Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks

por Rees, Holly A., Yeh, Wei-Hsi, Liu, David R.
Publicado 2019

In vivo base editing of post-mitotic sensory cells

por Yeh, Wei-Hsi, Chiang, Hao, Rees, Holly A., Edge, Albert S. B., Liu, David R.
Publicado 2018

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery

por Rees, Holly A., Komor, Alexis C., Yeh, Wei-Hsi, Caetano-Lopes, Joana, Warman, Matthew, Edge, Albert S. B., Liu, David R.
Publicado 2017

Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning

por Chen, Jonathan C., Chen, Jonathan P., Shen, Max W., Wornow, Michael, Bae, Minwoo, Yeh, Wei-Hsi, Hsu, Alvin, Liu, David R.
Publicado 2022

Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells

por Wu, Chen-Chi, Brugeaud, Aurore, Seist, Richard, Lin, Hsiao-Chun, Yeh, Wei-Hsi, Petrillo, Marco, Coppola, Giovanni, Edge, Albert S. B., Stankovic, Konstantina M.
Publicado 2020

Treatment of Tumors with Vitamin E Suppresses Myeloid Derived Suppressor Cells and Enhances CD8+ T Cell-Mediated Antitumor Effects

por Kang, Tae Heung, Knoff, Jayne, Yeh, Wei-Hsi, Yang, Benjamin, Wang, Chenguang, Kim, Young Seob, Kim, Tae Woo, Wu, Tzyy-Choou, Hung, Chien-Fu
Publicado 2014

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses

por Levy, Jonathan M., Yeh, Wei-Hsi, Pendse, Nachiket, Davis, Jessie R., Hennessey, Erin, Butcher, Rossano, Koblan, Luke W., Comander, Jason, Liu, Qin, Liu, David R.
Publicado 2020

Continuous evolution of base editors with expanded target compatibility and improved activity

por Thuronyi, Benjamin W., Koblan, Luke W., Levy, Jonathan M., Yeh, Wei-Hsi, Zheng, Christine, Newby, Gregory A., Wilson, Christopher, Bhaumik, Mantu, Shubina-Oleinik, Olga, Holt, Jeffrey R., Liu, David R.
Publicado 2019

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents

por Gao, Xue, Tao, Yong, Lamas, Veronica, Huang, Mingqian, Yeh, Wei-Hsi, Pan, Bifeng, Hu, Yu-Juan, Hu, Johnny H., Thompson, David B., Shu, Yilai, Li, Yamin, Wang, Hongyang, Yang, Shiming, Xu, Qiaobing, Polley, Daniel B., Liberman, M. Charles, Kong, Wei-Jia, Holt, Jeffrey R., Chen, Zheng-Yi, Liu, David R.
Publicado 2017