The SK-N-AS human neuroblastoma cell line develops osteolytic bone metastases with increased angiogenesis and COX-2 expression

por Tsutsumimoto, Takahiro, Williams, Paul, Yoneda, Toshiyuki
Publicado 2014

Sensory nerves: A driver of the vicious cycle in bone metastasis?

por Yoneda, Toshiyuki, Hiasa, Masahiro, Okui, Tatsuo, Hata, Kenji
Publicado 2021

The acid-sensing nociceptor TRPV1 controls breast cancer progression in bone via regulating HGF secretion from sensory neurons

por OKUI, TATSUO, Hiasa, Masahiro, Hata, Kenji, Roodman, G David, Nakanishi, Masako, Yoneda, Toshiyuki
Publicado 2023

Stathmin is involved in the cooperative effect of Zoledronic acid and gefitinib on bone homing breast cancer cells in vitro

por Oda, Miki, Iwaya, Keiichi, Kikuchi, Ryoko, Kobayashi, Takayuki, Yoneda, Toshiyuki, Nishikawa, Kahoko, Matsubara, Osamu, Kohno, Norio
Publicado 2012

The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer

por Ishihara, Shota, Hata, Kenji, Hirose, Katsutoshi, Okui, Tatsuo, Toyosawa, Satoru, Uzawa, Narikazu, Nishimura, Riko, Yoneda, Toshiyuki
Publicado 2022

Acid Activation of Trpv1 Leads to an Up-Regulation of Calcitonin Gene-related Peptide Expression in Dorsal Root Ganglion Neurons via the CaMK-CREB Cascade: A Potential Mechanism of...

por Nakanishi, Masako, Hata, Kenji, Nagayama, Tomotaka, Sakurai, Teruhisa, Nishisho, Toshihiko, Wakabayashi, Hiroki, Hiraga, Toru, Ebisu, Shigeyuki, Yoneda, Toshiyuki
Publicado 2010

Lactate secreted via MCT4 from bone-colonizing breast cancer excites sensory neurons via GPR81

por Okui, Tatsuo, Hiasa, Masahiro, Hasegawa, Kazuaki, Nakamura, Tomoya, Ono, Kisho, Ibaragi, Soichiro, Kanno, Takahiro, Sasaki, Akira, Yoneda, Toshiyuki
Publicado 2023

Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose–response study of AMG 162 (Denosumab) in patients with RheumatoId arthritis on methotrexate to Validate i...

por Takeuchi, Tsutomu, Tanaka, Yoshiya, Ishiguro, Naoki, Yamanaka, Hisashi, Yoneda, Toshiyuki, Ohira, Takeshi, Okubo, Naoki, Genant, Harry K, van der Heijde, Désirée
Publicado 2016

Efficacy of denosumab with regard to bone destruction in prognostic subgroups of Japanese rheumatoid arthritis patients from the phase II DRIVE study

por Ishiguro, Naoki, Tanaka, Yoshiya, Yamanaka, Hisashi, Yoneda, Toshiyuki, Ohira, Takeshi, Okubo, Naoki, Genant, Harry K, van der Heijde, Désirée, Takeuchi, Tsutomu
Publicado 2019

Cadherin-6 Mediates the Heterotypic Interactions between the Hemopoietic Osteoclast Cell Lineage and Stromal Cells in a Murine Model of Osteoclast Differentiation

por Mbalaviele, Gabriel, Nishimura, Riko, Myoi, Akira, Niewolna, Maria, Reddy, Sakamuri V., Chen, Di, Feng, Jian, Roodman, David, Mundy, Gregory R., Yoneda, Toshiyuki
Publicado 1998

The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

por Okui, Tatsuo, Hiasa, Masahiro, Ryumon, Shoji, Ono, Kisho, Kunisada, Yuki, Ibaragi, Soichiro, Sasaki, Akira, Roodman, G. David, White, Fletcher A., Yoneda, Toshiyuki
Publicado 2020

Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic dr...

por Takeuchi, Tsutomu, Tanaka, Yoshiya, Soen, Satoshi, Yamanaka, Hisashi, Yoneda, Toshiyuki, Tanaka, Sakae, Nitta, Takaya, Okubo, Naoki, Genant, Harry K, van der Heijde, Désirée
Publicado 2019

Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription

por Amano, Katsuhiko, Hata, Kenji, Muramatsu, Shuji, Wakabayashi, Makoto, Takigawa, Yoko, Ono, Koichiro, Nakanishi, Masako, Takashima, Rikako, Kogo, Mikihiko, Matsuda, Akio, Nishimura, Riko, Yoneda, Toshiyuki
Publicado 2011

Identifying the preferable rheumatoid arthritis subgroups for intervention with the anti-RANKL antibody denosumab to reduce progression of joint destruction

por Tanaka, Yoshiya, Soen, Satoshi, Ishiguro, Naoki, Yamanaka, Hisashi, Yoneda, Toshiyuki, Tanaka, Sakae, Ohira, Takeshi, Nitta, Takaya, Okubo, Naoki, Genant, Harry, van der Heijde, Desirée, Takeuchi, Tsutomu
Publicado 2020

Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2

por Ono, Koichiro, Hata, Kenji, Nakamura, Eriko, Ishihara, Shota, Kobayashi, Sachi, Nakanishi, Masako, Yoshida, Michiko, Takahata, Yoshifumi, Murakami, Tomohiko, Takenoshita, Seiichi, Komori, Toshihisa, Nishimura, Riko, Yoneda, Toshiyuki
Publicado 2021

Decreased C-Src Expression Enhances Osteoblast Differentiation and Bone Formation

por Marzia, Marilena, Sims, Natalie A., Voit, Susanne, Migliaccio, Silvia, Taranta, Anna, Bernardini, Silvia, Faraggiana, Tullio, Yoneda, Toshiyuki, Mundy, Gregory R., Boyce, Brendan F., Baron, Roland, Teti, Anna
Publicado 2000

Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging

por Davis, Hannah M., Pacheco‐Costa, Rafael, Atkinson, Emily G., Brun, Lucas R., Gortazar, Arancha R., Harris, Julia, Hiasa, Masahiro, Bolarinwa, Surajudeen A., Yoneda, Toshiyuki, Ivan, Mircea, Bruzzaniti, Angela, Bellido, Teresita, Plotkin, Lilian I.
Publicado 2017

Clinical Trials Express: Fracture Risk Reduction With Denosumab in Japanese Postmenopausal Women and Men With Osteoporosis: Denosumab Fracture Intervention Randomized Placebo Contr...

por Nakamura, Toshitaka, Matsumoto, Toshio, Sugimoto, Toshitsugu, Hosoi, Takayuki, Miki, Takami, Gorai, Itsuo, Yoshikawa, Hideki, Tanaka, Yoshiya, Tanaka, Sakae, Sone, Teruki, Nakano, Tetsuo, Ito, Masako, Matsui, Shigeyuki, Yoneda, Toshiyuki, Takami, Hideo, Watanabe, Ko, Osakabe, Taisuke, Shiraki, Masataka, Fukunaga, Masao
Publicado 2014

Japanese Expert Panel Meeting on the Management of Prostate Cancer with Bone Metastases

por Takahashi, Shunji, Kinuya, Seigo, Nonomura, Norio, Shinohara, Nobuo, Suzuki, Kazuhiro, Suzuki, Hiroyoshi, Nakamura, Katsumasa, Satoh, Takefumi, Tateishi, Ukihide, Yoneda, Toshiyuki, Horikoshi, Hiroyuki, Igawa, Tsukasa, Kamai, Takao, Koizumi, Mitsuru, Kosaka, Takeo, Matsubara, Nobuaki, Miyake, Hideaki, Mizokami, Atsushi, Mizowaki, Takashi, Nakamura, Naoki, Nozawa, Masahiro, Takahashi, Takeo, Uemura, Hiroji, Uemura, Motohide, Yokomizo, Akira, Yoshimura, Mana, Kakehi, Yoshiyuki
Publicado 2018