The methyl binding domain containing protein MBD5 is a transcriptional regulator responsible for 2q23.1 deletion syndrome

por Walz, Katherina, Young, Juan I
Publicado 2014

DNA Methyltransferase I (DNMT1) Inhibition Induces a p21 Dependent Cell Cycle Arrest

por Young, Juan I., Smith, James R.
Publicado 2001

Unconventional Transcriptional Response to Environmental Enrichment in a Mouse Model of Rett Syndrome

por Kerr, Bredford, Silva, Pamela A., Walz, Katherina, Young, Juan I.
Publicado 2010

DNA Methylation Variation Is Identified in Monozygotic Twins Discordant for Non-syndromic Cleft Lip and Palate

por Young, Juan I., Slifer, Susan, Hecht, Jacqueline T., Blanton, Susan H.
Publicado 2021

MethReg: estimating the regulatory potential of DNA methylation in gene transcription

por Silva, Tiago C, Young, Juan I, Martin, Eden R, Chen, X Steven, Wang, Lily
Publicado 2022

Rai1 Haploinsufficiency Is Associated with Social Abnormalities in Mice

por Rao, Nalini R., Abad, Clemer, Perez, Irene C., Srivastava, Anand K., Young, Juan I., Walz, Katherina
Publicado 2017

RAI1 Transcription Factor Activity Is Impaired in Mutants Associated with Smith-Magenis Syndrome

por Carmona-Mora, Paulina, Canales, Cesar P., Cao, Lei, Perez, Irene C., Srivastava, Anand K., Young, Juan I., Walz, Katherina
Publicado 2012

Disruption of Mbd5 in mice causes neuronal functional deficits and neurobehavioral abnormalities consistent with 2q23.1 microdeletion syndrome

por Camarena, Vladimir, Cao, Lei, Abad, Clemer, Abrams, Alexander, Toledo, Yaima, Araki, Kimi, Araki, Masatake, Walz, Katherina, Young, Juan I
Publicado 2014

Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival

por Kannan-Sundhari, Abhiraami, Abad, Clemer, Maloof, Marie E., Ayad, Nagi G., Young, Juan I., Liu, Xue Zhong, Walz, Katherina
Publicado 2020

Functional and cellular characterization of human Retinoic Acid Induced 1 (RAI1) mutations associated with Smith-Magenis Syndrome

por Carmona-Mora, Paulina, Encina, Carolina A, Canales, Cesar P, Cao, Lei, Molina, Jessica, Kairath, Pamela, Young, Juan I, Walz, Katherina
Publicado 2010

Distinct CSF biomarker-associated DNA methylation in Alzheimer’s disease and cognitively normal subjects

por Zhang, Wei, Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Lukacsovich, David, Varma, Achintya, Chen, X. Steven, Martin, Eden R., Wang, Lily
Publicado 2023

Sex-specific DNA methylation differences in Alzheimer’s disease pathology

por Zhang, Lanyu, Young, Juan I., Gomez, Lissette, Silva, Tiago C., Schmidt, Michael A., Cai, Jesse, Chen, Xi, Martin, Eden R., Wang, Lily
Publicado 2021

Distinct CSF biomarker-associated DNA methylation in Alzheimer’s disease and cognitively normal subjects

por Zhang, Wei, Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Lukacsovich, David, Varma, Achintya, Chen, X. Steven, Martin, Eden R., Wang, Lily
Publicado 2023

Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease

por C. Silva, Tiago, Young, Juan I., Zhang, Lanyu, Gomez, Lissette, Schmidt, Michael A., Varma, Achintya, Chen, X. Steven, Martin, Eden R., Wang, Lily
Publicado 2022

Distinct sex-specific DNA methylation differences in Alzheimer’s disease

por C. Silva, Tiago, Zhang, Wei, Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Varma, Achintya, Chen, X. Steven, Martin, Eden R., Wang, Lily
Publicado 2022

Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC BeadChip microarrays

por Zhang, Wei, Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Lukacsovich, David, Varma, Achintya, Chen, X. Steven, Kunkle, Brian, Martin, Eden R., Wang, Lily
Publicado 2023

Phenotypic Consequences of Copy Number Variation: Insights from Smith-Magenis and Potocki-Lupski Syndrome Mouse Models

por Ricard, Guénola, Molina, Jessica, Chrast, Jacqueline, Gu, Wenli, Gheldof, Nele, Pradervand, Sylvain, Schütz, Frédéric, Young, Juan I., Lupski, James R., Reymond, Alexandre, Walz, Katherina
Publicado 2010

coMethDMR: accurate identification of co-methylated and differentially methylated regions in epigenome-wide association studies with continuous phenotypes

por Gomez, Lissette, Odom, Gabriel J, Young, Juan I, Martin, Eden R, Liu, Lizhong, Chen, Xi, Griswold, Anthony J, Gao, Zhen, Zhang, Lanyu, Wang, Lily
Publicado 2019

Characterization of a Trpc6 Transgenic Mouse Associated with Early Onset FSGS

por Canales, Cesar P., Krall, Paola, Kairath, Pamela, Perez, Irene C., Fragoso, Miryam A., Carmona-Mora, Paulina, Ruiz, Phillip, Reiser, Jochen, Young, Juan I., Walz, Katherina
Publicado 2014

Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease

por Zhang, Lanyu, Silva, Tiago C., Young, Juan I., Gomez, Lissette, Schmidt, Michael A., Hamilton-Nelson, Kara L., Kunkle, Brian W., Chen, Xi, Martin, Eden R., Wang, Lily
Publicado 2020