Novel RT-ddPCR Assays for determining the transcriptional profile of SARS-CoV-2

por Telwatte, Sushama, Kumar, Nitasha, Vallejo-Gracia, Albert, Kumar, G. Renuka, Lu, Chuanyi M., Ott, Melanie, Wong, Joseph K., Yukl, Steven A.
Publicado 2021

Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA

por Telwatte, Sushama, Kumar, Nitasha, Vallejo-Gracia, Albert, Kumar, G. Renuka, Lu, Chuanyi M., Ott, Melanie, Wong, Joseph K., Yukl, Steven A.
Publicado 2021

Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

por Telwatte, Sushama, Morón-López, Sara, Aran, Dvir, Kim, Peggy, Hsieh, Christine, Joshi, Sunil, Montano, Mauricio, Greene, Warner C., Butte, Atul J., Wong, Joseph K., Yukl, Steven A.
Publicado 2019

Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts

por Telwatte, Sushama, Martin, Holly Anne, Marczak, Ryan, Fozouni, Parinaz, Vallejo-Gracia, Albert, Kumar, G. Renuka, Murray, Victoria, Lee, Sulggi, Ott, Melanie, Wong, Joseph K., Yukl, Steven A.
Publicado 2022

Adaptation of Droplet Digital PCR-Based HIV Transcription Profiling to Digital PCR and Association of HIV Transcription and Total or Intact HIV DNA

por Tumpach, Carolin, Rhodes, Ajantha, Kim, Youry, Ong, Jesslyn, Liu, Haoming, Chibo, Doris, Druce, Julian, Williamson, Deborah, Hoh, Rebecca, Deeks, Steven G., Yukl, Steven A., Roche, Michael, Lewin, Sharon R., Telwatte, Sushama
Publicado 2023

Site-Specific Differences in T Cell Frequencies and Phenotypes in the Blood and Gut of HIV-Uninfected and ART-Treated HIV+ Adults

por Yukl, Steven A., Shergill, Amandeep K., Girling, Valerie, Li, Qingsheng, Killian, Maudi, Epling, Lorrie, Li, Peilin, Kaiser, Philipp, Haase, Ashley, Havlir, Diane V., McQuaid, Kenneth, Sinclair, Elizabeth, Wong, Joseph K.
Publicado 2015

Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency

por Telwatte, Sushama, Lee, Sulggi, Somsouk, Ma, Hatano, Hiroyu, Baker, Christopher, Kaiser, Philipp, Kim, Peggy, Chen, Tsui-Hua, Milush, Jeffrey, Hunt, Peter W., Deeks, Steven G., Wong, Joseph K., Yukl, Steven A.
Publicado 2018

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy

por Lee, Sulggi A., Bacchetti, Peter, Chomont, Nicolas, Fromentin, Remi, Lewin, Sharon R., O’Doherty, Una, Palmer, Sarah, Richman, Douglas D., Siliciano, Janet D., Yukl, Steven A., Deeks, Steven G., Burbelo, Peter D.
Publicado 2016

Tissue‐specific differences in HIV DNA levels and mechanisms that govern HIV transcription in blood, gut, genital tract and liver in ART‐treated women

por Moron‐Lopez, Sara, Xie, Guorui, Kim, Peggy, Siegel, David A, Lee, Sulggi, Wong, Joseph K, Price, Jennifer C, Elnachef, Najwa, Greenblatt, Ruth M, Tien, Phyllis C, Roan, Nadia R, Yukl, Steven A
Publicado 2021

CD4(+) and CD8(+) T Cell Activation Are Associated with HIV DNA in Resting CD4(+) T Cells

por Cockerham, Leslie R., Siliciano, Janet D., Sinclair, Elizabeth, O'Doherty, Una, Palmer, Sarah, Yukl, Steven A., Strain, Matt C., Chomont, Nicolas, Hecht, Frederick M., Siliciano, Robert F., Richman, Douglas D., Deeks, Steven G.
Publicado 2014

Human splice factors contribute to latent HIV infection in primary cell models and blood CD4(+) T cells from ART-treated individuals

por Moron-Lopez, Sara, Telwatte, Sushama, Sarabia, Indra, Battivelli, Emilie, Montano, Mauricio, Macedo, Amanda B., Aran, Dvir, Butte, Atul J., Jones, R. Brad, Bosque, Alberto, Verdin, Eric, Greene, Warner C., Wong, Joseph K., Yukl, Steven A.
Publicado 2020

Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses

por Einkauf, Kevin B., Osborn, Matthew R., Gao, Ce, Sun, Weiwei, Sun, Xiaoming, Lian, Xiaodong, Parsons, Elizabeth M., Gladkov, Gregory T., Seiger, Kyra W., Blackmer, Jane E., Jiang, Chenyang, Yukl, Steven A., Rosenberg, Eric S., Yu, Xu G., Lichterfeld, Mathias
Publicado 2022

Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection

por Hsiao, Feng, Frouard, Julie, Gramatica, Andrea, Xie, Guorui, Telwatte, Sushama, Lee, Guinevere Q., Roychoudhury, Pavitra, Schwarzer, Roland, Luo, Xiaoyu, Yukl, Steven A., Lee, Sulggi, Hoh, Rebecca, Deeks, Steven G., Jones, R. Brad, Cavrois, Marielle, Greene, Warner C., Roan, Nadia R.
Publicado 2020

Novel assays to investigate the mechanisms of latent infection with HIV-2

por Lu, Michael D., Telwatte, Sushama, Kumar, Nitasha, Ferreira, Fernanda, Martin, Holly Anne, Kadiyala, Gayatri Nikhila, Wedrychowski, Adam, Moron-Lopez, Sara, Chen, Tsui-Hua, Goecker, Erin A., Coombs, Robert W., Lu, Chuanyi M., Wong, Joseph K., Tsibris, Athe, Yukl, Steven A.
Publicado 2022

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals

por Cockerham, Leslie R., Yukl, Steven A., Harvill, Kara, Somsouk, Ma, Joshi, Sunil K., Sinclair, Elizabeth, Liegler, Teri, Hoh, Rebecca, Lyons, Sophie, Hunt, Peter W., Rupert, Adam, Sereti, Irini, Morcock, David R., Rhodes, Ajantha, Emson, Claire, Hellerstein, Marc K., Estes, Jacob D., Lewin, Sharon, Deeks, Steven G., Hatano, Hiroyu
Publicado 2017

Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

por Neidleman, Jason, Luo, Xiaoyu, Frouard, Julie, Xie, Guorui, Hsiao, Feng, Ma, Tongcui, Morcilla, Vincent, Lee, Ashley, Telwatte, Sushama, Thomas, Reuben, Tamaki, Whitney, Wheeler, Benjamin, Hoh, Rebecca, Somsouk, Ma, Vohra, Poonam, Milush, Jeffrey, James, Katherine Sholtis, Archin, Nancie M, Hunt, Peter W, Deeks, Steven G, Yukl, Steven A, Palmer, Sarah, Greene, Warner C, Roan, Nadia R
Publicado 2020

Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies

por Eriksson, Susanne, Graf, Erin H., Dahl, Viktor, Strain, Matthew C., Yukl, Steven A., Lysenko, Elena S., Bosch, Ronald J., Lai, Jun, Chioma, Stanley, Emad, Fatemeh, Abdel-Mohsen, Mohamed, Hoh, Rebecca, Hecht, Frederick, Hunt, Peter, Somsouk, Ma, Wong, Joseph, Johnston, Rowena, Siliciano, Robert F., Richman, Douglas D., O'Doherty, Una, Palmer, Sarah, Deeks, Steven G., Siliciano, Janet D.
Publicado 2013

Prospective Antiretroviral Treatment of Asymptomatic, HIV-1 Infected Controllers

por Hatano, Hiroyu, Yukl, Steven A., Ferre, April L., Graf, Erin H., Somsouk, Ma, Sinclair, Elizabeth, Abdel-Mohsen, Mohamed, Liegler, Teri, Harvill, Kara, Hoh, Rebecca, Palmer, Sarah, Bacchetti, Peter, Hunt, Peter W., Martin, Jeffrey N., McCune, Joseph M., Tracy, Russell P., Busch, Michael P., O'Doherty, Una, Shacklett, Barbara L., Wong, Joseph K., Deeks, Steven G.
Publicado 2013

Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

por Yukl, Steven A., Boritz, Eli, Busch, Michael, Bentsen, Christopher, Chun, Tae-Wook, Douek, Daniel, Eisele, Evelyn, Haase, Ashley, Ho, Ya-Chi, Hütter, Gero, Justement, J. Shawn, Keating, Sheila, Lee, Tzong-Hae, Li, Peilin, Murray, Danielle, Palmer, Sarah, Pilcher, Christopher, Pillai, Satish, Price, Richard W., Rothenberger, Meghan, Schacker, Timothy, Siliciano, Janet, Siliciano, Robert, Sinclair, Elizabeth, Strain, Matt, Wong, Joseph, Richman, Douglas, Deeks, Steven G.
Publicado 2013

Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART

por Bacchus-Souffan, Charline, Fitch, Mark, Symons, Jori, Abdel-Mohsen, Mohamed, Reeves, Daniel B., Hoh, Rebecca, Stone, Mars, Hiatt, Joseph, Kim, Peggy, Chopra, Abha, Ahn, Haelee, York, Vanessa A., Cameron, Daniel L., Hecht, Frederick M., Martin, Jeffrey N., Yukl, Steven A., Mallal, Simon, Cameron, Paul U., Deeks, Steven G., Schiffer, Joshua T., Lewin, Sharon R., Hellerstein, Marc K., McCune, Joseph M., Hunt, Peter W.
Publicado 2021