Epigenetic Mechanisms in Immune Disease: The Significance of Toll-Like Receptor-Binding Extracellular Vesicle-Encapsulated microRNA

por Bosch, Steffi, Young, Nicholas A., Mignot, Grégoire, Bach, Jean-Marie
Publicado 2020

Aberrant Muscle Antigen Exposure in Mice Is Sufficient to Cause Myositis in a Treg Cell–Deficient Milieu

por Young, Nicholas A, Sharma, Rahul, Friedman, Alexandra K, Kaffenberger, Benjamin H, Bolon, Brad, Jarjour, Wael N
Publicado 2013

A chimeric human–mouse model of Sjögren's syndrome

por Young, Nicholas A., Wu, Lai-Chu, Bruss, Michael, Kaffenberger, Benjamin H., Hampton, Jeffrey, Bolon, Brad, Jarjour, Wael N.
Publicado 2014

Aromatase-Inhibitor-Induced Musculoskeletal Inflammation Is Observed Independent of Oophorectomy in a Novel Mouse Model

por Young, Nicholas A., Hampton, Jeffrey, Sharma, Juhi, Jablonski, Kyle, DeVries, Courtney, Bratasz, Anna, Wu, Lai-Chu, Lustberg, Maryam, Reinbolt, Raquel, Jarjour, Wael N.
Publicado 2022

Antigen-driven T cell-macrophage interactions mediate the interface between innate and adaptive immunity in histidyl-tRNA synthetase-induced myositis

por Reay, Daniel P., Tabib, Tracy, Wang, Ying, Oriss, Timothy B., Young, Nicholas A., Lafyatis, Robert A., Jarjour, Wael N., Clemens, Paula R., Ascherman, Dana P.
Publicado 2023

Oral Administration of Nano-Emulsion Curcumin in Mice Suppresses Inflammatory-Induced NFκB Signaling and Macrophage Migration

por Young, Nicholas A., Bruss, Michael S., Gardner, Mark, Willis, William L., Mo, Xiaokui, Valiente, Giancarlo R., Cao, Yu, Liu, Zhongfa, Jarjour, Wael N., Wu, Lai-Chu
Publicado 2014

Therapeutic Development of Mesenchymal Stem Cells or Their Extracellular Vesicles to Inhibit Autoimmune-Mediated Inflammatory Processes in Systemic Lupus Erythematosus

por Sharma, Juhi, Hampton, Jeffrey M., Valiente, Giancarlo R., Wada, Takuma, Steigelman, Holly, Young, Matthew C., Spurbeck, Rachel R., Blazek, Alisa D., Bösh, Steffi, Jarjour, Wael N., Young, Nicholas A.
Publicado 2017

CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions

por Amici, Stephanie A., Young, Nicholas A., Narvaez-Miranda, Janiret, Jablonski, Kyle A., Arcos, Jesus, Rosas, Lucia, Papenfuss, Tracey L., Torrelles, Jordi B., Jarjour, Wael N., Guerau-de-Arellano, Mireia
Publicado 2018

Physical activity prevents acute inflammation in a gout model by downregulation of TLR2 on circulating neutrophils as well as inhibition of serum CXCL1 and is associated with decre...

por Jablonski, Kyle, Young, Nicholas A., Henry, Caitlin, Caution, Kyle, Kalyanasundaram, Anuradha, Okafor, Ifeoma, Harb, Peter, Schwarz, Emmy, Consiglio, Paul, Cirimotich, Chris M., Bratasz, Anna, Sarkar, Anasuya, Amer, Amal O., Jarjour, Wael N., Schlesinger, Naomi
Publicado 2020

Daily Moderate Exercise Is Beneficial and Social Stress Is Detrimental to Disease Pathology in Murine Lupus Nephritis

por Aqel, Saba I., Hampton, Jeffrey M., Bruss, Michael, Jones, Kendra T., Valiente, Giancarlo R., Wu, Lai-Chu, Young, Matthew C., Willis, William L., Ardoin, Stacy, Agarwal, Sudha, Bolon, Brad, Powell, Nicole, Sheridan, John, Schlesinger, Naomi, Jarjour, Wael N., Young, Nicholas A.
Publicado 2017

Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation

por Carey, Heather A., Hildreth, Blake E., Geisler, Jennifer A., Nickel, Mara C., Cabrera, Jennifer, Ghosh, Sankha, Jiang, Yue, Yan, Jing, Lee, James, Makam, Sandeep, Young, Nicholas A., Valiente, Giancarlo R., Jarjour, Wael N., Huang, Kun, Rosol, Thomas J., Toribio, Ramiro E., Charles, Julia F., Ostrowski, Michael C., Sharma, Sudarshana M.
Publicado 2018