Palladium-catalyzed chemoselective direct α-arylation of carbonyl compounds with chloroaryl triflates at the C–Cl site

por Chen, Zicong, Gu, Changxue, Yuen, On Ying, So, Chau Ming
Publicado 2022

Structural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysis

por Scipion, Clement P. M., Ghoshdastider, Umesh, Ferrer, Fernando J., Yuen, Tsz-Ying, Wongsantichon, Jantana, Robinson, Robert C.
Publicado 2018

Stapled β-Hairpin Antimicrobial Peptides with Improved Stability and Activity against Drug-Resistant Gram-Negative Bacteria

por Selvarajan, Vanitha, Tram, Nhan D. T., Xu, Jian, Ngen, Sarah T. Y., Koh, Jun-Jie, Teo, Jeanette W. P., Yuen, Tsz-Ying, Ee, Pui Lai Rachel
Publicado 2023

Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays

por Xiong Tan, Ban, Brown, Christopher J., Ferrer, Fernando J., Yuen, Tsz Ying, Quah, Soo Tng, Chan, Boon Hong, Jansson, Anna E., Teo, Hsiang Ling, Nordlund, Pär, Lane, David P.
Publicado 2015

Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles

por Yuen, Tsz Ying, Brown, Christopher J., Xue, Yuezhen, Tan, Yaw Sing, Ferrer Gago, Fernando J., Lee, Xue Er, Neo, Jin Yong, Thean, Dawn, Kaan, Hung Yi Kristal, Partridge, Anthony W., Verma, Chandra S., Lane, David P., Johannes, Charles W.
Publicado 2019

Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design

por Tan, Yaw Sing, Reeks, Judith, Brown, Christopher J., Thean, Dawn, Ferrer Gago, Fernando Jose, Yuen, Tsz Ying, Goh, Eunice Tze Leng, Lee, Xue Er Cheryl, Jennings, Claire E., Joseph, Thomas L., Lakshminarayanan, Rajamani, Lane, David P., Noble, Martin E. M., Verma, Chandra S.
Publicado 2016

Granzyme B PET Imaging of Combined Chemotherapy and Immune Checkpoint Inhibitor Therapy in Colon Cancer

por Goggi, Julian L, Hartimath, Siddesh V, Xuan, Tan Yun, Khanapur, Shivashankar, Jieu, Beverly, Chin, Hui Xian, Ramasamy, Boominathan, Cheng, Peter, Rong, Tang Jun, Fong, Yong Fui, Yuen, Tsz Ying, Msallam, Rasha, Chacko, Ann-Marie, Renia, Laurent, Johannes, Charles, Hwang, You Yi, Robins, Edward G
Publicado 2021

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties

por Watkins, Harriet A., Chakravarthy, Madhuri, Abhayawardana, Rekhati S., Gingell, Joseph J., Garelja, Michael, Pardamwar, Meenakshi, McElhinney, James M. W. R., Lathbridge, Alex, Constantine, Arran, Harris, Paul W. R., Yuen, Tsz-Ying, Brimble, Margaret A., Barwell, James, Poyner, David R., Woolley, Michael J., Conner, Alex C., Pioszak, Augen A., Reynolds, Christopher A., Hay, Debbie L.
Publicado 2016

Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties

por Partridge, Anthony W., Kaan, Hung Yi Kristal, Juang, Yu-Chi, Sadruddin, Ahmad, Lim, Shuhui, Brown, Christopher J., Ng, Simon, Thean, Dawn, Ferrer, Fernando, Johannes, Charles, Yuen, Tsz Ying, Kannan, Srinivasaraghavan, Aronica, Pietro, Tan, Yaw Sing, Pradhan, Mohan R., Verma, Chandra S., Hochman, Jerome, Chen, Shiying, Wan, Hui, Ha, Sookhee, Sherborne, Brad, Lane, David P., Sawyer, Tomi K.
Publicado 2019

Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability

por Kannan, Srinivasaraghavan, Aronica, Pietro G. A., Ng, Simon, Gek Lian, Dawn Thean, Frosi, Yuri, Chee, Sharon, Shimin, Jiang, Yuen, Tsz Ying, Sadruddin, Ahmad, Kaan, Hung Yi Kristal, Chandramohan, Arun, Wong, Jin Huei, Tan, Yaw Sing, Chang, Zi Wei, Ferrer-Gago, Fernando J., Arumugam, Prakash, Han, Yi, Chen, Shiying, Rénia, Laurent, Brown, Christopher J., Johannes, Charles W., Henry, Brian, Lane, David P., Sawyer, Tomi K., Verma, Chandra S., Partridge, Anthony W.
Publicado 2020

Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling

por Lim, Shuhui, Boyer, Nicolas, Boo, Nicole, Huang, Chunhui, Venkatachalam, Gireedhar, Angela Juang, Yu-Chi, Garrigou, Michael, Kaan, Hung Yi Kristal, Duggal, Ruchia, Peh, Khong Ming, Sadruddin, Ahmad, Gopal, Pooja, Yuen, Tsz Ying, Ng, Simon, Kannan, Srinivasaraghavan, Brown, Christopher J., Verma, Chandra S., Orth, Peter, Peier, Andrea, Ge, Lan, Yu, Xiang, Bhatt, Bhavana, Chen, Feifei, Wang, Erjia, Li, Nianyu Jason, Gonzales, Raymond J., Stoeck, Alexander, Henry, Brian, Sawyer, Tomi K., Lane, David P., Johannes, Charles W., Biswas, Kaustav, Partridge, Anthony W.
Publicado 2021