Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1

por Yu, Shibing, Yerges-Armstrong, Laura M., Chu, Yanxia, Zmuda, Joseph M., Zhang, Yingze
Publicado 2016

Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis

por Tise, Christina G., Anforth, Leslie E., Zhou, Albert E., Perry, James A., McArdle, Patrick F., Streeten, Elizabeth A., Shuldiner, Alan R., Yerges-Armstrong, Laura M.
Publicado 2017

Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation

por Salimi, Shabnam, Lewis, Joshua P., Yerges‐Armstrong, Laura M., Mitchell, Braxton D., Saeed, Faisal, O'Connell, Jeffry R., Perry, James A., Ryan, Kathleen A., Shuldiner, Alan R., Parsa, Afshin
Publicado 2016

A Common Variant in the SETD7 Gene Predicts Serum Lycopene Concentrations

por D’Adamo, Christopher R., D’Urso, Antonietta, Ryan, Kathleen A., Yerges-Armstrong, Laura M., Semba, Richard D., Steinle, Nanette I., Mitchell, Braxton D., Shuldiner, Alan R., McArdle, Patrick F.
Publicado 2016

From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases

por Tise, Christina G., Perry, James A., Anforth, Leslie E., Pavlovich, Mary A., Backman, Joshua D., Ryan, Kathleen A., Lewis, Joshua P., O’Connell, Jeffrey R., Yerges-Armstrong, Laura M., Shuldiner, Alan R.
Publicado 2016

Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed-Pharmacogenomics

por Yerges-Armstrong, Laura M., Ellero-Simatos, Sandrine, Georgiades, Anastasia, Zhu, Hongjie, Lewis, Joshua, Horenstein, Richard B., Beitelshees, Amber L., Dane, Adrie, Reijmers, Theo, Hankemeier, Thomas, Fiehn, Oliver, Shuldiner, Alan R., Kaddurah-Daouk, Rima
Publicado 2013

Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes

por Aponte, Jennifer L, Chiano, Mathias N, Yerges-Armstrong, Laura M, Hinds, David A, Tian, Chao, Gupta, Akanksha, Guo, Cong, Fraser, Dana J, Freudenberg, Johannes M, Rajpal, Deepak K, Ehm, Margaret G, Waterworth, Dawn M
Publicado 2018

Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction

por Fisch, Adam S., Yerges-Armstrong, Laura M., Backman, Joshua D., Wang, Hong, Donnelly, Patrick, Ryan, Kathleen A., Parihar, Ankita, Pavlovich, Mary A., Mitchell, Braxton D., O’Connell, Jeffrey R., Herzog, William, Harman, Christopher R., Wren, Jonathan D., Lewis, Joshua P.
Publicado 2015

Oxylipid Profile of Low‐Dose Aspirin Exposure: A Pharmacometabolomics Study

por Ellero‐Simatos, Sandrine, Beitelshees, Amber L., Lewis, Joshua P., Yerges‐Armstrong, Laura M., Georgiades, Anastasia, Dane, Adrie, Harms, Amy C., Strassburg, Katrin, Guled, Faisa, Hendriks, Margriet M. W. B., Horenstein, Richard B., Shuldiner, Alan R., Hankemeier, Thomas, Kaddurah‐Daouk, Rima
Publicado 2015

Pleiotropic associations of heterozygosity for the SERPINA1 Z allele in the UK Biobank

por Fawcett, Katherine A., Song, Kijoung, Qian, Guoqing, Farmaki, Aliki-Eleni, Packer, Richard, John, Catherine, Shrine, Nick, Granell, Raquel, Ring, Sue, Timpson, Nicholas J., Yerges-Armstrong, Laura M., Eastell, Richard, Wain, Louise V., Scott, Robert A., Tobin, Martin D., Hall, Ian P.
Publicado 2021

Phenome-wide association study using research participants’ self-reported data provides insight into the Th17 and IL-17 pathway

por Ehm, Margaret G., Aponte, Jennifer L., Chiano, Mathias N., Yerges-Armstrong, Laura M., Johnson, Toby, Barker, Jonathan N., Cook, Suzanne F., Gupta, Akanksha, Hinds, David A., Li, Li, Nelson, Matthew R., Simpson, Michael A., Tian, Chao, McCarthy, Linda C., Rajpal, Deepak K., Waterworth, Dawn M.
Publicado 2017

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

por Tachmazidou, Ioanna, Dedoussis, George, Southam, Lorraine, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Xifara, Dionysia K., Matchan, Angela, Hatzikotoulas, Konstantinos, Rayner, Nigel W., Chen, Yuan, Pollin, Toni I., O’Connell, Jeffrey R., Yerges-Armstrong, Laura M., Kiagiadaki, Chrysoula, Panoutsopoulou, Kalliope, Schwartzentruber, Jeremy, Moutsianas, Loukas, Tsafantakis, Emmanouil, Tyler-Smith, Chris, McVean, Gil, Xue, Yali, Zeggini, Eleftheria
Publicado 2013

Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes

por Barata, Llilda, Feitosa, Mary F., Bielak, Lawrence F., Halligan, Brian, Baldridge, Abigail S., Guo, Xiuqing, Yerges‐Armstrong, Laura M., Smith, Albert V., Yao, Jie, Palmer, Nicholette D., VanWagner, Lisa B., Carr, J. Jeffrey, Chen, Yii‐Der I., Allison, Matthew, Budoff, Matthew J., Handelman, Samuel K., Kardia, Sharon L.R., Mosley, Thomas H., Ryan, Kathleen, Harris, Tamara B., Launer, Lenore J., Gudnason, Vilmundur, Rotter, Jerome I., Fornage, Myriam, Rasmussen‐Torvik, Laura J., Borecki, Ingrid B., O’Connell, Jeffrey R., Peyser, Patricia A., Speliotes, Elizabeth K., Province, Michael A.
Publicado 2019

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

por Speliotes, Elizabeth K., Yerges-Armstrong, Laura M., Wu, Jun, Hernaez, Ruben, Kim, Lauren J., Palmer, Cameron D., Gudnason, Vilmundur, Eiriksdottir, Gudny, Garcia, Melissa E., Launer, Lenore J., Nalls, Michael A., Clark, Jeanne M., Mitchell, Braxton D., Shuldiner, Alan R., Butler, Johannah L., Tomas, Marta, Hoffmann, Udo, Hwang, Shih-Jen, Massaro, Joseph M., O'Donnell, Christopher J., Sahani, Dushyant V., Salomaa, Veikko, Schadt, Eric E., Schwartz, Stephen M., Siscovick, David S., Voight, Benjamin F., Carr, J. Jeffrey, Feitosa, Mary F., Harris, Tamara B., Fox, Caroline S., Smith, Albert V., Kao, W. H. Linda, Hirschhorn, Joel N., Borecki, Ingrid B.
Publicado 2011

WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk

por Zheng, Hou-Feng, Tobias, Jon H., Duncan, Emma, Evans, David M., Eriksson, Joel, Paternoster, Lavinia, Yerges-Armstrong, Laura M., Lehtimäki, Terho, Bergström, Ulrica, Kähönen, Mika, Leo, Paul J., Raitakari, Olli, Laaksonen, Marika, Nicholson, Geoffrey C., Viikari, Jorma, Ladouceur, Martin, Lyytikäinen, Leo-Pekka, Medina-Gomez, Carolina, Rivadeneira, Fernando, Prince, Richard L., Sievanen, Harri, Leslie, William D., Mellström, Dan, Eisman, John A., Movérare-Skrtic, Sofia, Goltzman, David, Hanley, David A., Jones, Graeme, St. Pourcain, Beate, Xiao, Yongjun, Timpson, Nicholas J., Smith, George Davey, Reid, Ian R., Ring, Susan M., Sambrook, Philip N., Karlsson, Magnus, Dennison, Elaine M., Kemp, John P., Danoy, Patrick, Sayers, Adrian, Wilson, Scott G., Nethander, Maria, McCloskey, Eugene, Vandenput, Liesbeth, Eastell, Richard, Liu, Jeff, Spector, Tim, Mitchell, Braxton D., Streeten, Elizabeth A., Brommage, Robert, Pettersson-Kymmer, Ulrika, Brown, Matthew A., Ohlsson, Claes, Richards, J. Brent, Lorentzon, Mattias
Publicado 2012

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts

por Vimaleswaran, Karani S., Berry, Diane J., Lu, Chen, Tikkanen, Emmi, Pilz, Stefan, Hiraki, Linda T., Cooper, Jason D., Dastani, Zari, Li, Rui, Houston, Denise K., Wood, Andrew R., Michaëlsson, Karl, Vandenput, Liesbeth, Zgaga, Lina, Yerges-Armstrong, Laura M., McCarthy, Mark I., Dupuis, Josée, Kaakinen, Marika, Kleber, Marcus E., Jameson, Karen, Arden, Nigel, Raitakari, Olli, Viikari, Jorma, Lohman, Kurt K., Ferrucci, Luigi, Melhus, Håkan, Ingelsson, Erik, Byberg, Liisa, Lind, Lars, Lorentzon, Mattias, Salomaa, Veikko, Campbell, Harry, Dunlop, Malcolm, Mitchell, Braxton D., Herzig, Karl-Heinz, Pouta, Anneli, Hartikainen, Anna-Liisa, Streeten, Elizabeth A., Theodoratou, Evropi, Jula, Antti, Wareham, Nicholas J., Ohlsson, Claes, Frayling, Timothy M., Kritchevsky, Stephen B., Spector, Timothy D., Richards, J. Brent, Lehtimäki, Terho, Ouwehand, Willem H., Kraft, Peter, Cooper, Cyrus, März, Winfried, Power, Chris, Loos, Ruth J. F., Wang, Thomas J., Järvelin, Marjo-Riitta, Whittaker, John C., Hingorani, Aroon D., Hyppönen, Elina
Publicado 2013

Rare coding variants and X-linked loci associated with age at menarche

por Lunetta, Kathryn L., Day, Felix R., Sulem, Patrick, Ruth, Katherine S., Tung, Joyce Y., Hinds, David A., Esko, Tõnu, Elks, Cathy E., Altmaier, Elisabeth, He, Chunyan, Huffman, Jennifer E., Mihailov, Evelin, Porcu, Eleonora, Robino, Antonietta, Rose, Lynda M., Schick, Ursula M., Stolk, Lisette, Teumer, Alexander, Thompson, Deborah J., Traglia, Michela, Wang, Carol A., Yerges-Armstrong, Laura M., Antoniou, Antonis C., Barbieri, Caterina, Coviello, Andrea D., Cucca, Francesco, Demerath, Ellen W., Dunning, Alison M., Gandin, Ilaria, Grove, Megan L., Gudbjartsson, Daniel F., Hocking, Lynne J., Hofman, Albert, Huang, Jinyan, Jackson, Rebecca D., Karasik, David, Kriebel, Jennifer, Lange, Ethan M., Lange, Leslie A., Langenberg, Claudia, Li, Xin, Luan, Jian'an, Mägi, Reedik, Morrison, Alanna C., Padmanabhan, Sandosh, Pirie, Ailith, Polasek, Ozren, Porteous, David, Reiner, Alex P., Rivadeneira, Fernando, Rudan, Igor, Sala, Cinzia F., Schlessinger, David, Scott, Robert A., Stöckl, Doris, Visser, Jenny A., Völker, Uwe, Vozzi, Diego, Wilson, James G., Zygmunt, Marek, Boerwinkle, Eric, Buring, Julie E., Crisponi, Laura, Easton, Douglas F., Hayward, Caroline, Hu, Frank B., Liu, Simin, Metspalu, Andres, Pennell, Craig E., Ridker, Paul M., Strauch, Konstantin, Streeten, Elizabeth A., Toniolo, Daniela, Uitterlinden, André G., Ulivi, Sheila, Völzke, Henry, Wareham, Nicholas J., Wellons, Melissa, Franceschini, Nora, Chasman, Daniel I., Thorsteinsdottir, Unnur, Murray, Anna, Stefansson, Kari, Murabito, Joanne M., Ong, Ken K., Perry, John R. B.
Publicado 2015

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

por Lunetta, Kathryn L., Day, Felix R., Sulem, Patrick, Ruth, Katherine S., Tung, Joyce Y., Hinds, David A., Esko, Tõnu, Elks, Cathy E., Altmaier, Elisabeth, He, Chunyan, Huffman, Jennifer E., Mihailov, Evelin, Porcu, Eleonora, Robino, Antonietta, Rose, Lynda M., Schick, Ursula M., Stolk, Lisette, Teumer, Alexander, Thompson, Deborah J., Traglia, Michela, Wang, Carol A., Yerges-Armstrong, Laura M., Antoniou, Antonis C., Barbieri, Caterina, Coviello, Andrea D., Cucca, Francesco, Demerath, Ellen W., Dunning, Alison M., Gandin, Ilaria, Grove, Megan L., Gudbjartsson, Daniel F., Hocking, Lynne J., Hofman, Albert, Huang, Jinyan, Jackson, Rebecca D., Karasik, David, Kriebel, Jennifer, Lange, Ethan M., Lange, Leslie A., Langenberg, Claudia, Li, Xin, Luan, Jian'an, Mägi, Reedik, Morrison, Alanna C., Padmanabhan, Sandosh, Pirie, Ailith, Polasek, Ozren, Porteous, David, Reiner, Alex P., Rivadeneira, Fernando, Rudan, Igor, Sala, Cinzia F., Schlessinger, David, Scott, Robert A., Stöckl, Doris, Visser, Jenny A., Völker, Uwe, Vozzi, Diego, Wilson, James G., Zygmunt, Marek, Boerwinkle, Eric, Buring, Julie E., Crisponi, Laura, Easton, Douglas F., Hayward, Caroline, Hu, Frank B., Liu, Simin, Metspalu, Andres, Pennell, Craig E., Ridker, Paul M., Strauch, Konstantin, Streeten, Elizabeth A., Toniolo, Daniela, Uitterlinden, André G., Ulivi, Sheila, Völzke, Henry, Wareham, Nicholas J., Wellons, Melissa, Franceschini, Nora, Chasman, Daniel I., Thorsteinsdottir, Unnur, Murray, Anna, Stefansson, Kari, Murabito, Joanne M., Ong, Ken K., Perry, John R. B.
Publicado 2015

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

por Shrine, Nick, Guyatt, Anna L, Erzurumluoglu, A Mesut, Jackson, Victoria E, Hobbs, Brian D, Melbourne, Carl A, Batini, Chiara, Fawcett, Katherine A, Song, Kijoung, Sakornsakolpat, Phuwanat, Li, Xingnan, Boxall, Ruth, Reeve, Nicola F, Obeidat, Ma’en, Zhao, Jing Hua, Wielscher, Matthias, Weiss, Stefan, Kentistou, Katherine A, Cook, James P, Sun, Benjamin B, Zhou, Jian, Hui, Jennie, Karrasch, Stefan, Imboden, Medea, Harris, Sarah E, Marten, Jonathan, Enroth, Stefan, Kerr, Shona M, Surakka, Ida, Vitart, Veronique, Lehtimäki, Terho, Allen, Richard J, Bakke, Per S, Beaty, Terri H, Bleecker, Eugene R, Bossé, Yohan, Brandsma, Corry-Anke, Chen, Zhengming, Crapo, James D, Danesh, John, DeMeo, Dawn L, Dudbridge, Frank, Ewert, Ralf, Gieger, Christian, Gulsvik, Amund, Hansell, Anna L, Hao, Ke, Hoffman, Joshua D, Hokanson, John E, Homuth, Georg, Joshi, Peter K, Joubert, Philippe, Langenberg, Claudia, Li, Xuan, Li, Liming, Lin, Kuang, Lind, Lars, Locantore, Nicholas, Luan, Jian’an, Mahajan, Anubha, Maranville, Joseph C, Murray, Alison, Nickle, David C, Packer, Richard, Parker, Margaret M, Paynton, Megan L, Porteous, David J, Prokopenko, Dmitry, Qiao, Dandi, Rawal, Rajesh, Runz, Heiko, Sayers, Ian, Sin, Don D, Smith, Blair H, Artigas, María Soler, Sparrow, David, Tal-Singer, Ruth, Timmers, Paul RHJ, Van den Berge, Maarten, Whittaker, John C, Woodruff, Prescott G, Yerges-Armstrong, Laura M, Troyanskaya, Olga G, Raitakari, Olli T, Kähönen, Mika, Polasek, Ozren, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J, Probst-Hensch, Nicole M, Schulz, Holger, James, Alan L, Wilson, James F, Stubbe, Beate, Zeggini, Eleftheria, Jarvelin, Marjo-Riitta, Wareham, Nick, Silverman, Edwin K, Hayward, Caroline, Morris, Andrew P, Butterworth, Adam S, Scott, Robert A, Walters, Robin G, Meyers, Deborah A, Cho, Michael H, Strachan, David P, Hall, Ian P, Tobin, Martin D, Wain, Louise V
Publicado 2019

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

por Shah, Sonia, Henry, Albert, Roselli, Carolina, Lin, Honghuang, Sveinbjörnsson, Garðar, Fatemifar, Ghazaleh, Hedman, Åsa K., Wilk, Jemma B., Morley, Michael P., Chaffin, Mark D., Helgadottir, Anna, Verweij, Niek, Dehghan, Abbas, Almgren, Peter, Andersson, Charlotte, Aragam, Krishna G., Ärnlöv, Johan, Backman, Joshua D., Biggs, Mary L., Bloom, Heather L., Brandimarto, Jeffrey, Brown, Michael R., Buckbinder, Leonard, Carey, David J., Chasman, Daniel I., Chen, Xing, Chen, Xu, Chung, Jonathan, Chutkow, William, Cook, James P., Delgado, Graciela E., Denaxas, Spiros, Doney, Alexander S., Dörr, Marcus, Dudley, Samuel C., Dunn, Michael E., Engström, Gunnar, Esko, Tõnu, Felix, Stephan B., Finan, Chris, Ford, Ian, Ghanbari, Mohsen, Ghasemi, Sahar, Giedraitis, Vilmantas, Giulianini, Franco, Gottdiener, John S., Gross, Stefan, Guðbjartsson, Daníel F., Gutmann, Rebecca, Haggerty, Christopher M., van der Harst, Pim, Hyde, Craig L., Ingelsson, Erik, Jukema, J. Wouter, Kavousi, Maryam, Khaw, Kay-Tee, Kleber, Marcus E., Køber, Lars, Koekemoer, Andrea, Langenberg, Claudia, Lind, Lars, Lindgren, Cecilia M., London, Barry, Lotta, Luca A., Lovering, Ruth C., Luan, Jian’an, Magnusson, Patrik, Mahajan, Anubha, Margulies, Kenneth B., März, Winfried, Melander, Olle, Mordi, Ify R., Morgan, Thomas, Morris, Andrew D., Morris, Andrew P., Morrison, Alanna C., Nagle, Michael W., Nelson, Christopher P., Niessner, Alexander, Niiranen, Teemu, O’Donoghue, Michelle L., Owens, Anjali T., Palmer, Colin N. A., Parry, Helen M., Perola, Markus, Portilla-Fernandez, Eliana, Psaty, Bruce M., Rice, Kenneth M., Ridker, Paul M., Romaine, Simon P. R., Rotter, Jerome I., Salo, Perttu, Salomaa, Veikko, van Setten, Jessica, Shalaby, Alaa A., Smelser, Diane T., Smith, Nicholas L., Stender, Steen, Stott, David J., Svensson, Per, Tammesoo, Mari-Liis, Taylor, Kent D., Teder-Laving, Maris, Teumer, Alexander, Thorgeirsson, Guðmundur, Thorsteinsdottir, Unnur, Torp-Pedersen, Christian, Trompet, Stella, Tyl, Benoit, Uitterlinden, Andre G., Veluchamy, Abirami, Völker, Uwe, Voors, Adriaan A., Wang, Xiaosong, Wareham, Nicholas J., Waterworth, Dawn, Weeke, Peter E., Weiss, Raul, Wiggins, Kerri L., Xing, Heming, Yerges-Armstrong, Laura M., Yu, Bing, Zannad, Faiez, Zhao, Jing Hua, Hemingway, Harry, Samani, Nilesh J., McMurray, John J. V., Yang, Jian, Visscher, Peter M., Newton-Cheh, Christopher, Malarstig, Anders, Holm, Hilma, Lubitz, Steven A., Sattar, Naveed, Holmes, Michael V., Cappola, Thomas P., Asselbergs, Folkert W., Hingorani, Aroon D., Kuchenbaecker, Karoline, Ellinor, Patrick T., Lang, Chim C., Stefansson, Kari, Smith, J. Gustav, Vasan, Ramachandran S., Swerdlow, Daniel I., Lumbers, R. Thomas
Publicado 2020