AIM2 Inflammasome-Mediated Pyroptosis in Enterovirus A71-Infected Neuronal Cells Restricts Viral Replication

por Yogarajah, Thinesshwary, Ong, Kien Chai, Perera, David, Wong, Kum Thong
Publicado 2017

Drug repurposing of pyrimidine analogs as potent antiviral compounds against human enterovirus A71 infection with potential clinical applications

por Sun, Jialei, Yogarajah, Thinesshwary, Lee, Regina Ching Hua, Kaur, Parveen, Inoue, Masafumi, Tan, Yong Wah, Chu, Justin Jang Hann
Publicado 2020

Electrostatic interactions at the five-fold axis alter heparin-binding phenotype and drive enterovirus A71 virulence in mice

por Tee, Han Kang, Tan, Chee Wah, Yogarajah, Thinesshwary, Lee, Michelle Hui Pheng, Chai, Hann Juang, Hanapi, Nur Aziah, Yusof, Siti R., Ong, Kien Chai, Lee, Vannajan Sanghiran, Sam, I-Ching, Chan, Yoke Fun
Publicado 2019

The host-targeting compound peruvoside has a broad-spectrum antiviral activity against positive-sense RNA viruses

por Wu, Kan Xing, Yogarajah, Thinesshwary, Loe, Marcus Wing Choy, Kaur, Parveen, Lee, Regina Ching Hua, Mok, Chee Keng, Wong, Yi Hao, Phuektes, Patchara, Yeo, Li Sze, Chow, Vincent T.K., Tan, Yong Wah, Chu, Justin Jang Hann
Publicado 2023

AAV-CRISPR-Cas13 eliminates human enterovirus and prevents death of infected mice

por Keng, Choong Tat, Yogarajah, Thinesshwary, Lee, Regina Ching Hua, Muhammad, Irfan Bin Hajis, Chia, Bing Shao, Vasandani, Suraj Rajan, Lim, Daryl Shern, Guo, Ke, Wong, Yi Hao, Mok, Chee Keng, Chu, Justin Jang Hann, Chew, Wei Leong
Publicado 2023

A single-dose live attenuated chimeric vaccine candidate against Zika virus

por Chin, Wei-Xin, Lee, Regina Ching Hua, Kaur, Parveen, Lew, Tian Sheng, Yogarajah, Thinesshwary, Kong, Hao Yuin, Teo, Zi-Yun, Salim, Cyrill Kafi, Zhang, Rong-Rong, Li, Xiao-Feng, Alonso, Sylvie, Qin, Cheng-Feng, Chu, Justin Jang Hann
Publicado 2021

Flavivirus genome recoding by codon optimisation confers genetically stable in vivo attenuation in both mice and mosquitoes

por Chin, Wei-Xin, Kong, Hao Yuin, Zhu, Isabelle Xin Yu, Teo, Zi Yun, Faruk, Regina, Lee, Regina Ching Hua, Ho, Si Xian, Aw, Zhen Qin, Yi, Bowen, Hou, Xin Jun, Tan, Antson Kiat Yee, Yogarajah, Thinesshwary, Huber, Roland G., Cai, Yu, Wan, Yue, Chu, Justin Jang Hann
Publicado 2023