The discovery of a novel compound with potent antitumor activity: virtual screening, synthesis, biological evaluation and preliminary mechanism study

por Jin, Yuanyuan, Li, Linhu, Yang, Zhaoyong, Liu, Mingliang, Guo, Huiyuan, Shen, Weiyi
Publicado 2017

Directed evolution of a cyclodipeptide synthase with new activities via label-free mass spectrometric screening

por Zhang, Songya, Zhu, Jing, Fan, Shuai, Xie, Wenhao, Yang, Zhaoyong, Si, Tong
Publicado 2022

Biosynthetic and Synthetic Strategies for Assembling Capuramycin-Type Antituberculosis Antibiotics

por Biecker, Ashley L., Liu, Xiaodong, Thorson, Jon S., Yang, Zhaoyong, Van Lanen, Steven G.
Publicado 2019

DFT calculation and NMR data of novel aryloxymaleimides and the intermediates and transition states in the reaction

por Yan, Maocai, Zhang, Zhen, Zhou, Jinhui, Li, Wei, Zhang, Chunyan, Fan, Shuai, Yang, Zhaoyong
Publicado 2019

Catalytic Hydrolysis Mechanism of Cocaine by Human Carboxylesterase 1: An Orthoester Intermediate Slows Down the Reaction

por Yan, Maocai, Zhang, Zhen, Liu, Zhaoming, Zhang, Chunyan, Zhang, Jingchang, Fan, Shuai, Yang, Zhaoyong
Publicado 2019

Structural insights into the specific interaction between Geobacillus stearothermophilus tryptophanyl-tRNA synthetase and antimicrobial Chuangxinmycin

por Fan, Shuai, Lv, Guangxin, Feng, Xiao, Wu, Guangteng, Jin, Yuanyuan, Yan, Maocai, Yang, Zhaoyong
Publicado 2022

The antitumor activity of hPRDX5 against pancreatic cancer and the possible mechanisms

por Cui, Lihua, Jin, Yuanyuan, Zou, Sen, Xun, Jing, Yu, Xiangyang, Zhang, Qi, Yang, Zhaoyong
Publicado 2022

The identification of goat peroxiredoxin-5 and the evaluation and enhancement of its stability by nanoparticle formation

por Feng, Xiaozhou, Liu, Juanjuan, Fan, Shuai, Liu, Fan, Li, Yadong, Jin, Yuanyuan, Bai, Liping, Yang, Zhaoyong
Publicado 2016

The antitumor activity and preliminary modeling on the potential mechanism of action of human peroxiredoxin-5

por Liu, Juanjuan, Feng, Xiaozhou, Jin, Yuanyuan, Sun, Zhengyang, Meng, Haoyi, Zhang, Zhifei, Hu, Laixing, Yang, Zhaoyong
Publicado 2017

Enhanced Rishirilide Biosynthesis by a Rare In-Cluster Phosphopantetheinyl Transferase in Streptomyces xanthophaeus

por Zhang, Songya, Fan, Shuai, Zhu, Jing, Zhou, Liying, Yan, Xiaohui, Yang, Zhaoyong, Si, Tong, Liu, Tao
Publicado 2022

Insights into the Phosphoryl Transfer Mechanism of Human Ubiquitous Mitochondrial Creatine Kinase

por Li, Quanjie, Fan, Shuai, Li, Xiaoyu, Jin, Yuanyuan, He, Weiqing, Zhou, Jinming, Cen, Shan, Yang, ZhaoYong
Publicado 2016

The Complex Structure of Protein AaLpxC from Aquifex aeolicus with ACHN-975 Molecule Suggests an Inhibitory Mechanism at Atomic-Level against Gram-Negative Bacteria

por Fan, Shuai, Li, Danyang, Yan, Maocai, Feng, Xiao, Lv, Guangxin, Wu, Guangteng, Jin, Yuanyuan, Wang, Yucheng, Yang, Zhaoyong
Publicado 2021

Identification of potential inhibitors of omicron variant of SARS-Cov-2 RBD based virtual screening, MD simulation, and DFT

por Lü, Xudong, Feng, Cuiyue, Lü, Ruijie, Wei, Xiyu, Fan, Shuai, Yan, Maocai, Zhu, Xiandui, Zhang, Zhifei, Yang, Zhaoyong
Publicado 2022