Site-directed transposon integration in human cells

por Yant, Stephen R., Huang, Yong, Akache, Bassel, Kay, Mark A.
Publicado 2007

1448. Forgiveness of BIC/FTC/TAF: In Vitro Simulations of Intermittent Poor Adherence Find Limited HIV-1 Breakthrough and High Barrier to Resistance

por Mulato, Andrew, Acosta, Rima K, Yant, Stephen R, Cihlar, Tomas, White, Kirsten L
Publicado 2020

888. In Vitro Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence

por Acosta, Rima K, Mulato, Andrew, D’Antoni, Michelle L, Yant, Stephen R, Cihlar, Tomas, White, Kirsten L
Publicado 2021

Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence In Vitro

por Acosta, Rima K., D’Antoni, Michelle L., Mulato, Andrew, Yant, Stephen R., Cihlar, Tomas, White, Kirsten L.
Publicado 2022

Long-acting lenacapavir acts as an effective preexposure prophylaxis in a rectal SHIV challenge macaque model

por Bekerman, Elena, Yant, Stephen R., VanderVeen, Laurie, Hansen, Derek, Lu, Bing, Rowe, William, Wang, Kelly, Callebaut, Christian
Publicado 2023

A Two-hybrid Screen Identifies Cathepsins B and L as Uncoating Factors for Adeno-associated Virus 2 and 8

por Akache, Bassel, Grimm, Dirk, Shen, Xuan, Fuess, Sally, Yant, Stephen R, Glazer, Dariya S, Park, Julie, Kay, Mark A
Publicado 2007

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

por Peng, Ke, Muranyi, Walter, Glass, Bärbel, Laketa, Vibor, Yant, Stephen R, Tsai, Luong, Cihlar, Tomas, Müller, Barbara, Kräusslich, Hans-Georg
Publicado 2014

TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells

por Bam, Rujuta A., Hansen, Derek, Irrinki, Alivelu, Mulato, Andrew, Jones, Gregg S., Hesselgesser, Joseph, Frey, Christian R., Cihlar, Tomas, Yant, Stephen R.
Publicado 2016

Non-Catalytic Site HIV-1 Integrase Inhibitors Disrupt Core Maturation and Induce a Reverse Transcription Block in Target Cells

por Balakrishnan, Mini, Yant, Stephen R., Tsai, Luong, O’Sullivan, Christopher, Bam, Rujuta A., Tsai, Angela, Niedziela-Majka, Anita, Stray, Kirsten M., Sakowicz, Roman, Cihlar, Tomas
Publicado 2013

539. GS-CA2: A Novel, Potent, and Selective First-In-class Inhibitor of HIV-1 Capsid Function Displays Nonclinical Pharmacokinetics Supporting Long-Acting Potential in Humans

por Zheng, Jim, Yant, Stephen R, Ahmadyar, Shekeba, Chan, Tiffany Y, Chiu, Anna, Cihlar, Tomas, Link, John O, Lu, Bing, Mwangi, Judy, Rowe, William, Schroeder, Scott D, Stepan, George J, Wang, Kelly Wei, Subramanian, Raju, Tse, Winston C
Publicado 2018

Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

por Tsiang, Manuel, Jones, Gregg S., Goldsmith, Joshua, Mulato, Andrew, Hansen, Derek, Kan, Elaine, Tsai, Luong, Bam, Rujuta A., Stepan, George, Stray, Kirsten M., Niedziela-Majka, Anita, Yant, Stephen R., Yu, Helen, Kukolj, George, Cihlar, Tomas, Lazerwith, Scott E., White, Kirsten L., Jin, Haolun
Publicado 2016

Long-acting lenacapavir protects macaques against intravenous challenge with simian-tropic HIV

por Swanstrom, Adrienne E., Gorelick, Robert J., Welker, Jorden L., Schmidt, Fabian, Lu, Bing, Wang, Kelly, Rowe, William, Breed, Matthew W., Killoran, Kristin E., Kramer, Joshua A., Donohue, Duncan, Roser, James D., Bieniasz, Paul D., Hatziioannou, Theodora, Pyle, Cathi, Thomas, James A., Trubey, Charles M., Zheng, Jim, Blair, Wade, Yant, Stephen R., Lifson, Jeffrey D., Del Prete, Gregory Q.
Publicado 2023

Long-acting capsid inhibitor protects macaques from repeat SHIV challenges

por Vidal, Samuel J., Bekerman, Elena, Hansen, Derek, Lu, Bing, Wang, Kelly, Mwangi, Judy, Rowe, William, Campigotto, Federico, Zheng, Jim, Kato, Darryl, Chandrashekar, Abishek, Barrett, Julia, Patel, Shivani, Wan, Huahua, Anioke, Tochi, Mercado, Noe B., Nkolola, Joseph P., Ferguson, Melissa J., Rinaldi, William J., Callebaut, Christian, Blair, Wade, Cihlar, Tomas, Geleziunas, Romas, Yant, Stephen R., Barouch, Dan H.
Publicado 2021