Recent advances in therapeutic CRISPR-Cas9 genome editing: mechanisms and applications

por Zhou, Lifang, Yao, Shaohua
Publicado 2023

Enhancing prime editing via inhibition of mismatch repair pathway

por Jiang, Lurong, Yao, Shaohua
Publicado 2022

Case report: A case of delayed cutaneous metastases from signet-ring cell mixed-type gastric cancer

por Yao, Shaohua, Zhou, Peng, Li, Yiqing, Li, Qin
Publicado 2023

A PCR Based Protocol for Detecting Indel Mutations Induced by TALENs and CRISPR/Cas9 in Zebrafish

por Yu, Chuan, Zhang, Yaguang, Yao, Shaohua, Wei, Yuquan
Publicado 2014

BE-PIGS: a base-editing tool with deaminases inlaid into Cas9 PI domain significantly expanded the editing scope

por Wang, Yanhong, Zhou, Lifang, Liu, Nan, Yao, Shaohua
Publicado 2019

Wolf–Hirschhorn Syndrome Candidate 1 (whsc1) Functions as a Tumor Suppressor by Governing Cell Differentiation

por Yu, Chuan, Yao, Xiaomin, Zhao, Linjie, Wang, Ping, Zhang, Qian, Zhao, Chengjian, Yao, Shaohua, Wei, Yuquan
Publicado 2017

Random-PE: an efficient integration of random sequences into mammalian genome by prime editing

por Jiao, Yaoge, Zhou, Lifang, Tao, Rui, Wang, Yanhong, Hu, Yun, Jiang, Lurong, Li, Li, Yao, Shaohua
Publicado 2021

Identify a Blood-Brain Barrier Penetrating Drug-TNB using Zebrafish Orthotopic Glioblastoma Xenograft Model

por Zeng, Anqi, Ye, Tinghong, Cao, Dan, Huang, Xi, Yang, Yu, Chen, Xiuli, Xie, Yongmei, Yao, Shaohua, Zhao, Chengjian
Publicado 2017

Long-Term Metabolic Correction of Phenylketonuria by AAV-Delivered Phenylalanine Amino Lyase

por Tao, Rui, Xiao, Lin, Zhou, Lifang, Zheng, Zhaoyue, Long, Jie, Zhou, Lixing, Tang, Minghai, Dong, Biao, Yao, Shaohua
Publicado 2020

Long-Term Metabolic Correction of Phenylketonuria by AAV-Delivered Phenylalanine Amino Lyase

por Tao, Rui, Xiao, Lin, Zhou, Lifang, Zheng, Zhaoyue, Long, Jie, Zhou, Lixing, Tang, Minghai, Dong, Biao, Yao, Shaohua
Publicado 2022

HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing

por Liu, Nan, Zhou, Lifang, Lin, Guifeng, Hu, Yun, Jiao, Yaoge, Wang, Yanhong, Liu, Jingming, Yang, Shengyong, Yao, Shaohua
Publicado 2022

HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing

por Liu, Nan, Zhou, Lifang, Lin, Guifeng, Hu, Yun, Jiao, Yaoge, Wang, Yanhong, Liu, Jingming, Yang, Shengyong, Yao, Shaohua
Publicado 2022

DnaQ mediates directional spacer acquisition in the CRISPR-Cas system by a time-dependent mechanism

por Tang, Dongmei, Jia, Tingting, Luo, Yongbo, Mou, Biqin, Cheng, Jie, Qi, Shiqian, Yao, Shaohua, Su, Zhaoming, Yu, Yamei, Chen, Qiang
Publicado 2023

sgBE: a structure-guided design of sgRNA architecture specifies base editing window and enables simultaneous conversion of cytosine and adenosine

por Wang, Yanhong, Zhou, Lifang, Tao, Rui, Liu, Nan, Long, Jie, Qin, Fengming, Tang, Wenling, Yang, Yang, Chen, Qiang, Yao, Shaohua
Publicado 2020

Bi-PE: bi-directional priming improves CRISPR/Cas9 prime editing in mammalian cells

por Tao, Rui, Wang, Yanhong, Jiao, Yaoge, Hu, Yun, Li, Li, Jiang, Lurong, Zhou, Lifang, Qu, Junyan, Chen, Qiang, Yao, Shaohua
Publicado 2022

Internally inlaid SaCas9 base editors enable window specific base editing

por Jiang, Lurong, Long, Jie, Yang, Yang, Zhou, Lifang, Su, Jing, Qin, Fengming, Tang, Wenling, Tao, Rui, Chen, Qiang, Yao, Shaohua
Publicado 2022

Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis

por Wu, Chengyong, Tang, Dongmei, Cheng, Jie, Hu, Daojun, Yang, Zejing, Ma, Xue, He, Haihuai, Yao, Shaohua, Fu, Tian-Min, Yu, Yamei, Chen, Qiang
Publicado 2021

Transdifferentiation of Fast Skeletal Muscle Into Functional Endothelium in Vivo by Transcription Factor Etv2

por Veldman, Matthew B., Zhao, Chengjian, Gomez, Gustavo A., Lindgren, Anne G., Huang, Haigen, Yang, Hanshuo, Yao, Shaohua, Martin, Benjamin L., Kimelman, David, Lin, Shuo
Publicado 2013

Pigment epithelial-derived factor gene loaded novel COOH-PEG-PLGA-COOH nanoparticles promoted tumor suppression by systemic administration

por Yu, Ting, Xu, Bei, He, Lili, Xia, Shan, Chen, Yan, Zeng, Jun, Liu, Yongmei, Li, Shuangzhi, Tan, Xiaoyue, Ren, Ke, Yao, Shaohua, Song, Xiangrong
Publicado 2016

eIF3i activity is critical for endothelial cells in tumor induced angiogenesis through regulating VEGFR and ERK translation

por Zhang, Yaguang, Wang, Ping, Zhang, Qian, Yao, Xiaomin, Zhao, Linjie, Liu, Yibin, Liu, Xiaowei, Tao, Rui, Yu, Chuan, Li, Yuhao, Song, Xiangrong, Yao, Shaohua
Publicado 2017