Tumor regression and immunity in combination therapy with anti-CEA chimeric antigen receptor T cells and anti-CEA-IL2 immunocytokine

por Cha, Seung E., Kujawski, Maciej, J. Yazaki, Paul, Brown, Christine, Shively, John E.
Publicado 2021

Enhanced Therapeutic Effects of (177)Lu-DOTA-M5A in Combination with Heat Shock Protein 90 Inhibitor Onalespib in Colorectal Cancer Xenografts

por Mohajershojai, Tabassom, Spangler, Douglas, Chopra, Saloni, Frejd, Fredrik Y., Yazaki, Paul J., Nestor, Marika
Publicado 2023

In Vitro Characterization of (177)Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer

por Mohajershojai, Tabassom, Jha, Preeti, Boström, Anna, Frejd, Fredrik Y., Yazaki, Paul J., Nestor, Marika
Publicado 2022

Improved targeting of an anti‐TAG‐72 antibody drug conjugate for the treatment of ovarian cancer

por Minnix, Megan, Li, Lin, Yazaki, Paul, Chea, Junie, Poku, Erasmus, Colcher, David, Shively, John E.
Publicado 2020

Near-infrared photoimmunotherapy is effective treatment for colorectal cancer in orthotopic nude-mouse models

por Hollandsworth, Hannah M., Amirfakhri, Siamak, Filemoni, Filemoni, Molnar, Justin, Hoffman, Robert M., Yazaki, Paul, Bouvet, Michael
Publicado 2020

The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review

por Turner, Michael A., Lwin, Thinzar M., Amirfakhri, Siamak, Nishino, Hiroto, Hoffman, Robert M., Yazaki, Paul J., Bouvet, Michael
Publicado 2021

Effective Targeting of TAG72(+) Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells

por Murad, John P., Kozlowska, Anna K., Lee, Hee Jun, Ramamurthy, Maya, Chang, Wen-Chung, Yazaki, Paul, Colcher, David, Shively, John, Cristea, Mihaela, Forman, Stephen J., Priceman, Saul J.
Publicado 2018

Generation of dual specific bivalent BiTEs (dbBIspecific T-cell engaging antibodies) for cellular immunotherapy

por Kujawski, Maciej, Li, Lin, Bhattacharya, Supriyo, Wong, Patty, Lee, Wen-Hui, Williams, Lindsay, Li, Harry, Chea, Junie, Poku, Kofi, Bowles, Nicole, Vaidehi, Nagarajan, Yazaki, Paul, Shively, John E.
Publicado 2019

Multimodality PET and Near-Infrared Fluorescence Intraoperative Imaging of CEA-Positive Colorectal Cancer

por Lwin, Thinzar M., Minnix, Megan, Li, Lin, Sherman, Anakim, Hong, Teresa, Wong, Jeffery Y. C., Olafsen, Tove, Poku, Erasmus, Bouvet, Michael, Fong, Yuman, Shively, John E., Yazaki, Paul J.
Publicado 2023

Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors

por Bäck, Tom A., Jennbacken, Karin, Hagberg Thulin, Malin, Lindegren, Sture, Jensen, Holger, Olafsen, Tove, Yazaki, Paul J., Palm, Stig, Albertsson, Per, Damber, Jan-Erik, Wu, Anna M., Welén, Karin
Publicado 2020

Neural Stem Cells as a Novel Platform for Tumor-Specific Delivery of Therapeutic Antibodies

por Frank, Richard T., Edmiston, Marissa, Kendall, Stephen E., Najbauer, Joseph, Cheung, Chia-Wei, Kassa, Thewodros, Metz, Marianne Z., Kim, Seung U., Glackin, Carlotta A., Wu, Anna M., Yazaki, Paul J., Aboody, Karen S.
Publicado 2009

Improved antibody-guided surgery with a near-infrared dye on a PEGylated linker for CEA-positive tumors

por Yazaki, Paul J., Lwin, Thinzar M., Minnix, Megan, Li, Lin, Sherman, Anakim, Molnar, Justin, Miller, Aaron, Frankel, Paul, Chea, Junie, Poku, Erasmus, Bowles, Nicole, Hoffman, Robert M., Shively, John E., Bouvet, Michael
Publicado 2019

Potent immunomodulatory effects of an anti-CEA-IL-2 immunocytokine on tumor therapy and effects of stereotactic radiation

por Kujawski, Maciej, Sherman, Mark, Hui, Susanta, Zuro, Darren, Lee, Wen-Hui, Yazaki, Paul, Sherman, Anakim, Szpikowska, Barbara, Chea, Junie, Lasiewski, Desiree, Poku, Kofi, Li, Harry, Colcher, David, Wong, Jeffrey, Shively, John E.
Publicado 2020

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model

por Lwin, Thinzar M., Miyake, Kentaro, Murakami, Takashi, DeLong, Jonathan C., Amirfakhri, Siamak, Filemoni, Filemoni, Yoon, Sang Nam, Yazaki, Paul J., Shivley, John E., Datnow, Brian, Clary, Bryan M., Hoffman, Robert M., Bouvet, Michael
Publicado 2018

Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine

por Guan, Min, Lim, Laura, Holguin, Leo, Han, Tianxu, Vyas, Vibhuti, Urak, Ryan, Miller, Aaron, Browning, Diana L., Echavarria, Liliana, Li, Shasha, Li, Shirley, Chang, Wen-Chung, Scott, Tristan, Yazaki, Paul, Morris, Kevin V., Cardoso, Angelo A., Blanchard, M. Suzette, Le Verche, Virginia, Forman, Stephen J., Zaia, John A., Burnett, John C., Wang, Xiuli
Publicado 2022

Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting

por Viola, Domenico, Dona, Ada, Caserta, Enrico, Troadec, Estelle, Besi, Francesca, McDonald, Tinisha, Ghoda, Lucy, Gunes, Emine Gulsen, Sanchez, James F, Khalife, Jihane, Martella, Marianna, Karanes, Chatchada, Htut, Myo, Wang, Xiuli, Rosenzweig, Michael, Chowdhury, Arnab, Sborov, Douglas, Miles, Rodney R, Yazaki, Paul J., Ebner, Todd, Hofmeister, Craig C., Forman, Stephen J, Rosen, Steven T, Marcucci, Guido, Shively, John, Keats, Jonathan J, Krishnan, Amrita, Pichiorri, Flavia
Publicado 2020

Anti-CD25 radioimmunotherapy with BEAM autologous hematopoietic cell transplantation conditioning in Hodgkin lymphoma

por Herrera, Alex F., Palmer, Joycelynne, Adhikarla, Vikram, Yamauchi, Dave, Poku, Erasmus K., Bading, James, Yazaki, Paul, Dandapani, Savita, Mei, Matthew, Chen, Robert, Cao, Thai, Karras, Nicole, McTague, Pamela, Nademanee, Auayporn, Popplewell, Leslie, Sahebi, Firoozeh, Shively, John E., Simpson, Jennifer, Smith, D. Lynne, Song, Joo, Spielberger, Ricardo, Tsai, Ni-Chun, Thomas, Sandra H., Forman, Stephen J., Colcher, David, Wu, Anna M., Wong, Jeffrey, Smith, Eileen
Publicado 2021