Unveiling the Genetic Architecture of Human Disease for Precision Medicine

por Ramamoorthy, Anuradha, Yee, Sook Wah, Karnes, Jason
Publicado 2018

Genomewide Association Studies in Pharmacogenomics

por McInnes, Gregory, Yee, Sook Wah, Pershad, Yash, Altman, Russ B.
Publicado 2021

Pharmacogene regulatory elements: from discovery to applications

por Smith, Robin P, Lam, Ernest T, Markova, Svetlana, Yee, Sook Wah, Ahituv, Nadav
Publicado 2012

The Impacts of Slc19a3 Deletion and Intestinal SLC19A3 Insertion on Thiamine Distribution and Brain Metabolism in the Mouse

por Wen, Anita, Zhu, Ying, Yee, Sook Wah, Park, Brian I., Giacomini, Kathleen M., Greenberg, Andrew S., Newman, John W.
Publicado 2023

Profiling Solute Carrier Transporters in the Human Blood-Brain Barrier

por Geier, Ethan G., Chen, Eugene C., Webb, Amy, Papp, Audrey C., Yee, Sook Wah, Sadee, Wolfgang, Giacomini, Kathleen M.
Publicado 2013

High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3

por Chen, Eugene C., Matsson, Pär, Azimi, Mina, Zhou, Xujia, Handin, Niklas, Yee, Sook Wah, Artursson, Per, Giacomini, Kathleen M.
Publicado 2022

The Effects of Genetic Mutations and Drugs on the Activity of the Thiamine Transporter, SLC19A2

por Enogieru, Osatohanmwen J., Koleske, Megan L., Vora, Bianca, Ngo, Huy, Yee, Sook Wah, Chatad, Derrick, Sirota, Marina, Giacomini, Kathleen M.
Publicado 2021

Discovery of Regulatory Elements in Human ATP-Binding Cassette Transporters through Expression Quantitative Trait Mapping

por Matsson, Pär, Yee, Sook Wah, Markova, Svetlana, Morrissey, Kari, Jenkins, Gerard, Xuan, Jiekun, Jorgenson, Eric, Kroetz, Deanna L., Giacomini, Kathleen M.
Publicado 2011

Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug–Drug Interaction and Associated Biomarker Levels in Healthy Volunteers

por Yee, Sook Wah, Giacomini, Marilyn M., Shen, Hong, Humphreys, W. Griffith, Horng, Howard, Brian, William, Lai, Yurong, Kroetz, Deanna L., Giacomini, Kathleen M.
Publicado 2019

GenEpi: gene-based epistasis discovery using machine learning

por Chang, Yu-Chuan, Wu, June-Tai, Hong, Ming-Yi, Tung, Yi-An, Hsieh, Ping-Han, Yee, Sook Wah, Giacomini, Kathleen M., Oyang, Yen-Jen, Chen, Chien-Yu
Publicado 2020

Drugs in COVID‐19 Clinical Trials: Predicting Transporter‐Mediated Drug‐Drug Interactions Using In Vitro Assays and Real‐World Data

por Yee, Sook Wah, Vora, Bianca, Oskotsky, Tomiko, Zou, Ling, Jakobsen, Sebastian, Enogieru, Osatohanmwen J., Koleske, Megan L., Kosti, Idit, Rödin, Mattias, Sirota, Marina, Giacomini, Kathleen M.
Publicado 2021

Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia

por Yee, Sook Wah, Mefford, Joel A., Singh, Natasha, Percival, Mary-Elizabeth, Stecula, Adrian, Yang, Kuo, Witte, John S., Takahashi, Atsushi, Kubo, Michiaki, Matsuda, Koichi, Giacomini, Kathleen M., Andreadis, Charalambos
Publicado 2013

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans

por Rotroff, Daniel M., Oki, Noffisat O., Liang, Xiaomin, Yee, Sook Wah, Stocker, Sophie L., Corum, Daniel G., Meisner, Michele, Fiehn, Oliver, Motsinger-Reif, Alison A., Giacomini, Kathleen M., Kaddurah-Daouk, Rima
Publicado 2016

The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics

por Yee, Sook Wah, Macdonald, Christian, Mitrovic, Darko, Zhou, Xujia, Koleske, Megan L., Yang, Jia, Silva, Dina Buitrago, Grimes, Patrick Rockefeller, Trinidad, Donovan, More, Swati S., Kachuri, Linda, Witte, John S., Delemotte, Lucie, Giacomini, Kathleen M., Coyote-Maestas, Willow
Publicado 2023

Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content

por Liang, Xiaomin, Yee, Sook Wah, Chien, Huan-Chieh, Chen, Eugene C., Luo, Qi, Zou, Ling, Piao, Meiling, Mifune, Arias, Chen, Ligong, Calvert, Meredith E., King, Sarah, Norheim, Frode, Abad, Janna, Krauss, Ronald M., Giacomini, Kathleen M.
Publicado 2018

Genetic and Epigenetic Regulation of the Organic Cation Transporter 3, SLC22A3

por Chen, Ligong, Hong, Chibo, Chen, Eugene C., Yee, Sook Wah, Xu, Lu, Almof, Emil U., Wen, Christopher, Fujii, Kacyn, Johns, Susan J., Stryke, Doug, Ferrin, Thomas E., Simko, Jeff, Chen, Xin, Costello, Joseph F., Giacomini, Kathleen M.
Publicado 2012

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies

por Yee, Sook Wah, Stecula, Adrian, Chien, Huan-Chieh, Zou, Ling, Feofanova, Elena V., van Borselen, Marjolein, Cheung, Kit Wun Kathy, Yousri, Noha A., Suhre, Karsten, Kinchen, Jason M., Boerwinkle, Eric, Irannejad, Roshanak, Yu, Bing, Giacomini, Kathleen M.
Publicado 2019

Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue

por Song, Wenxin, Luo, Qi, Zhang, Yuping, Zhou, Linkang, Liu, Ye, Ma, Zhilong, Guo, Jianan, Huang, Yuedong, Cheng, Lili, Meng, Ziyi, Li, Zicheng, Zhang, Bin, Li, Siqi, Yee, Sook Wah, Fan, Hao, Li, Peng, Giacomini, Kathleen M., Chen, Ligong
Publicado 2019

Genomic Characterization of Metformin Hepatic Response

por Luizon, Marcelo R., Eckalbar, Walter L., Wang, Yao, Jones, Stacy L., Smith, Robin P., Laurance, Megan, Lin, Lawrence, Gallins, Paul J., Etheridge, Amy S., Wright, Fred, Zhou, Yihui, Molony, Cliona, Innocenti, Federico, Yee, Sook Wah, Giacomini, Kathleen M., Ahituv, Nadav
Publicado 2016

Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children's Oncology Group

por DuBois, Steven G., Geier, Ethan, Batra, Vandana, Yee, Sook Wah, Neuhaus, John, Segal, Mark, Martinez, Daniel, Pawel, Bruce, Yanik, Greg, Naranjo, Arlene, London, Wendy B., Kreissman, Susan, Baker, David, Attiyeh, Edward, Hogarty, Michael D., Maris, John M., Giacomini, Kathleen, Matthay, Katherine K.
Publicado 2012