Inhibition of IκB kinase in Notch signaling activates FOXO3a

por Ye, Keqiang
Publicado 2012

PIKE GTPase are phosphoinositide-3-kinase enhancers, suppressing programmed cell deathPIKE GTPase are phosphoinositide-3-kinase enhancers, suppressing programmed cell death

por Chan, Chi Bun, Ye, Keqiang, Chan, Chi Bun, Ye, Keqiang
Publicado 2007

The roles of PIKE in tumorigenesis

por Qi, Qi, Ye, Keqiang
Publicado 2013

PIKE GTPase Signaling and Function

por Ahn, Jee-Yin, Ye, Keqiang
Publicado 2005

Multiple Functions of Phosphoinositide-3 Kinase Enhancer (PIKE)

por Chan, Chi Bun, Ye, Keqiang
Publicado 2010

A promising PET tracer candidate targeting α‐synuclein inclusions

por Xiang, Jie, Zhang, Zhentao, Ye, Keqiang
Publicado 2023

δ-secretase in neurodegenerative diseases: mechanisms, regulators and therapeutic opportunities

por Zhang, Zhentao, Tian, Ye, Ye, Keqiang
Publicado 2020

7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders

por Liu, Chaoyang, Chan, Chi Bun, Ye, Keqiang
Publicado 2016

NQO1 Is Regulated by PTEN in Glioblastoma, Mediating Cell Proliferation and Oxidative Stress

por Luo, Shilin, Lei, Kecheng, Xiang, Daxiong, Ye, Keqiang
Publicado 2018

Delta-secretase triggers Alzheimer’s disease pathologies in wild-type hAPP/hMAPT double transgenic mice

por Wu, Zhourui, Liu, Xia, Cheng, Liming, Ye, Keqiang
Publicado 2020

Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer’s disease

por Kang, Seong Su, Ahn, Eun Hee, Ye, Keqiang
Publicado 2020

Akt-phosphorylated PIKE-A inhibits UNC5B-induced apoptosis in cancer cell lines in a p53-dependent manner

por He, Kunyan, Jang, Sung-Wuk, Joshi, Jayashree, Yoo, Min-Heui, Ye, Keqiang
Publicado 2011

7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis

por Xue, Fan, Zhao, Zhenlei, Gu, Yanpei, Han, Jianxin, Ye, Keqiang, Zhang, Ying
Publicado 2021

Asparagine Endopeptidase (δ Secretase), an Enzyme Implicated in Alzheimer’s Disease Pathology, Is an Inhibitor of Axon Regeneration in Peripheral Nerves

por English, Arthur W., Liu, Xia, Mistretta, Olivia C., Ward, Patricia J., Ye, Keqiang
Publicado 2021

C/EBPβ mediates NQO1 and GSTP1 anti-oxidative reductases expression in glioblastoma, promoting brain tumor proliferation

por Lei, Kecheng, Xia, Yiyuan, Wang, Xiao-Chuan, Ahn, Eun Hee, Jin, Lingjing, Ye, Keqiang
Publicado 2020

Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model

por Chen, Chun, Ahn, Eun Hee, Kang, Seong Su, Liu, Xia, Alam, Ashfaqul, Ye, Keqiang
Publicado 2020

Crosstalk between the muscular estrogen receptor α and BDNF/TrkB signaling alleviates metabolic syndrome via 7,8-dihydroxyflavone in female mice

por Zhao, Zhenlei, Xue, Fan, Gu, Yanpei, Han, Jianxin, Jia, Yingxian, Ye, Keqiang, Zhang, Ying
Publicado 2020

A TrkB agonist prodrug prevents bone loss via inhibiting asparagine endopeptidase and increasing osteoprotegerin

por Xiong, Jing, Liao, Jianming, Liu, Xia, Zhang, Zhaohui, Adams, Jonathan, Pacifici, Roberto, Ye, Keqiang
Publicado 2022

Delta-secretase (AEP) mediates tau-splicing imbalance and accelerates cognitive decline in tauopathies

por Wang, Zhi-Hao, Liu, Pai, Liu, Xia, Yu, Shan Ping, Wang, Jian-Zhi, Ye, Keqiang
Publicado 2018

Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinase 4 Triggers Glioblastoma Progression

por Qi, Qi, Kang, Seong-Su, Zhang, Shuai, Pham, Cau, Fu, Haian, Brat, Daniel J., Ye, Keqiang
Publicado 2017