Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes

por Young, George R, Mavrommatis, Bettina, Kassiotis, George
Publicado 2014

Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice

por Young, George R, Kassiotis, George, Stoye, Jonathan P
Publicado 2012

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis

por Young, George R, Stoye, Jonathan P, Kassiotis, George
Publicado 2013

Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes

por Attig, Jan, Young, George R., Stoye, Jonathan P., Kassiotis, George
Publicado 2017

Antibody-induced internalisation of retroviral envelope glycoproteins is a signal initiation event

por Panova, Veera, Attig, Jan, Young, George R., Stoye, Jonathan P., Kassiotis, George
Publicado 2020

Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses

por Yap, Melvyn W., Young, George R., Varnaite, Renata, Morand, Serge, Stoye, Jonathan P.
Publicado 2020

Resurrection of endogenous retroviruses in antibody-deficient mice

por Young, George R, Eksmond, Urszula, Salcedo, Rosalba, Alexopoulou, Lena, Stoye, Jonathan P, Kassiotis, George
Publicado 2012

Structure of Drosophila melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag

por Cottee, Matthew A., Letham, Suzanne C., Young, George R., Stoye, Jonathan P., Taylor, Ian A.
Publicado 2020

Negative Selection by an Endogenous Retrovirus Promotes a Higher-Avidity CD4(+) T Cell Response to Retroviral Infection

por Young, George R., Ploquin, Mickaël J.-Y., Eksmond, Urszula, Wadwa, Munisch, Stoye, Jonathan P., Kassiotis, George
Publicado 2012

Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist

por Ng, Kevin W, Attig, Jan, Young, George R, Ottina, Eleonora, Papamichos, Spyros I, Kotsianidis, Ioannis, Kassiotis, George
Publicado 2019

SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export

por Hall, Ross, Guedán, Anabel, Yap, Melvyn W., Young, George R., Harvey, Ruth, Stoye, Jonathan P., Bishop, Kate N.
Publicado 2022

Gv1, a Zinc Finger Gene Controlling Endogenous MLV Expression

por Young, George R, Ferron, Aaron K W, Panova, Veera, Eksmond, Urszula, Oliver, Peter L, Kassiotis, George, Stoye, Jonathan P
Publicado 2021

Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retroelement co-option

por Ng, Kevin W., Attig, Jan, Bolland, William, Young, George R., Major, Jack, Wrobel, Antoni G., Gamblin, Steve, Wack, Andreas, Kassiotis, George
Publicado 2020

LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly

por Attig, Jan, Young, George R., Hosie, Louise, Perkins, David, Encheva-Yokoya, Vesela, Stoye, Jonathan P., Snijders, Ambrosius P., Ternette, Nicola, Kassiotis, George
Publicado 2019

The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes

por Kazachenka, Anastasiya, Loong, Jane Hc, Attig, Jan, Young, George R, Ganguli, Piyali, Devonshire, Ginny, Grehan, Nicola, Ciccarelli, Francesca D, Fitzgerald, Rebecca C, Kassiotis, George
Publicado 2023

Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control

por Cottee, Matthew A., Beckwith, Sean L., Letham, Suzanne C., Kim, Sarah J., Young, George R., Stoye, Jonathan P., Garfinkel, David J., Taylor, Ian A.
Publicado 2021

Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression

por Kazachenka, Anastasiya, Young, George R., Attig, Jan, Kordella, Chrysoula, Lamprianidou, Eleftheria, Zoulia, Emmanuela, Vrachiolias, George, Papoutselis, Menelaos, Bernard, Elsa, Papaemmanuil, Elli, Kotsianidis, Ioannis, Kassiotis, George
Publicado 2019

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses

por Tang, Qiannan, Rigby, Rachel E., Young, George R., Hvidt, Astrid Korning, Davis, Tanja, Tan, Tiong Kit, Bridgeman, Anne, Townsend, Alain R., Kassiotis, George, Rehwinkel, Jan
Publicado 2021

Z-nucleic acid sensing triggers ZBP1-dependent necroptosis and inflammation

por Jiao, Huipeng, Wachsmuth, Laurens, Kumari, Snehlata, Schwarzer, Robin, Lin, Juan, Eren, Remzi Onur, Fisher, Amanda, Lane, Rebecca, Young, George R., Kassiotis, George, Kaiser, William J., Pasparakis, Manolis
Publicado 2020

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus

por Donnarumma, Tiziano, Young, George R., Merkenschlager, Julia, Eksmond, Urszula, Bongard, Nadine, Nutt, Stephen L., Boyer, Claude, Dittmer, Ulf, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko, Bayer, Wibke, Kassiotis, George
Publicado 2016