Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice

por Zhong, Suyue, Ye, Jinwang, Deng, Yunsong, Zhang, Mohan, Zou, Miaozhan, Yao, Xuanbao, Xiao, Shifeng
Publicado 2023

HDAC7 Activates IKK/NF-κB Signaling to Regulate Astrocyte-Mediated Inflammation

por Ye, Jinwang, Zhong, Suyue, Deng, Yunsong, Yao, Xuanbao, Liu, Qiong, Wang, Jian-Zhi, Xiao, Shifeng
Publicado 2022

Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier

por Liu, Yanchao, Zhang, Shujuan, Li, Xiaoguang, Liu, Enjie, Wang, Xin, Zhou, Qiuzhi, Ye, Jinwang, Wang, Jian-Zhi
Publicado 2020

Tau inhibits PKA by nuclear proteasome‐dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation

por Ye, Jinwang, Yin, Yaling, Liu, Huanhuan, Fang, Lin, Tao, Xiaoqing, Wei, Linyu, Zuo, Yue, Yin, Ying, Ke, Dan, Wang, Jian‐Zhi
Publicado 2019

Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2

por Yin, Yaling, Wang, Yali, Gao, Di, Ye, Jinwang, Wang, Xin, Fang, Lin, Wu, Dongqin, Pi, Guilin, Lu, Chengbiao, Zhou, Xin-Wen, Yang, Ying, Wang, Jian-Zhi
Publicado 2016

Tau‐induced upregulation of C/EBPβ‐TRPC1‐SOCE signaling aggravates tauopathies: A vicious cycle in Alzheimer neurodegeneration

por Ye, Jinwang, Yin, Ying, Yin, Yaling, Zhang, Huaqiu, Wan, Huali, Wang, Lu, Zuo, Yue, Gao, Di, Li, Mengzhu, Li, Jun, Liu, Yanchao, Ke, Dan, Wang, Jian‐Zhi
Publicado 2020

A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models

por Wang, Weijin, Zhou, Qiuzhi, Jiang, Tao, Li, Shihong, Ye, Jinwang, Zheng, Jie, Wang, Xin, Liu, Yanchao, Deng, Minmin, Ke, Dan, Wang, Qun, Wang, Yipeng, Wang, Jian-Zhi
Publicado 2021

Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum–hippocampus cholinergic pathway

por Wu, Dongqin, Gao, Di, Yu, Haitao, Pi, Guilin, Xiong, Rui, Lei, Huiyang, Wang, Xin, Liu, Enjie, Ye, Jinwang, Yu, Huilin, Gao, Yang, He, Ting, Jiang, Tao, Sun, Fei, Su, Jingfen, Song, Guoda, Peng, Wenju, Yang, Ying, Wang, Jian‐Zhi
Publicado 2021

Periphery Biomarkers for Objective Diagnosis of Cognitive Decline in Type 2 Diabetes Patients

por Liu, Yanchao, Zhang, Shujuan, He, Benrong, Chen, Liangkai, Ke, Dan, Zhao, Shi, Zhang, Yao, Wei, Wei, Xu, Zhipeng, Xu, Zihui, Yin, Ying, Mo, Wen, Li, Yanni, Gao, Yang, Li, Shihong, Wang, Weijin, Yu, Huiling, Wu, Dongqin, Pi, Guilin, Jiang, Tao, Deng, Mingmin, Xiong, Rui, Lei, Huiyang, Tian, Na, He, Ting, Sun, Fei, Zhou, Qiuzhi, Wang, Xin, Ye, Jinwang, Li, Mengzhu, Hu, Nan, Song, Guoda, Peng, Wenju, Zheng, Chenghong, Zhang, Huaqiu, Wang, Jian-Zhi
Publicado 2021