Cryo-EM as a tool to study bacterial efflux systems and the membrane proteome

por Klenotic, Philip A, Morgan, Christopher E, Yu, Edward W
Publicado 2021

Simultaneous solving high-resolution structures of various enzymes from human kidney microsomes

por Lyu, Meinan, Su, Chih-Chia, Miyagi, Masaru, Yu, Edward W
Publicado 2022

Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity

por Zhang, Zhemin, Morgan, Christopher E., Cui, Meng, Yu, Edward W.
Publicado 2023

Cryo-EM Structures of the Klebsiella pneumoniae AcrB Multidrug Efflux Pump

por Zhang, Zhemin, Morgan, Christopher E., Bonomo, Robert A., Yu, Edward W.
Publicado 2023

Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii

por Zhang, Zhemin, Morgan, Christopher E., Bonomo, Robert A., Yu, Edward W.
Publicado 2021

An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii

por Morgan, Christopher E., Zhang, Zhemin, Bonomo, Robert A., Yu, Edward W.
Publicado 2022

Toward structural-omics of the bovine retinal pigment epithelium

por Morgan, Christopher E., Zhang, Zhemin, Miyagi, Masaru, Golczak, Marcin, Yu, Edward W.
Publicado 2022

The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening

por Zheng, Fudan, Robertson, Alan P., Abongwa, Melanie, Yu, Edward W., Martin, Richard J.
Publicado 2016

Response to Comment on “Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling”

por Moseng, Mitchell A., Su, Chih-Chia, Klenotic, Philip A., Delpire, Eric, Yu, Edward W.
Publicado 2023

A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes

por Tringides, Marios L, Zhang, Zhemin, Morgan, Christopher E, Su, Chih-Chia, Yu, Edward W
Publicado 2022

Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance

por Zhang, Zhemin, Lizer, Nicholas, Wu, Zuowei, Morgan, Christopher E., Yan, Yuqi, Zhang, Qijing, Yu, Edward W.
Publicado 2023

Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport

por Su, Chih-Chia, Klenotic, Philip A., Cui, Meng, Lyu, Meinan, Morgan, Christopher E., Yu, Edward W.
Publicado 2021

Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump

por Lyu, Meinan, Ayala, Julio C., Chirakos, Isabella, Su, Chih-Chia, Shafer, William M., Yu, Edward W.
Publicado 2022

High-resolution structural-omics of human liver enzymes

por Su, Chih-Chia, Lyu, Meinan, Zhang, Zhemin, Miyagi, Masaru, Huang, Wei, Taylor, Derek J., Yu, Edward W.
Publicado 2023

A “Build and Retrieve” methodology to simultaneously solve cryo-EM structures of membrane proteins

por Su, Chih-Chia, Lyu, Meinan, Morgan, Christopher E., Bolla, Jani Reddy, Robinson, Carol V., Yu, Edward W.
Publicado 2021

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport

por Long, Feng, Su, Chih-Chia, Zimmermann, Michael T., Boyken, Scott E., Rajashankar, Kanagalaghatta R., Jernigan, Robert L., Yu, Edward W.
Publicado 2010

(S)-5-ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor

por Zheng, Fudan, Du, Xiangwei, Chou, Tsung-Han, Robertson, Alan P., Yu, Edward W., VanVeller, Brett, Martin, Richard J.
Publicado 2016

Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development

por Morgan, Christopher E., Huang, Wei, Rudin, Susan D., Taylor, Derek J., Kirby, James E., Bonomo, Robert A., Yu, Edward W.
Publicado 2020

Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export

por Moseng, Mitchell A., Lyu, Meinan, Pipatpolkai, Tanadet, Glaza, Przemyslaw, Emerson, Corey C., Stewart, Phoebe L., Stansfeld, Phillip J., Yu, Edward W.
Publicado 2021

Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates

por Morgan, Christopher E., Glaza, Przemyslaw, Leus, Inga V., Trinh, Anhthu, Su, Chih-Chia, Cui, Meng, Zgurskaya, Helen I., Yu, Edward W.
Publicado 2021