TNF-α and IL-1β increase Ca(2+) leak from the sarcoplasmic reticulum and susceptibility to arrhythmia in rat ventricular myocytes

por Duncan, David J., Yang, Zhaokang, Hopkins, Philip M., Steele, Derek S., Harrison, Simon M.
Publicado 2010

Flecainide induces a sustained countercurrent dependent effect on RyR2 in permeabilized WT ventricular myocytes but not in intact cells

por Steer, Emma J., Yang, Zhaokang, Al-Owais, Moza M., Kirton, Hannah M., White, Edward, Steele, Derek S.
Publicado 2023

Epac2-Rap1 Signaling Regulates Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias

por Yang, Zhaokang, Kirton, Hannah M., Al-Owais, Moza, Thireau, Jérôme, Richard, Sylvain, Peers, Chris, Steele, Derek S.
Publicado 2017

A Mechanism for Statin-Induced Susceptibility to Myopathy

por Lotteau, Sabine, Ivarsson, Niklas, Yang, Zhaokang, Restagno, Damien, Colyer, John, Hopkins, Philip, Weightman, Andrew, Himori, Koichi, Yamada, Takashi, Bruton, Joseph, Steele, Derek, Westerblad, Håkan, Calaghan, Sarah
Publicado 2019

Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform

por Venturi, Elisa, Lindsay, Chris, Lotteau, Sabine, Yang, Zhaokang, Steer, Emma, Witschas, Katja, Wilson, Abigail D, Wickens, James R, Russell, Angela J, Steele, Derek, Calaghan, Sarah, Sitsapesan, Rebecca
Publicado 2018

Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy

por Sheard, Thomas M. D., Hurley, Miriam E., Colyer, John, White, Ed, Norman, Ruth, Pervolaraki, Eleftheria, Narayanasamy, Kaarjel K., Hou, Yufeng, Kirton, Hannah M., Yang, Zhaokang, Hunter, Liam, Shim, Jung-uk, Clowsley, Alexander H., Smith, Andrew J., Baddeley, David, Soeller, Christian, Colman, Michael A., Jayasinghe, Izzy
Publicado 2019