Recovering Drug-Induced Apoptosis Subnetwork from Connectivity Map Data

por Yu, Jiyang, Putcha, Preeti, Silva, Jose M.
Publicado 2015

SJARACNe: a scalable software tool for gene network reverse engineering from big data

por Khatamian, Alireza, Paull, Evan O, Califano, Andrea, Yu, Jiyang
Publicado 2019

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcine...

por Tosello, Valeria, Saccomani, Valentina, Yu, Jiyang, Bordin, Fulvio, Amadori, Alberto, Piovan, Erich
Publicado 2016

Network Approaches for Dissecting the Immune System

por Hao Shi, Yan, Koon-Kiu, Ding, Liang, Qian, Chenxi, Chi, Hongbo, Yu, Jiyang
Publicado 2020

MYC is a critical target of FBXW7

por Sato, Mai, Rodriguez-Barrueco, Ruth, Yu, Jiyang, Do, Catherine, Silva, Jose M., Gautier, Jean
Publicado 2014

Silymarin’s Inhibition and Treatment Effects for Alzheimer’s Disease

por Guo, Hong, Cao, Hui, Cui, Xiaowei, Zheng, Wenxiu, Wang, Shanshan, Yu, Jiyang, Chen, Zhi
Publicado 2019

INSP-09. Using genetically engineered mouse models and patient-derived orthotopic xenografts to develop new therapies for pediatric brain tumors.

por Jonchere, Barbara, Pribnow, Allison, Morfouace, Marie, Shelat, Anang, Yu, Jiyang, Rankovic, Zoran, Gajjar, Amar, Northcott, Paul A, Robinson, Giles W, Roussel, Martine F
Publicado 2022

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

por Cheng, Haiying, Zhang, Zhenfeng, Rodriguez-Barrueco, Ruth, Borczuk, Alain, Liu, Huijie, Yu, Jiyang, Silva, Jose M., Cheng, Simon K., Perez-Soler, Roman, Halmos, Balazs
Publicado 2015

Smurf2 inhibition enhances chemotherapy and radiation sensitivity in non-small-cell lung cancer

por Chaudhary, Kunal R., Kinslow, Connor J., Cheng, Haiying, Silva, Jose M., Yu, Jiyang, Wang, Tony. J., Hei, Tom K., Halmos, Balazs, Cheng, Simon K.
Publicado 2022

Spatiotemporal regulation of cholangiocarcinoma growth and dissemination by peritumoral myofibroblasts in a Vcam1-dependent manner

por Tian, Cheng, Li, Liyuan, Pan, Qingfei, Xu, Beisi, Li, Yizhen, Fan, Li, Brown, Anthony, Morrison, Michelle, Dey, Kaushik, Yang, Jun J., Yu, Jiyang, Glazer, Evan S., Zhu, Liqin
Publicado 2023

Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma

por Boboila, Shuobo, Lopez, Gonzalo, Yu, Jiyang, Banerjee, Debarshi, Kadenhe-Chiweshe, Angela, Connolly, Eileen P., Kandel, Jessica J., Rajbhandari, Presha, Silva, Jose M., Califano, Andrea, Yamashiro, Darrell J.
Publicado 2018

Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas

por Luo, Zaili, Dong, Xinran, Yu, Jianzhong, Xia, Yong, Berry, Kalen P., Rao, Rohit, Xu, Lingli, Xue, Ping, Chen, Tong, Lin, Yifeng, Yu, Jiyang, Huang, Guoying, Li, Hao, Zhou, Wenhao, Lu, Q. Richard
Publicado 2021

PAX5 epigenetically orchestrates CD58 transcription and modulates blinatumomab response in acute lymphoblastic leukemia

por Li, Yizhen, Moriyama, Takaya, Yoshimura, Satoshi, Zhao, Xujie, Li, Zhenhua, Yang, Xu, Paietta, Elisabeth, Litzow, Mark R., Konopleva, Marina, Yu, Jiyang, Inaba, Hiroto, Ribeiro, Raul C., Pui, Ching-Hon, Yang, Jun J.
Publicado 2022

Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse

por Brown, Anthony, Pan, Qingfei, Fan, Li, Indersie, Emilie, Tian, Cheng, Timchenko, Nikolai, Li, Liyuan, Hansen, Baranda S., Tan, Haiyan, Lu, Meifen, Peng, Junmin, Pruett-Miller, Shondra M., Yu, Jiyang, Cairo, Stefano, Zhu, Liqin
Publicado 2023

miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy

por Rodriguez-Barrueco, Ruth, Nekritz, Erin A., Bertucci, François, Yu, Jiyang, Sanchez-Garcia, Felix, Zeleke, Tizita Z., Gorbatenko, Andrej, Birnbaum, Daniel, Ezhkova, Elena, Cordon-Cardo, Carlos, Finetti, Pascal, Llobet-Navas, David, Silva, Jose M.
Publicado 2017

Spontaneous lymphoblastoid cell lines from patients with Epstein-Barr virus infection show highly variable proliferation characteristics that correlate with the expression levels o...

por Delecluse, Susanne, Yu, Jiyang, Bernhardt, Katharina, Haar, Janina, Poirey, Remy, Tsai, Ming-Han, Kiblawi, Rama, Kopp-Schneider, Annette, Schnitzler, Paul, Zeier, Martin, Dreger, Peter, Wuchter, Patrick, Bulut, Olcay Cem, Behrends, Uta, Delecluse, Henri-Jacques
Publicado 2019

Combination of Ribociclib and Gemcitabine for the Treatment of Medulloblastoma

por Pribnow, Allison, Jonchere, Barbara, Liu, Jingjing, Smith, Kyle S., Campagne, Olivia, Xu, Ke, Robinson, Sarah, Patel, Yogesh, Onar-Thomas, Arzu, Wu, Gang, Stewart, Clinton F., Northcott, Paul A., Yu, Jiyang, Robinson, Giles W., Roussel, Martine F.
Publicado 2022

Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo

por Jonchere, Barbara, Williams, Justin, Zindy, Frederique, Liu, Jingjing, Robinson, Sarah, Farmer, Dana M., Min, Jaeki, Yang, Lei, Stripay, Jennifer L., Wang, Yingzhe, Freeman, Burgess B., Yu, Jiyang, Shelat, Anang A., Rankovic, Zoran, Roussel, Martine F.
Publicado 2023

MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus

por Canté-Barrett, Kirsten, Meijer, Mariska T., Cordo’, Valentina, Hagelaar, Rico, Yang, Wentao, Yu, Jiyang, Smits, Willem K., Nulle, Marloes E., Jansen, Joris P., Pieters, Rob, Yang, Jun J., Haigh, Jody J., Goossens, Steven, Meijerink, Jules P.P.
Publicado 2022

Targeting Regnase-1 programs long-lived effector T cells for cancer therapy

por Wei, Jun, Long, Lingyun, Zheng, Wenting, Dhungana, Yogesh, Lim, Seon Ah, Guy, Cliff, Wang, Yanyan, Wang, Yong-Dong, Qian, Chenxi, Xu, Beisi, Anil, KC, Saravia, Jordy, Huang, Hongling, Yu, Jiyang, Doench, John G., Geiger, Terrence L., Chi, Hongbo
Publicado 2019