhibitors: Application to Enterovirus 71 2A Protease

por Chen, Ting, Grauffel, Cédric, Yang, Wei-Zen, Chen, Yi-Ping, Yuan, Hanna S., Lim, Carmay
Publicado 2022

Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation

por Lin, Chia Liang, Wang, Yi-Ting, Yang, Wei-Zen, Hsiao, Yu-Yuan, Yuan, Hanna S.
Publicado 2012

Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B

por Lin, Chien-Chu, Chen, Yi-Ping, Yang, Wei-Zen, Shen, James C K, Yuan, Hanna S
Publicado 2020

Crystal structure of dimeric human PNPase reveals why disease-linked mutants suffer from low RNA import and degradation activities

por Golzarroshan, Bagher, Lin, Chia-Liang, Li, Chia-Lung, Yang, Wei-Zen, Chu, Lee-Ya, Agrawal, Sashank, Yuan, Hanna S
Publicado 2018

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

por Sargsyan, Karen, Lin, Chien-Chu, Chen, Ting, Grauffel, Cédric, Chen, Yi-Ping, Yang, Wei-Zen, Yuan, Hanna S., Lim, Carmay
Publicado 2020

Mechanistic Insights into Harmine-Mediated Inhibition of Human DNA Methyltransferases and Prostate Cancer Cell Growth

por Cho, Chao-Cheng, Lin, Chun-Jung, Huang, Hsun-Ho, Yang, Wei-Zen, Fei, Cheng-Yin, Lin, Hsin-Ying, Lee, Ming-Shyue, Yuan, Hanna S.
Publicado 2023

Correction: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

por Sargsyan, Karen, Lin, Chien-Chu, Chen, Ting, Grauffel, Cédric, Chen, Yi-Ping, Yang, Wei-Zen, Liang, Jian-Jong, Liao, Chun-Che, Lin, Yi-Ling, Yuan, Hanna S., Lim, Carmay
Publicado 2021