Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain

por Catalano, Karyn J., Maddux, Betty A., Szary, Jaroslaw, Youngren, Jack F., Goldfine, Ira D., Schaufele, Fred
Publicado 2014

Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity

por Masharani, Umesh, Gjerde, Christine, McCoy, Shelley, Maddux, Betty A, Hessler, Danielle, Goldfine, Ira D, Youngren, Jack F
Publicado 2012

Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle

por Masharani, Umesh B., Maddux, Betty A., Li, Xiaojuan, Sakkas, Giorgos K., Mulligan, Kathleen, Schambelan, Morris, Goldfine, Ira D., Youngren, Jack F.
Publicado 2011

Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer

por Podolak, Jennifer, Eilers, Kristi, Newby, Timothy, Slottke, Rachel, Tucker, Erin, Olson, Susan B., Lue, Hui-Wen, Youngren, Jack, Aggarwal, Rahul, Small, Eric J., Graff, Julie N., Alumkal, Joshi J., Beer, Tomasz M., Thomas, George V.
Publicado 2017

Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance

por Alumkal, Joshi J., Sun, Duanchen, Lu, Eric, Beer, Tomasz M., Thomas, George V., Latour, Emile, Aggarwal, Rahul, Cetnar, Jeremy, Ryan, Charles J., Tabatabaei, Shaadi, Bailey, Shawna, Turina, Claire B., Quigley, David A., Guan, Xiangnan, Foye, Adam, Youngren, Jack F., Urrutia, Joshua, Huang, Jiaoti, Weinstein, Alana S., Friedl, Verena, Rettig, Matthew, Reiter, Robert E., Spratt, Daniel E., Gleave, Martin, Evans, Christopher P., Stuart, Joshua M., Chen, Yiyi, Feng, Felix Y., Small, Eric J., Witte, Owen N., Xia, Zheng
Publicado 2020

Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity

por Westbrook, Thomas C., Guan, Xiangnan, Rodansky, Eva, Flores, Diana, Liu, Chia Jen, Udager, Aaron M., Patel, Radhika A., Haffner, Michael C., Hu, Ya-Mei, Sun, Duanchen, Beer, Tomasz M., Foye, Adam, Aggarwal, Rahul, Quigley, David A., Youngren, Jack F., Ryan, Charles J., Gleave, Martin, Wang, Yuzhuo, Huang, Jiaoti, Coleman, Ilsa, Morrissey, Colm, Nelson, Peter S., Evans, Christopher P., Lara, Primo, Reiter, Robert E., Witte, Owen, Rettig, Matthew, Wong, Christopher K., Weinstein, Alana S., Uzunangelov, Vlado, Stuart, Josh M., Thomas, George V., Feng, Felix Y., Small, Eric J., Yates, Joel A., Xia, Zheng, Alumkal, Joshi J.
Publicado 2022