Sugar and fat – that's where it's at: metabolic changes in tumors

por Young, Christian D, Anderson, Steven M
Publicado 2008

Rah, rah, ROS: metabolic changes caused by loss of adhesion induce cell death

por Young, Christian D, Anderson, Steven M
Publicado 2009

Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers

por Young, Christian D., Arteaga, Carlos L., Cook, Rebecca S.
Publicado 2015

Transforming Growth Factor-β Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts

por Shi, Xueke, Young, Christian D., Zhou, Hongmei, Wang, Xiao-Jing
Publicado 2020

Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3

por Young, Christian D, Nolte, Erica C, Lewis, Andrew, Serkova, Natalie J, Anderson, Steven M
Publicado 2008

mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis

por Morrison, Meghan M., Young, Christian D., Wang, Shan, Sobolik, Tammy, Sanchez, Violeta M., Hicks, Donna J., Cook, Rebecca S., Brantley-Sieders, Dana M.
Publicado 2015

Polymorphonuclear myeloid-derived suppressor cells and phosphatidylinositol-3 kinase gamma are critical to tobacco-mimicking oral carcinogenesis in mice

por Nguyen, Khoa A, DePledge, Lisa N, Bian, Li, Ke, Yao, Samedi, Von, Berning, Amber A, Owens, Philip, Wang, Xiao-Jing, Young, Christian D
Publicado 2023

Cancer-Associated Fibroblasts Facilitate Squamous Cell Carcinoma Lung Metastasis in Mice by Providing TGFβ-Mediated Cancer Stem Cell Niche

por Shi, Xueke, Luo, Jingjing, Weigel, Kelsey J., Hall, Spencer C., Du, Danfeng, Wu, Fanglong, Rudolph, Michael C., Zhou, Hongmei, Young, Christian D., Wang, Xiao-Jing
Publicado 2021

Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo

por Young, Christian D., Lewis, Andrew S., Rudolph, Michael C., Ruehle, Marisa D., Jackman, Matthew R., Yun, Ui J., Ilkun, Olesya, Pereira, Renata, Abel, E. Dale, Anderson, Steven M.
Publicado 2011

Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis

por Morrison Joly, Meghan, Williams, Michelle M., Hicks, Donna J., Jones, Bayley, Sanchez, Violeta, Young, Christian D., Sarbassov, Dos D., Muller, William J., Brantley-Sieders, Dana, Cook, Rebecca S.
Publicado 2017

Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFβ/PD-L1 blockade-treated squamous cell carcinoma

por Strait, Alexander A., Woolaver, Rachel A., Hall, Spencer C., Young, Christian D., Karam, Sana D., Jimeno, Antonio, Lan, Yan, Raben, David, Wang, Jing H., Wang, Xiao-Jing
Publicado 2021

Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15(+) Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma

por Chen, Samantha M. Y., Bian, Li, Nicklawsky, Andrew G., Krinsky, Alexandra L., Brunetti, Tonya, Woolaver, Rachel A., Wang, Xiaoguang, Chen, Zhangguo, Young, Christian D., Gao, Dexiang, Wang, Xiao-Jing, Wang, Jing H.
Publicado 2020