CstF-64 supports pluripotency and regulates cell cycle progression in embryonic stem cells through histone 3′ end processing

por Youngblood, Bradford A., Grozdanov, Petar N., MacDonald, Clinton C.
Publicado 2014

Human leukemia inhibitory factor produced by the ExpressTec method from rice (Oryza sativa L.) is active in human neural stem cells and mouse induced pluripotent stem cells

por Alfano, Randall, Youngblood, Bradford A, Zhang, Deshui, Huang, Ning, MacDonald, Clinton C
Publicado 2014

Mast cell activation is associated with post‐acute COVID‐19 syndrome

por Wechsler, Joshua B., Butuci, Melina, Wong, Alan, Kamboj, Amol P., Youngblood, Bradford A.
Publicado 2021

The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation

por Korver, Wouter, Wong, Alan, Gebremeskel, Simon, Negri, Gian Luca, Schanin, Julia, Chang, Katherine, Leung, John, Benet, Zachary, Luu, Thuy, Brock, Emily C., Luehrsen, Kenneth, Xu, Alan, Youngblood, Bradford A.
Publicado 2022

Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells

por Schanin, Julia, Korver, Wouter, Brock, Emily C., Leung, John, Benet, Zachary, Luu, Thuy, Chang, Katherine, Xu, Alan, De Freitas, Naomi, Luehrsen, Kenneth, Brehm, Michael A., Wong, Alan, Youngblood, Bradford A.
Publicado 2022

Discovery, Function, and Therapeutic Targeting of Siglec-8

por Youngblood, Bradford A., Leung, John, Falahati, Rustom, Williams, Jason, Schanin, Julia, Brock, Emily C., Singh, Bhupinder, Chang, Alan T., O’Sullivan, Jeremy A., Schleimer, Robert P., Tomasevic, Nenad, Bebbington, Christopher R., Bochner, Bruce S.
Publicado 2020

Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody

por Gebremeskel, Simon, Schanin, Julia, Coyle, Krysta M., Butuci, Melina, Luu, Thuy, Brock, Emily C., Xu, Alan, Wong, Alan, Leung, John, Korver, Wouter, Morin, Ryan D., Schleimer, Robert P., Bochner, Bruce S., Youngblood, Bradford A.
Publicado 2021

The Number of MRGPRX2-Expressing Cells Is Increased in Skin Lesions of Patients With Indolent Systemic Mastocytosis, But Is Not Linked to Symptom Severity

por Pyatilova, Polina, Ashry, Tameem, Luo, Yanyan, He, Jiajun, Bonnekoh, Hanna, Jiao, Qingqing, Moñino-Romero, Sherezade, Hu, Man, Scheffel, Jörg, Frischbutter, Stefan, Hermans, Maud A. W., Youngblood, Bradford A., Maurer, Marcus, Siebenhaar, Frank, Kolkhir, Pavel
Publicado 2022

A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation

por Schanin, Julia, Gebremeskel, Simon, Korver, Wouter, Falahati, Rustom, Butuci, Melina, Haw, Tatt Jhong, Nair, Prema M., Liu, Gang, Hansbro, Nicole G., Hansbro, Philip M., Evensen, Erik, Brock, Emily C., Xu, Alan, Wong, Alan, Leung, John, Bebbington, Christopher, Tomasevic, Nenad, Youngblood, Bradford A.
Publicado 2020

Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells

por Robida, Piper A., Rische, Clayton H., Morgenstern, Netali Ben-Baruch, Janarthanam, Rethavathi, Cao, Yun, Krier-Burris, Rebecca A., Korver, Wouter, Xu, Alan, Luu, Thuy, Schanin, Julia, Leung, John, Rothenberg, Marc E., Wechsler, Joshua B., Youngblood, Bradford A., Bochner, Bruce S., O’Sullivan, Jeremy A.
Publicado 2022