Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicana In Vitro

por Riezk, Alaa, Raynes, John G., Yardley, Vanessa, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2020

Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis

por Riezk, Alaa, Van Bocxlaer, Katrien, Yardley, Vanessa, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2020

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Yardley, Vanessa, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2017

Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Yardley, Vanessa, Harris, Andy, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2018

Antileishmanial Activity and Synergistic Effects of Amphotericin B Deoxycholate with Allicin and Andrographolide against Leishmania martiniquensis In Vitro

por Intakhan, Nuchpicha, Chanmol, Wetpisit, Somboon, Pradya, Bates, Michelle D., Yardley, Vanessa, Bates, Paul A., Jariyapan, Narissara
Publicado 2020

Novel 2D and 3D Assays to Determine the Activity of Anti-Leishmanial Drugs

por O’Keeffe, Alec, Hale, Christine, Cotton, James A., Yardley, Vanessa, Gupta, Kapish, Ananthanarayanan, Abhishek, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2020

Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Fortes Francisco, Amanda, Yardley, Vanessa, Harris, Andy, Alavijeh, Mo, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2018

Pharmacokinetics and Pharmacodynamics of the Nitroimidazole DNDI-0690 in Mouse Models of Cutaneous Leishmaniasis

por Wijnant, Gert-Jan, Croft, Simon L., de la Flor, Raul, Alavijeh, Mo, Yardley, Vanessa, Braillard, Stéphanie, Mowbray, Charles, Van Bocxlaer, Katrien
Publicado 2019

Protein energy malnutrition increases arginase activity in monocytes and macrophages

por Corware, Karina, Yardley, Vanessa, Mack, Christopher, Schuster, Steffen, Al-Hassi, Hafid, Herath, Shanthi, Bergin, Philip, Modolell, Manuel, Munder, Markus, Müller, Ingrid, Kropf, Pascale
Publicado 2014

Efficacy of oleylphosphocholine in experimental cutaneous leishmaniasis

por Van Bocxlaer, Katrien, Dixon, Jodie, Platteeuw, Johannes J, Van Den Heuvel, Dennie, Mcarthur, Kerri-Nicola, Harris, Andy, Alavijeh, Mo, Croft, Simon L, Yardley, Vanessa
Publicado 2023

Cutaneous Leishmaniasis in Khyber Pakhtunkhwa Province of Pakistan: Clinical Diversity and Species-Level Diagnosis

por Khan, Nazma Habib, Bari, Arfan ul, Hashim, Rizwan, Khan, Inamullah, Muneer, Akhtar, Shah, Akram, Wahid, Sobia, Yardley, Vanessa, O'Neil, Brighid, Sutherland, Colin J.
Publicado 2016

Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome(®) and AmBisome(®) in murine cutaneous leishmaniasis

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Yardley, Vanessa, Harris, Andy, Alavijeh, Mo, Silva-Pedrosa, Rita, Antunes, Sandra, Mauricio, Isabel, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2018

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis

por Van Bocxlaer, Katrien, Caridha, Diana, Black, Chad, Vesely, Brian, Leed, Susan, Sciotti, Richard J., Wijnant, Gert-Jan, Yardley, Vanessa, Braillard, Stéphanie, Mowbray, Charles E., Ioset, Jean-Robert, Croft, Simon L.
Publicado 2019

Favorable Preclinical Pharmacological Profile of a Novel Antimalarial Pyrrolizidinylmethyl Derivative of 4-amino-7-chloroquinoline with Potent In Vitro and In Vivo Activities

por Basilico, Nicoletta, Parapini, Silvia, D’Alessandro, Sarah, Misiano, Paola, Romeo, Sergio, Dondio, Giulio, Yardley, Vanessa, Vivas, Livia, Nasser, Shereen, Rénia, Laurent, Russell, Bruce M., Suwanarusk, Rossarin, Nosten, François, Sparatore, Anna, Taramelli, Donatella
Publicado 2023

An efficient and novel technology for the extraction of parasite genomic DNA from whole blood or culture

por Clark, David J, Moore, Catherine M, Flanagan, Marc, Bocxlaer, Katrien Van, Piperaki, Evangelia-Theophano, Yardley, Vanessa, Croft, Simon L, Tyson, John, Whitehouse, Sam P, O’Halloran, Jonathan, Krishna, Sanjeev, Staines, Henry M
Publicado 2019

Development of (6R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis

por Thompson, Andrew M., O’Connor, Patrick D., Marshall, Andrew J., Blaser, Adrian, Yardley, Vanessa, Maes, Louis, Gupta, Suman, Launay, Delphine, Braillard, Stephanie, Chatelain, Eric, Wan, Baojie, Franzblau, Scott G., Ma, Zhenkun, Cooper, Christopher B., Denny, William A.
Publicado 2018

In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial

por Basilico, Nicoletta, Parapini, Silvia, Sparatore, Anna, Romeo, Sergio, Misiano, Paola, Vivas, Livia, Yardley, Vanessa, Croft, Simon L., Habluetzel, Annette, Lucantoni, Leonardo, Renia, Laurent, Russell, Bruce, Suwanarusk, Rossarin, Nosten, Francois, Dondio, Giulio, Bigogno, Chiara, Jabes, Daniela, Taramelli, Donatella
Publicado 2017

7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis

por Thompson, Andrew M., O’Connor, Patrick D., Marshall, Andrew J., Yardley, Vanessa, Maes, Louis, Gupta, Suman, Launay, Delphine, Braillard, Stephanie, Chatelain, Eric, Franzblau, Scott G., Wan, Baojie, Wang, Yuehong, Ma, Zhenkun, Cooper, Christopher B., Denny, William A.
Publicado 2017

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug

por Sanderson, Lisa, da Silva, Marcelo, Sekhar, Gayathri N., Brown, Rachel C., Burrell-Saward, Hollie, Fidanboylu, Mehmet, Liu, Bo, Dailey, Lea Ann, Dreiss, Cécile A., Lorenz, Chris, Christie, Mark, Persaud, Shanta J., Yardley, Vanessa, Croft, Simon L., Valero, Margarita, Thomas, Sarah A.
Publicado 2021

Visceral Leishmaniasis Patients Display Altered Composition and Maturity of Neutrophils as well as Impaired Neutrophil Effector Functions

por Yizengaw, Endalew, Getahun, Mulusew, Tajebe, Fitsumbrhan, Cruz Cervera, Edward, Adem, Emebet, Mesfin, Getnet, Hailu, Asrat, Van der Auwera, Gert, Yardley, Vanessa, Lemma, Mulualem, Skhedy, Ziv, Diro, Ermias, Yeshanew, Arega, Melkamu, Roma, Mengesha, Bewketu, Modolell, Manuel, Munder, Markus, Müller, Ingrid, Takele, Yegnasew, Kropf, Pascale
Publicado 2016