Hit Generation in TB Drug Discovery: From Genome to Granuloma

por Yuan, Tianao, Sampson, Nicole S.
Publicado 2018

Correction to Hit Generation in TB Drug Discovery: From Genome to Granuloma

por Yuan, Tianao, Sampson, Nicole S.
Publicado 2019

The pursuit of mechanism of action: uncovering drug complexity in TB drug discovery

por Yuan, Tianao, Werman, Joshua M., Sampson, Nicole S.
Publicado 2021

A Chemoproteomic Approach to Elucidate the Mechanism of Action of 6-Azasteroids with Unique Activity in Mycobacteria

por Werman, Joshua M., Chen, Yu-Ching, Yuan, Tianao, Yang, Xinxin, Sampson, Nicole S.
Publicado 2023

Enzymatic β-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA

por Yuan, Tianao, Werman, Joshua M., Yin, Xingyu, Yang, Meng, Garcia-Diaz, Miguel, Sampson, Nicole S.
Publicado 2021

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities

por Yang, Xinxin, Yuan, Tianao, Ma, Rui, Chacko, Kieran I., Smith, Melissa, Deikus, Gintaras, Sebra, Robert, Kasarskis, Andrew, van Bakel, Harm, Franzblau, Scott G., Sampson, Nicole S.
Publicado 2019

IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria

por Gadbery, John E., Round, James W., Yuan, Tianao, Wipperman, Matthew F., Story, Keith T., Crowe, Adam M., Casabon, Israel, Liu, Jie, Yang, Xinxin, Eltis, Lindsay D., Sampson, Nicole S.
Publicado 2020

Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

por Rosa, Thabatta L. S. A., Marques, Maria Angela M., DeBoard, Zachary, Hutchins, Kelly, Silva, Carlos Adriano A., Montague, Christine R., Yuan, Tianao, Amaral, Julio J., Atella, Georgia C., Rosa, Patrícia S., Mattos, Katherine A., VanderVen, Brian C., Lahiri, Ramanuj, Sampson, Nicole S., Brennan, Patrick J., Belisle, John T., Pessolani, Maria Cristina V., Berrêdo-Pinho, Marcia
Publicado 2021

Corrigendum: Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

por Rosa, Thabatta L. S. A., Marques, Maria Angela M., DeBoard, Zachary, Hutchins, Kelly, Silva, Carlos Adriano A., Montague, Christine R., Yuan, Tianao, Amaral, Julio J., Atella, Georgia C., Rosa, Patrícia S., Mattos, Katherine A., VanderVen, Brian C., Lahiri, Ramanuj, Sampson, Nicole S., Brennan, Patrick J., Belisle, John T., Pessolani, Maria Cristina V., Berrêdo-Pinho, Marcia
Publicado 2021