Vitamin K3 derivative induces apoptotic cell death in neuroblastoma via downregulation of MYCN expression

por Yoda, Hiroyuki, Nakayama, Toshimitsu, Miura, Motofumi, Toriyama, Masaharu, Motohashi, Shigeyasu, Suzuki, Takashi
Publicado 2019

Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides

por Ota, Yoko, Yoda, Hiroyuki, Inoue, Takahiro, Watanabe, Takayoshi, Shinozaki, Yoshinao, Takatori, Atsushi, Nagase, Hiroki
Publicado 2021

Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity

por Ozaki, Toshinori, Sugimoto, Hirokazu, Nakamura, Mizuyo, Hiraoka, Kiriko, Yoda, Hiroyuki, Sang, Meixiang, Fujiwara, Kyoko, Nagase, Hiroki
Publicado 2015

Depletion of pro-oncogenic RUNX2 enhances gemcitabine (GEM) sensitivity of p53-mutated pancreatic cancer Panc-1 cells through the induction of pro-apoptotic TAp63

por Ozaki, Toshinori, Nakamura, Mizuyo, Ogata, Takehiro, Sang, Meijie, Yoda, Hiroyuki, Hiraoka, Kiriko, Sang, Meixiang, Shimozato, Osamu
Publicado 2016

Depletion of runt-related transcription factor 2 (RUNX2) enhances SAHA sensitivity of p53-mutated pancreatic cancer cells through the regulation of mutant p53 and TAp63

por Ogata, Takehiro, Nakamura, Mizuyo, Sang, Meijie, Yoda, Hiroyuki, Hiraoka, Kiriko, Yin, Danjing, Sang, Mexiang, Shimozato, Osamu, Ozaki, Toshinori
Publicado 2017

Estimating genome-wide off-target effects for pyrrole-imidazole polyamide binding by a pathway-based expression profiling approach

por Lin, Jason, Krishnamurthy, Sakthisri, Yoda, Hiroyuki, Shinozaki, Yoshinao, Watanabe, Takayoshi, Koshikawa, Nobuko, Takatori, Atsushi, Horton, Paul, Nagase, Hiroki
Publicado 2019

CD133 prevents colon cancer cell death induced by serum deprivation through activation of Akt‐mediated protein synthesis and inhibition of apoptosis

por Mori, Yusuke, Takeuchi, Ayaka, Miyagawa, Kengo, Yoda, Hiroyuki, Soda, Hiroaki, Nabeya, Yoshihiro, Watanabe, Naoko, Ozaki, Toshinori, Shimozato, Osamu
Publicado 2021

Targeting the mutant PIK3CA gene by DNA‐alkylating pyrrole‐imidazole polyamide in cervical cancer

por Krishnamurthy, Sakthisri, Yoda, Hiroyuki, Hiraoka, Kiriko, Inoue, Takahiro, Lin, Jason, Shinozaki, Yoshinao, Watanabe, Takayoshi, Koshikawa, Nobuko, Takatori, Atsushi, Nagase, Hiroki
Publicado 2021

Use of DNA‐alkylating pyrrole‐imidazole polyamides for anti‐cancer drug sensitivity screening in pancreatic ductal adenocarcinoma

por Tsujimoto, Akiko, Matsuo, Niina, Lai, Xiaoyi, Inoue, Takahiro, Yoda, Hiroyuki, Lin, Jason, Shinozaki, Yoshinao, Watanabe, Takayoshi, Koshikawa, Nobuko, Takatori, Atsushi, Nagase, Hiroki
Publicado 2022

PTPRK suppresses progression and chemo‐resistance of colon cancer cells via direct inhibition of pro‐oncogenic CD133

por Matsushita, Masashi, Mori, Yusuke, Uchiumi, Kyosuke, Ogata, Takehiro, Nakamura, Mizuyo, Yoda, Hiroyuki, Soda, Hiroaki, Takiguchi, Nobuhiro, Nabeya, Yoshihiro, Shimozato, Osamu, Ozaki, Toshinori
Publicado 2019