The Lupus‐Associated Fcγ Receptor IIb–I232T Polymorphism Results in Impairment in the Negative Selection of Low‐Affinity Germinal Center B Cells Via c‐Abl in Mice

por Jhou, Jyun‐Pei, Yu, I‐Shing, Hwai, Haw, Chen, Chih‐Shan, Chen, Pei‐Lung, Tzeng, Shiang‐Jong
Publicado 2018

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy

por Pai, Chen-Hsueh, Yen, Ching-Tzu, Chen, Chie-Pein, Yu, I-Shing, Lin, Shu-Wha, Lin, Shu-Rung
Publicado 2016

Current animal models of hemophilia: the state of the art

por Yen, Ching-Tzu, Fan, Meng-Ni, Yang, Yung-Li, Chou, Sheng-Chieh, Yu, I-Shing, Lin, Shu-Wha
Publicado 2016

Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells

por Chen, Chun-Yu, Yu, I-Shing, Pai, Chen-Hsueh, Lin, Chien-Yu, Lin, Shu-Rung, Chen, You-Tzung, Lin, Shu-Wha
Publicado 2019

Mice Lacking Connective Tissue Growth Factor in the Forebrain Exhibit Delayed Seizure Response, Reduced C-Fos Expression and Different Microglial Phenotype Following Acute PTZ Inje...

por Siow, Pei-Fen, Tsao, Chih-Yu, Chang, Ho-Ching, Chen, Chwen-Yu, Yu, I-Shing, Lee, Kuang-Yung, Lee, Li-Jen
Publicado 2020

Sun1 deficiency leads to cerebellar ataxia in mice

por Wang, Jing-Ya, Yu, I.-Shing, Huang, Chien-Chi, Chen, Chia-Yen, Wang, Wan-Ping, Lin, Shu-Wha, Jeang, Kuan-Teh, Chi, Ya-Hui
Publicado 2015

Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4

por Jao, Tzu-Ming, Li, Ya-Lin, Lin, Shu-Wha, Tzeng, Sheng-Tai, Yu, I-Shing, Yen, Sou-Jhy, Tsai, Ming-Hong, Yang, Ya-Chien
Publicado 2016

Genetic Elimination of Connective Tissue Growth Factor in the Forebrain Affects Subplate Neurons in the Cortex and Oligodendrocytes in the Underlying White Matter

por Yu, I-Shing, Chang, Ho-Ching, Chen, Ko-Chien, Lu, Yi-Ling, Shy, Horng-Tzer, Chen, Chwen-Yu, Lee, Kuang-Yung, Lee, Li-Jen
Publicado 2019

Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice

por Wang, Ya-Yun, Ke, Chih-Chun, Chen, Yen-Lin, Lin, Yu-Hua, Yu, I-Shing, Ku, Wei-Chi, O’Bryan, Moira K., Lin, Ying-Hung
Publicado 2020

SEPT12-Microtubule Complexes Are Required for Sperm Head and Tail Formation

por Kuo, Pao-Lin, Chiang, Han-Sun, Wang, Ya-Yun, Kuo, Yung-Che, Chen, Mei-Feng, Yu, I-Shing, Teng, Yen-Ni, Lin, Shu-Wha, Lin, Ying-Hung
Publicado 2013

Differences in the Pathogenicity of the p.H723R Mutation of the Common Deafness-Associated SLC26A4 Gene in Humans and Mice

por Lu, Ying-Chang, Wu, Chen-Chi, Yang, Ting-Hua, Lin, Yin-Hung, Yu, I-Shing, Lin, Shu-Wha, Chang, Qing, Lin, Xi, Wong, Jau-Min, Hsu, Chuan-Jen
Publicado 2013

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

por Adair, Brian D., Alonso, José L., van Agthoven, Johannes, Hayes, Vincent, Ahn, Hyun Sook, Yu, I-Shing, Lin, Shu-Wha, Xiong, Jian-Ping, Poncz, Mortimer, Arnaout, M. Amin
Publicado 2020

Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency

por Lin, Meng-Hsuan, Chen, Jen-Chi, Tian, Xuejiao, Lee, Chia-Ming, Yu, I-Shing, Lo, Yi-Fen, Uchida, Shinichi, Huang, Chou-Long, Chen, Bi-Chang, Cheng, Chih-Jen
Publicado 2021

Human X-linked Intellectual Disability Factor CUL4B Is Required for Post-meiotic Sperm Development and Male Fertility

por Lin, Chien-Yu, Chen, Chun-Yu, Yu, Chih-Hsiang, Yu, I-Shing, Lin, Shu-Rung, Wu, June-Tai, Lin, Ying-Hung, Kuo, Pao-Lin, Wu, Jui-Ching, Lin, Shu-Wha
Publicado 2016

Aryl Hydrocarbon Receptor Downregulates MYCN Expression and Promotes Cell Differentiation of Neuroblastoma

por Wu, Pei-Yi, Liao, Yung-Feng, Juan, Hsueh-Fen, Huang, Hsuan-Cheng, Wang, Bo-Jeng, Lu, Yen-Lin, Yu, I-Shing, Shih, Yu-Yin, Jeng, Yung-Ming, Hsu, Wen-Ming, Lee, Hsinyu
Publicado 2014

The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation

por Lee, Chih-Yuan, Lai, Ting-Yu, Tsai, Meng-Kun, Chang, Yung-Chi, Ho, Yu-Hsin, Yu, I-Shing, Yeh, Tzu-Wen, Chou, Chih-Chang, Lin, You-Sheng, Lawrence, Toby, Hsu, Li-Chung
Publicado 2017

Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis

por Pai, Chen-Hsueh, Lin, Shu-Rung, Liu, Chia-Hao, Pan, Szu-Yu, Hsu, Hao, Chen, Yi-Ting, Yen, Ching-Tzu, Yu, I-Shing, Wu, Hua-Lin, Lin, Shuei-Liong, Lin, Shu-Wha
Publicado 2020

Toward the Pathogenicity of the SLC26A4 p.C565Y Variant Using a Genetically Driven Mouse Model

por Hu, Chin-Ju, Lu, Ying-Chang, Yang, Ting-Hua, Chan, Yen-Hui, Tsai, Cheng-Yu, Yu, I-Shing, Lin, Shu-Wha, Liu, Tien-Chen, Cheng, Yen-Fu, Wu, Chen-Chi, Hsu, Chuan-Jen
Publicado 2021

Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation

por Lin, Chia-Ching, Shen, Yi-Ru, Chang, Chi-Chih, Guo, Xiang-Yi, Young, Yun-Yun, Lai, Ting-Yu, Yu, I-Shing, Lee, Chih-Yuan, Chuang, Tsung-Hsien, Tsai, Hsin-Yue, Hsu, Li-Chung
Publicado 2021

Establishment of a Knock-In Mouse Model with the SLC26A4 c.919-2A>G Mutation and Characterization of Its Pathology

por Lu, Ying-Chang, Wu, Chen-Chi, Shen, Wen-Sheng, Yang, Ting-Hua, Yeh, Te-Huei, Chen, Pei-Jer, Yu, I-Shing, Lin, Shu-Wha, Wong, Jau-Min, Chang, Qing, Lin, Xi, Hsu, Chuan-Jen
Publicado 2011