Overcoming high level adenosine-mediated immunosuppression by DZD2269, a potent and selective A2aR antagonist

por Bai, Yu, Zhang, Xin, Zheng, Jie, Liu, Ziyi, Yang, Zhenfan, Zhang, Xiaolin
Publicado 2022

Pharmacokinetic characteristics of golidocitinib, a highly selective JAK1 inhibitor, in healthy adult participants

por Chen, Kan, Guan, Xiaoduo, Yang, Zhenfan, Zhou, Yue, Liu, Ziyi, Deng, Xueyuan, Liu, Donghong, Hu, Pei, Chen, Rui
Publicado 2023

Osimertinib (AZD9291) increases radio-sensitivity in EGFR T790M non-small cell lung cancer

por Wang, Nannan, Wang, Linlin, Meng, Xiangjiao, Wang, Jia, Zhu, Lifang, Liu, Changting, Li, Shaorong, Zheng, Li, Yang, Zhenfan, Xing, Ligang, Yu, Jinming
Publicado 2019

EGFR G796D mutation mediates resistance to osimertinib

por Zheng, Di, Hu, Min, Bai, Yu, Zhu, Xuehua, Lu, Xuesong, Wu, Chunyan, Wang, Jiying, Liu, Li, Wang, Zheng, Ni, Jian, Yang, Zhenfan, Xu, Jianfang
Publicado 2017

Heterogeneous responses and resistant mechanisms to crizotinib in ALK‐positive advanced non‐small cell lung cancer

por Kang, Jin, Chen, Hua‐Jun, Zhang, Xu‐Chao, Su, Jian, Zhou, Qing, Tu, Hai‐Yan, Wang, Zhen, Wang, Bin‐Chao, Zhong, Wen‐Zhao, Yang, Xue‐Ning, Chen, Zhi‐Hong, Ding, Yan, Wu, Xue, Wang, Mei, Fu, Jian‐Gang, Yang, Zhenfan, Zhang, Xian, Shao, Yang W., Wu, Yi‐Long, Yang, Jin‐Ji
Publicado 2018

The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models

por Durant, Stephen T., Zheng, Li, Wang, Yingchun, Chen, Kan, Zhang, Lingli, Zhang, Tianwei, Yang, Zhenfan, Riches, Lucy, Trinidad, Antonio G., Fok, Jacqueline H. L., Hunt, Tom, Pike, Kurt G., Wilson, Joanne, Smith, Aaron, Colclough, Nicola, Reddy, Venkatesh Pilla, Sykes, Andrew, Janefeldt, Annika, Johnström, Peter, Varnäs, Katarina, Takano, Akihiro, Ling, Stephanie, Orme, Jonathan, Stott, Jonathan, Roberts, Caroline, Barrett, Ian, Jones, Gemma, Roudier, Martine, Pierce, Andrew, Allen, Jasmine, Kahn, Jenna, Sule, Amrita, Karlin, Jeremy, Cronin, Anna, Chapman, Melissa, Valerie, Kristoffer, Illingworth, Ruth, Pass, Martin
Publicado 2018