Mechanism of Bidirectional Leading-Strand Synthesis Establishment at Eukaryotic DNA Replication Origins

por Aria, Valentina, Yeeles, Joseph T.P.
Publicado 2019

The eukaryotic replisome tolerates leading‐strand base damage by replicase switching

por Guilliam, Thomas A, Yeeles, Joseph TP
Publicado 2021

The Initial Response of a Eukaryotic Replisome to DNA Damage

por Taylor, Martin R.G., Yeeles, Joseph T.P.
Publicado 2018

Dynamics of Replication Fork Progression Following Helicase–Polymerase Uncoupling in Eukaryotes

por Taylor, Martin R.G., Yeeles, Joseph T.P.
Publicado 2019

Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

por Deegan, Tom D, Yeeles, Joseph TP, Diffley, John FX
Publicado 2016

How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication

por Jones, Morgan L., Aria, Valentina, Baris, Yasemin, Yeeles, Joseph T.P.
Publicado 2023

CST–Polymeraseα-primase solves a second telomere end-replication problem

por Takai, Hiro, Aria, Valentina, Borges, Pamela, Yeeles, Joseph T. P., de Lange, Titia
Publicado 2023

The AddAB helicase–nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain

por Yeeles, Joseph T.P., Gwynn, Emma J., Webb, Martin R., Dillingham, Mark S.
Publicado 2011

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication

por Yeeles, Joseph T.P., Janska, Agnieska, Early, Anne, Diffley, John F.X.
Publicado 2017

CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis

por Ratnayeke, Nalin, Baris, Yasemin, Chung, Mingyu, Yeeles, Joseph T.P., Meyer, Tobias
Publicado 2023

Structure of a human replisome shows the organisation and interactions of a DNA replication machine

por Jones, Morgan L, Baris, Yasemin, Taylor, Martin R G, Yeeles, Joseph T P
Publicado 2021

Insights into Chi recognition from the structure of an AddAB-type helicase–nuclease complex

por Saikrishnan, Kayarat, Yeeles, Joseph T, Gilhooly, Neville S, Krajewski, Wojciech W, Dillingham, Mark S, Wigley, Dale B
Publicado 2012

Regulated Eukaryotic DNA Replication Origin Firing with Purified Proteins

por Yeeles, Joseph T.P., Deegan, Tom D., Janska, Agnieszka, Early, Anne, Diffley, John F. X.
Publicado 2015

Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

por Kurat, Christoph F., Yeeles, Joseph T.P., Patel, Harshil, Early, Anne, Diffley, John F.X.
Publicado 2017

Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork

por Baretić, Domagoj, Jenkyn-Bedford, Michael, Aria, Valentina, Cannone, Giuseppe, Skehel, Mark, Yeeles, Joseph T.P.
Publicado 2020

Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes

por Deegan, Tom D., Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T.P., Labib, Karim P.M.
Publicado 2019

A conserved mechanism for regulating replisome disassembly in eukaryotes

por Jenkyn-Bedford, Michael, Jones, Morgan L., Baris, Yasemin, Labib, Karim P. M., Cannone, Giuseppe, Yeeles, Joseph T. P., Deegan, Tom D.
Publicado 2021

DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in C. elegans

por Xia, Yisui, Sonneville, Remi, Jenkyn-Bedford, Michael, Ji, Liqin, Alabert, Constance, Hong, Ye, Yeeles, Joseph T.P., Labib, Karim P.M.
Publicado 2023

Visualizing helicases unwinding DNA at the single molecule level

por Fili, Natali, Mashanov, Gregory I., Toseland, Christopher P., Batters, Christopher, Wallace, Mark I., Yeeles, Joseph T. P., Dillingham, Mark S., Webb, Martin R., Molloy, Justin E.
Publicado 2010

Replication‐induced DNA secondary structures drive fork uncoupling and breakage

por Williams, Sophie L, Casas‐Delucchi, Corella S, Raguseo, Federica, Guneri, Dilek, Li, Yunxuan, Minamino, Masashi, Fletcher, Emma E, Yeeles, Joseph TP, Keyser, Ulrich F, Waller, Zoë AE, Di Antonio, Marco, Coster, Gideon
Publicado 2023