A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Phase I Study of Analgesic/Antihyperalgesic Properties of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in...

por Schaffler, Klaus, Yassen, Ashraf, Reeh, Peter, Passier, Paul
Publicado 2018

Pharmacokinetic–Pharmacodynamic Modeling of the Effectiveness and Safety of Buprenorphine and Fentanyl in Rats

por Yassen, Ashraf, Olofsen, Erik, Kan, Jingmin, Dahan, Albert, Danhof, Meindert
Publicado 2007

First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development

por Strougo, Ashley, Eissing, Thomas, Yassen, Ashraf, Willmann, Stefan, Danhof, Meindert, Freijer, Jan
Publicado 2012

Pharmacodynamic analysis of the analgesic effect of capsaicin 8% patch (Qutenza™) in diabetic neuropathic pain patients: detection of distinct response groups

por Martini, Christian, Yassen, Ashraf, Olofsen, Erik, Passier, Paul, Stoker, Malcom, Dahan, Albert
Publicado 2012

First evaluation of the safety, pharmacokinetics, and pharmacodynamics of BAY 2433334, a small molecule targeting coagulation factor XIa

por Thomas, Dirk, Kanefendt, Friederike, Schwers, Stephan, Unger, Sigrun, Yassen, Ashraf, Boxnick, Stefanie
Publicado 2021

First randomized evaluation of safety, pharmacodynamics, and pharmacokinetics of BAY 1831865, an antibody targeting coagulation factor XI and factor XIa, in healthy men

por Nowotny, Bettina, Thomas, Dirk, Schwers, Stephan, Wiegmann, Sara, Prange, Wolfgang, Yassen, Ashraf, Boxnick, Stefanie
Publicado 2022

BAY 1213790, a fully human IgG1 antibody targeting coagulation factor XIa: First evaluation of safety, pharmacodynamics, and pharmacokinetics

por Thomas, Dirk, Thelen, Kirstin, Kraff, Stefanie, Schwers, Stephan, Schiffer, Sonja, Unger, Sigrun, Yassen, Ashraf, Boxnick, Stefanie
Publicado 2019

Baseline clusters and the response to positive airway pressure treatment in obstructive sleep apnoea patients: longitudinal data from the European Sleep Apnea Database cohort

por Yassen, Ashraf, Coboeken, Katrin, Bailly, Sébastien, Burghaus, Rolf, Buskova, Jitka, Dogas, Zoran, Drummond, Marta, Gouveris, Haralampos, Joppa, Pavol, Lippert, Joerg, Lombardi, Carolina, Mihaicuta, Stefan, Pépin, Jean Louis, Zou, Ding, Hedner, Jan, Grote, Ludger
Publicado 2022