IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma()

por Wan, Xiaolin, Yeung, Choh, Heske, Christine, Mendoza, Arnulfo, Helman, Lee J.
Publicado 2015

Autocrine Transforming Growth Factor-β Growth Pathway in Murine Osteosarcoma Cell Lines Associated with Inability to Affect Phosphorylation of Retinoblastoma Protein

por Navid, Fariba, Letterio, John J., Yeung, Choh L., Pegtel, Michiel, Helman, Lee J.
Publicado 2000

The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma()

por Heske, Christine M., Yeung, Choh, Mendoza, Arnulfo, Baumgart, Joshua T., Edessa, Leah D., Wan, Xiaolin, Helman, Lee J.
Publicado 2016

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma

por Gibson, Anna E., Yeung, Choh, Issaq, Sameer H., Collins, Victor J., Gouzoulis, Michael, Zhang, Yiping, Ji, Jiuping, Mendoza, Arnulfo, Heske, Christine M.
Publicado 2020

Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin

por Wan, Xiaolin, Kim, Su Young, Guenther, Lillian M, Mendoza, Arnulfo, Briggs, Joseph, Yeung, Choh, Currier, Duane, Zhang, Hua, Mackall, Crystal, Li, Wan-Ju, Tuan, Rocky S, Deyrup, Andrea T, Khanna, Chand, Helman, Lee
Publicado 2009