The RASopathies: from pathogenetics to therapeutics

por Hebron, Katie E., Hernandez, Edjay Ralph, Yohe, Marielle E.
Publicado 2022

Kras activation in p53-deficient myoblasts results in high-grade sarcoma formation with impaired myogenic differentiation

por McKinnon, Timothy, Venier, Rosemarie, Dickson, Brendan C., Kabaroff, Leah, Alkema, Manon, Chen, Li, Shern, Jack F., Yohe, Marielle E., Khan, Javed, Gladdy, Rebecca A.
Publicado 2015

Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1

por Soubias, Olivier, Pant, Shashank, Heinrich, Frank, Zhang, Yue, Roy, Neeladri Sekhar, Li, Jess, Jian, Xiaoying, Yohe, Marielle E., Randazzo, Paul A., Lösche, Mathias, Tajkhorshid, Emad, Byrd, R. Andrew
Publicado 2020

Clonality and Evolutionary History of Rhabdomyosarcoma

por Chen, Li, Shern, Jack F., Wei, Jun S., Yohe, Marielle E., Song, Young K., Hurd, Laura, Liao, Hongling, Catchpoole, Daniel, Skapek, Stephen X., Barr, Frederic G., Hawkins, Douglas S., Khan, Javed
Publicado 2015

CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG

por Liu, Zhihui, Zhang, Xiyuan, Lei, Haiyan, Lam, Norris, Carter, Sakereh, Yockey, Oliver, Xu, Max, Mendoza, Arnulfo, Hernandez, Edjay R., Wei, Jun S., Khan, Javed, Yohe, Marielle E., Shern, Jack F., Thiele, Carol J.
Publicado 2020

ARF GTPases and their GEFs and GAPs: concepts and challenges

por Sztul, Elizabeth, Chen, Pei-Wen, Casanova, James E., Cherfils, Jacqueline, Dacks, Joel B., Lambright, David G., Lee, Fang-Jen S., Randazzo, Paul A., Santy, Lorraine C., Schürmann, Annette, Wilhelmi, Ilka, Yohe, Marielle E., Kahn, Richard A.
Publicado 2019

The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins

por Rosenberg, Eric M., Jian, Xiaoying, Soubias, Olivier, Yoon, Hye-Young, Yadav, Mukesh P., Hammoudeh, Sarah, Pallikkuth, Sandeep, Akpan, Itoro, Chen, Pei-Wen, Maity, Tapan K., Jenkins, Lisa M., Yohe, Marielle E., Byrd, R. Andrew, Randazzo, Paul A.
Publicado 2023

Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma

por Odeniyide, Patience, Yohe, Marielle E., Pollard, Kai, Vaseva, Angelina V., Calizo, Ana, Zhang, Lindy, Rodriguez, Fausto J., Gross, John M., Allen, Amy N., Wan, Xiaolin, Somwar, Romel, Schreck, Karisa C., Kessler, Linda, Wang, Jiawan, Pratilas, Christine A.
Publicado 2022

Correction: Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma

por Odeniyide, Patience, Yohe, Marielle E., Pollard, Kai, Vaseva, Angelina V., Calizo, Ana, Zhang, Lindy, Rodriguez, Fausto J., Gross, John M., Allen, Amy N., Wan, Xiaolin, Somwar, Romel, Schreck, Karisa C., Kessler, Linda, Wang, Jiawan, Pratilas, Christine A.
Publicado 2022

Chemical genomics reveals histone deacetylases are required for core regulatory transcription

por Gryder, Berkley E., Wu, Lei, Woldemichael, Girma M., Pomella, Silvia, Quinn, Taylor R., Park, Paul M. C., Cleveland, Abigail, Stanton, Benjamin Z., Song, Young, Rota, Rossella, Wiest, Olaf, Yohe, Marielle E., Shern, Jack F., Qi, Jun, Khan, Javed
Publicado 2019

Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor

por Zhang, Xiyuan, Lou, Hannah E., Gopalan, Vishaka, Liu, Zhihui, Jafarah, Hilda M., Lei, Haiyan, Jones, Paige, Sayers, Carly M., Yohe, Marielle E., Chittiboina, Prashant, Widemann, Brigitte C., Thiele, Carol J., Kelly, Michael C., Hannenhalli, Sridhar, Shern, Jack F.
Publicado 2022

Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

por Pomella, Silvia, Sreenivas, Prethish, Gryder, Berkley E., Wang, Long, Milewski, David, Cassandri, Matteo, Baxi, Kunal, Hensch, Nicole R., Carcarino, Elena, Song, Young, Chou, Hsien-Chao, Yohe, Marielle E., Stanton, Benjamin Z., Amadio, Bruno, Caruana, Ignazio, De Stefanis, Cristiano, De Vito, Rita, Locatelli, Franco, Chen, Yidong, Chen, Eleanor Y., Houghton, Peter, Khan, Javed, Rota, Rossella, Ignatius, Myron S.
Publicado 2021

Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma

por Bogen, Dominik, Wei, Jun S., Azorsa, David O., Ormanoglu, Pinar, Buehler, Eugen, Guha, Rajarshi, Keller, Jonathan M., Griner, Lesley A. Mathews, Ferrer, Marc, Song, Young K., Liao, Hongling, Mendoza, Arnulfo, Gryder, Berkley E., Sindri, Sivasish, He, Jianbin, Wen, Xinyu, Zhang, Shile, Shern, John F., Yohe, Marielle E., Taschner-Mandl, Sabine, Shohet, Jason M., Thomas, Craig J., Martin, Scott E., Ambros, Peter F., Khan, Javed
Publicado 2015

Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium

por Shern, Jack F., Selfe, Joanna, Izquierdo, Elisa, Patidar, Rajesh, Chou, Hsien-Chao, Song, Young K., Yohe, Marielle E., Sindiri, Sivasish, Wei, Jun, Wen, Xinyu, Rudzinski, Erin R., Barkauskas, Donald A., Lo, Tammy, Hall, David, Linardic, Corinne M., Hughes, Debbie, Jamal, Sabri, Jenney, Meriel, Chisholm, Julia, Brown, Rebecca, Jones, Kristine, Hicks, Belynda, Angelini, Paola, George, Sally, Chesler, Louis, Hubank, Michael, Kelsey, Anna, Gatz, Susanne A., Skapek, Stephen X., Hawkins, Douglas S., Shipley, Janet M., Khan, Javed
Publicado 2021

Immuno-transcriptomic profiling of extracranial pediatric solid malignancies

por Brohl, Andrew S., Sindiri, Sivasish, Wei, Jun S., Milewski, David, Chou, Hsien-Chao, Song, Young K., Wen, Xinyu, Kumar, Jeetendra, Reardon, Hue V., Mudunuri, Uma S., Collins, Jack R., Nagaraj, Sushma, Gangalapudi, Vineela, Tyagi, Manoj, Zhu, Yuelin J., Masih, Katherine E., Yohe, Marielle E., Shern, Jack F., Qi, Yue, Guha, Udayan, Catchpoole, Daniel, Orentas, Rimas J., Kuznetsov, Igor B., Llosa, Nicolas J., Ligon, John A., Turpin, Brian K., Leino, Daniel G., Iwata, Shintaro, Andrulis, Irene L., Wunder, Jay S., Toledo, Silvia R.C., Meltzer, Paul S., Lau, Ching, Teicher, Beverly A., Magnan, Heather, Ladanyi, Marc, Khan, Javed
Publicado 2021