Effects of combinations of gapmer antisense oligonucleotides on the target reduction

por Yanagidaira, Mitsugu, Yoshioka, Kotaro, Nagata, Tetsuya, Nakao, Shoichi, Miyata, Kenichi, Yokota, Takanori
Publicado 2023

Separation-related rapid nuclear transport of DNA/RNA heteroduplex oligonucleotide: unveiling distinctive intracellular trafficking

por Ono, Daisuke, Asada, Ken, Yui, Daishi, Sakaue, Fumika, Yoshioka, Kotaro, Nagata, Tetsuya, Yokota, Takanori
Publicado 2020

2′,4′‐BNA/LNA with 9‐(2‐Aminoethoxy)‐1,3‐diaza‐2‐oxophenoxazine Efficiently Forms Duplexes and Has Enhanced Enzymatic Resistance

por Kishimoto, Yuki, Nakagawa, Osamu, Fujii, Akane, Yoshioka, Kotaro, Nagata, Tetsuya, Yokota, Takanori, Hari, Yoshiyuki, Obika, Satoshi
Publicado 2020

Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo

por Asami, Yutaro, Nagata, Tetsuya, Yoshioka, Kotaro, Kunieda, Taiki, Yoshida-Tanaka, Kie, Bennett, C. Frank, Seth, Punit P., Yokota, Takanori
Publicado 2021

Change of intracellular calcium level causes acute neurotoxicity by antisense oligonucleotides via CSF route

por Jia, Chunyan, Lei Mon, Su Su, Yang, Ying, Katsuyama, Maho, Yoshida-Tanaka, Kie, Nagata, Tetsuya, Yoshioka, Kotaro, Yokota, Takanori
Publicado 2022

Effective silencing of miR-126 after ischemic stroke by means of intravenous α-tocopherol–conjugated heteroduplex oligonucleotide in mice

por Suzuki, Motohiro, Ishibashi, Satoru, Iwasawa, Eri, Oguma, Takahiro, Saito, Yasuhiro, Li, Fuying, Otsu, Shinichi, Ichinose, Keiko, Yoshioka, Kotaro, Nagata, Tetsuya, Yokota, Takanori
Publicado 2021

Highly efficient silencing of microRNA by heteroduplex oligonucleotides

por Yoshioka, Kotaro, Kunieda, Taiki, Asami, Yutaro, Guo, Huijia, Miyata, Haruka, Yoshida-Tanaka, Kie, Sujino, Yumiko, Piao, Wenying, Kuwahara, Hiroya, Nishina, Kazutaka, Hara, Rintaro Iwata, Nagata, Tetsuya, Wada, Takeshi, Obika, Satoshi, Yokota, Takanori
Publicado 2019

Progressive Encephalomyelitis with Rigidity and Myoclonus Resolving after Thymectomy with Subsequent Anasarca: An Autopsy Case

por Ozaki, Kokoro, Ohkubo, Takuya, Yamada, Tetsuo, Yoshioka, Kotaro, Ichijo, Masahiko, Majima, Takamasa, Kudo, Shunsuke, Akashi, Takumi, Honda, Keiji, Ito, Eisaku, Watanabe, Mayumi, Sekine, Masaki, Hamagaki, Miwako, Eishi, Yoshinobu, Sanjo, Nobuo, Ishibashi, Satoru, Mizusawa, Hidehiro, Yokota, Takanori
Publicado 2018

DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing

por Nishina, Kazutaka, Piao, Wenying, Yoshida-Tanaka, Kie, Sujino, Yumiko, Nishina, Tomoko, Yamamoto, Tsuyoshi, Nitta, Keiko, Yoshioka, Kotaro, Kuwahara, Hiroya, Yasuhara, Hidenori, Baba, Takeshi, Ono, Fumiko, Miyata, Kanjiro, Miyake, Koichi, Seth, Punit P., Low, Audrey, Yoshida, Masayuki, Bennett, C. Frank, Kataoka, Kazunori, Mizusawa, Hidehiro, Obika, Satoshi, Yokota, Takanori
Publicado 2015